Background: Primary healthcare anemia screening relies solely on hemoglobin, failing to comprehensively describe hematological characteristics compared to its combination with erythrocyte indices.Objective: This study analyzes determinant factors associated with anemia incidence based on haemoglobin (Hb) levels, erythrocyte indices, and maternal characteristics at the Prambanan Primary Health Care Center.Methods: This cross-sectional study included 96 pregnant women. Evaluated characteristics included maternal age, gestational age, parity, and iron (Fe) supplementation compliance. Haemoglobin levels and erythrocyte indices were measured. Data were analyzed using Fisher's exact and logistic regression tests. Results: Descriptively, 33.3% of pregnant women had anemia based on Hb, predominantly aged 20-35 years (27.1%), in the second trimester (15.6%), nulliparous (15.6%), and Fe-compliant (19.8%). Normocytic normochromic was the most common type (58.3%), followed by microcytic normochromic (20.8%) and microcytic hypochromic (20.8%). Statistical tests showed a significant association between anemia and gestational age (p<0.05; OR=2.14; 95% CI: 1.24-3.68). Gestational age was also strongly associated with normocytic normochromic (p<0.05; OR=3.21; 95% CI: 1.33–7.74) and microcytic hypochromic anemia (p<0.05; OR=3.71; 95% CI: 1.04–13.19).Conclusions: A significant association exists between anemia incidence and gestational age (OR=2.14). Gestational age is strongly associated with normocytic normochromic and microcytic hypochromic anemia types, with risk values of 3.21 and 3.71, respectively.
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