Jurnal Komunitas Farmasi Nasional
Vol. 6 No. 01 (2026): Jurnal Komunitas Farmasi Nasional

The FORMULASI LOTION FRAKSI ETANOL DAUN KETAPANG (Terminalia catappa L.) DENGAN VARIASI SETIL ALKOHOL SEBAGAI STIFFENING AGENT

Husnani Husnani (Unknown)
Sumarni Melly (akademi farmasi YARSI Pontianak)



Article Info

Publish Date
14 Aug 2026

Abstract

Excessive exposure to ultraviolet (UV) radiation can cause various skin disorders such as erythema, premature aging, hyperpigmentation, and skin cancer. The use of sunscreen is one of the preventive measures against skin damage caused by UV radiation. Indian almond leaves (Terminalia catappa Linn.) contain flavonoids, tannins, and phenolic compounds with antioxidant and photoprotective potential. This study aimed to formulate lotion from ethanol fraction of Indian almond leaves with varying concentrations of cetyl alcohol as a stiffening agent and evaluate its physical characteristics. The research method used an experimental design with three different formulas: Formula I (3% cetyl alcohol), Formula II (4%), and Formula III (5%). Evaluation included organoleptic, homogeneity, pH, viscosity, and spreadability tests. The results showed all three formulas were homogeneous with cream color, lemon aroma, semi-solid texture, and pH 7. Kruskal-Wallis test showed significant viscosity differences (p=0.026) with values of FI (3,833 cPs), FII (22,083 cPs), and FIII (39,750 cPs). ANOVA test showed significant spreadability differences (p=0.000) with values of FI (6.67 cm), FII (5.95 cm), and FIII (5.36 cm). All three formulas met the topical preparation spreadability requirements (5-7 cm). It can be concluded that variations in cetyl alcohol concentration significantly affect the viscosity and spreadability of ethanol fraction lotion from Indian almond leaves.

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Journal Info

Abbrev

jkfn

Publisher

Subject

Medicine & Pharmacology Public Health

Description

Jurnal Komunitas Farmasi Nasional adalah jurnal akses terbuka dan peer-review yang diterbitkan oleh Akademi Farmasi Yarsi Pontianak. Jurnal ini diterbitkan dua kali per tahun pada bulan Juni dan Desember. Jurnal Komunitas Farmasi Nasional menerbitkan artikel penelitian di bidang farmasi dan ilmu ...