Jurnal Kesmas Prima Indonesia
Vol. 10 No. 2 (2026): July Edition

The Formulation, Characterization, and Antibacterial Activity of Solid Soap Containing Guava Leaf Extract (Psidium guajava L.) and Precipitated Calcium Carbonate

Sri Handayani (Institut Kesehatan Helvetia)
Hendri Faisal (Institut Kesehatan Helvetia)
Shaflina Izar (Institut Kesehatan Helvetia)
Togito Febrina Sitorus (Institut Kesehatan Helvetia)



Article Info

Publish Date
22 Jul 2026

Abstract

Bath soap is defined as a sodium compound with fatty acids used as a body cleanser, which generates foam and does not cause skin irritation. Beyond cleansing the skin from external dirt, soap can also function to eliminate bacterial skin infections. Prior investigations have verified that the saponins, tannins, and flavonoids concentrated in guava leaves exhibit robust antibacterial activity. The objective of this study was to determine the physicochemical properties of a solid soap formula containing the ethanol extract of guava leaf and precipitated calcium carbonate, including texture, color, pH, moisture content, hardness, and other relevant properties. This study employed a laboratory experimental research method. The procedure involved the preparation of guava leaf (Psidium guajava L.) simplicia, followed by extraction with a 70% ethanol solvent via maceration. Subsequently, the solid soap formulation was created using the guava leaf extract and precipitated calcium carbonate, followed by evaluation and antibacterial activity testing against Staphylococcus aureus bacteria. The pH evaluation test yielded an average value of 9.09 for the blank formula, while the average pH values for the active formulas were 9.13 for FI, 9.30 for FII, 9.23 for FIII, and 9.12 for the positive control (comparator). Based on the antibacterial testing results, the solid soap containing guava leaf ethanol extract demonstrated strong antibacterial activity against Staphylococcus aureus. The inhibition zone diameters were recorded as 0 mm for F0 (blank), 11.6 mm for FI (10% concentration), 10.9 mm for FII (15% concentration), 11 mm for FIII (20% concentration), and 11.3 mm for K+ (comparator). The research indicates that the ethanol extract of guava leaves combined with precipitated calcium carbonate (PCC) can be successfully formulated into a stable solid soap that meets the physical quality standard requirements according to the Indonesian National Standard (SNI).

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Journal Info

Abbrev

JKPI

Publisher

Subject

Health Professions Medicine & Pharmacology Nursing Public Health

Description

Jurnal Kesmas Prima Indonesia merupakan jurnal yang diterbitkan oleh Fakultas Kesehatan Masyarakat dengan frekuensi penerbitan dua kali setahun, yaitu pada bulan Januari dan Juli. Jurnal ini memuat naskah penelitian dan naskah studi literatur di bidang Ilmu Kesehatan Masyarakat yang meliputi ...