Indonesian Journal of Global Health Research
Vol. 8 No. 3 (2026): Indonesian Journal of Global Health Research

Analysis of Placental Profile in Pregnancy with Hypertension and Its Relationship with the Condition of the Newborn

Eftyaningrum Dwi Wahyu Astutik (Universitas Jayapura)
Endah Purwanti Handayani (Universitas Jayapura)
Harlinda Widia Putri (Universitas Jayapura)
Pranita Kartika Candra Nurhijraheni (Universitas Jayapura)



Article Info

Publish Date
18 Apr 2026

Abstract

Hypertension in pregnancy (HDK) is one of the main complications that contribute to maternal and infant morbidity and mortality. This study aims to analyze the placental profile in pregnancies with hypertension and its relationship with the condition of the newborn. This study used an observational analytical design with a case-control approach. The sample consisted of 60 respondents consisting of 30 mothers with HDK (case group) and 30 mothers without hypertension (control group), selected using consecutive sampling technique. Data analysis was performed using t-test, Chi-square, and logistic regression with a significance level of p < 0.05. There were significant differences in placental profiles between the case and control groups, where the HDK group had lower weight (420 ± 55 vs 510 ± 60 grams; p = 0.001), diameter (16.5 ± 1.8 vs 18.2 ± 1.5 cm; p = 0.002), and thickness (2.1 ± 0.4 vs 2.8 ± 0.5 cm; p = 0.001). The incidence of infarction (60.0 % vs 20.0%; p = 0.002) and calcification (66.7% vs 26.7%; p = 0.001) was higher in the HDK group. The condition of newborns in the HDK group showed a higher incidence of LBW ( 50.0 % vs. 20.0%; p = 0.015), APGAR <7 (40.0% vs. 16.7%; p = 0.032), and asphyxia (43.3% vs. 16.7%; p = 0.021). Analysis showed that low placental weight (OR=3.8 ; p = 0.008), infarction (OR=4.5; p = 0.004), and calcification (OR=3.9; p = 0.006) were significantly associated with the condition of newborns. Placental profiles in hypertensive pregnancies experienced significant changes and were closely associated with the condition of newborns.

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Journal Info

Abbrev

IJGHR

Publisher

Subject

Description

Indonesian Journal of Global Health Research is a open access, peer reviewed and refereed international journal. Indonesian Journal of Global Health Research aim to publish original research paper devoted to various area of all health sciences. Indonesian Journal of Global Health Research provides a ...