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INDONESIA
Jurnal Gizi Klinik Indonesia
Published by Universitas Gadjah Mada
ISSN : 1693900     EISSN : 25024140     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Nursing Public Health
Jurnal Gizi Klinik Indonesia merupakan jurnal ilmiah nasional terakreditasi yang memuat artikel penelitian (research article) di bidang gizi dan kesehatan, yang terkait aspek gizi klinis, gizi masyarakat, gizi olahraga, gizi molekular, biokimia gizi, pangan fungsional, serta pelayanan dan manajemen gizi. Jurnal Gizi Klinik Indonesia (JGKI) diterbitkan empat bulan sekali sejak terbit Juli 2004 hingga Maret 2011 (Volume 1-7), kemudian sejak Juli 2011 (Volume 8) JGKI diterbitkan setiap tiga bulan. Jurnal Gizi Klinik Indonesia diterbitkan oleh Minat S2 Gizi dan Kesehatan, Prodi S2 Ilmu Kesehatan Masyarakat, Fakultas Kedokteran Universitas Gadjah Mada bekerjasama dengan Persatuan Ahli Gizi Indonesia (PERSAGI) dan Asosiasi Dietisien Indonesia (AsDI).
Arjuna Subject : -
Articles 433 Documents
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Peningkatan aktivitas fagositosis dan produksi nitrit oksida pada makrofag peritoneum tikus Sprague Dawley yang diberi Lactobacillus plantarum Mut7 dan ekstrak serat ubi jalar Lily Arsanti Lestari; Marsetyawan Heparis Nur Ekandaru Soesatyo; Susi Iravati; Eni Harmayani
Jurnal Gizi Klinik Indonesia Vol 9, No 2 (2012): Oktober
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.15381

Abstract

Background: Macrophages play an important role as part of the innate immune response in the gut and they represent one of the first lines of nonspecific defense against bacterial invasion. Previous studies indicated that probiotics and prebiotics may act as an immunomodulator agents. Nevertheless, research on the immunomodulatory effect of local materials has never been performed.Objective: To study the effects of Lactobacillus plantarum Mut7 and sweet potato fiber on the activity and Nitric Oxide (NO) production of peritoneal macrophages of Sprague Dawley rats.Method: Ninety six Sprague Dawley rats aged 8 weeks were divided into two groups; A (not infected with Salmonella typhimurium) and B (infected with S. typhimurium). Each group was divided into 4 subgroups and assigned to standard AIN-93M diet (KON), 109 CFU/ml of L. plantarum Mut7 (PRO), modified AIN-93M diet with sweet potato fiber (PRE), and both component (SIN). After 3 weeks of treatment, 6 rats of each subgroup were sacrificed and the peritoneal macrophages were isolated and analysed for its activity and NO production. The rest of the rats continued the treatments for another 2 weeks. At the end of the experiment, they were sacrificed and the peritoneal macrophage were isolated and analysed for its activity and NO production.Results: Oral administration of  L. plantarum Mut7, sweet potato fiber, or both improve phagocytic activity of peritoneal macrophage which was indicated by an increase in the percentage of macrophages that phagocyte latex particles (p<0.05) and an increase in the number of latex particles engulfed by macrophages either after 3 or 5 weeks of treatment (p<0.05). Oral administration of L. plantarum Mut7, sweet potato fiber, or both were unable to increase the nitric oxide production after 3 weeks of treatment (p>0.05), but after 5 weeks of treatment the production of NO was significantly increased (p<0.05).Conclusion: L. plantarum Mut7, sweet potato fiber, or both increase the non specific immune response as they could improve the activity and NO production of peritoneal macrophages.
Senam aerobik dan konsumsi zat gizi serta pengaruhnya terhadap kadar kolesterol total darah wanita Siti Fatimah; Apoina Kartini
Jurnal Gizi Klinik Indonesia Vol 8, No 1 (2011): Juli
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.17727

Abstract

Background: Hypercholesterolemia is a condition in which levels of cholesterol in the blood above normal levels (≥ 240 mg/dl). Physical exercises done regularly useful in the regulation of cholesterol, is total cholesterol, LDL cholesterol and triglycerides in the blood decreased, while HDL cholesterol increased. Food has an important role in association with the incident hypercholesterolemia.Objective: The purpose of this study was to determine the effect of aerobic exercise on blood total cholesterol level of adult women in the city of Semarang.Method: This research was explanatory research with cross sectional study. Subject was women aged 20-49 years gymnastic participants, as a comparison group was a housewife who was not doing gymnastics. Twenty three samples for group2 by matching on nutritional status and age and with the sampling purposive sampling. Adequacy levels of carbohydrates, proteins, fats, and also vitamins A and C were obtained through 2x24-hour recall was not a sequence, and processed using NutriSurvey. Results of independent t-test used to determine the effect of cholesterol levels between groups, and chi square test was used to determine association with nutrient adequacy levels of total cholesterol.Results: The results showed no significant difference in mean total cholesterol level between groups of gymnastic participants (201.2 g/dl) with housewife group (208.3 g/dl). Housewife group was belonging to hypercholesterolemia by 52.2%, while in group of exercise participants at 43.5%. Sufficiency level of protein showed a role in the total cholesterol level of adult women.Conclusion: The aerobic gymnastics did not affect total cholesterol. Moderate level of protein adequacy contributes to the total cholesterol level of adult women.
Pemberian ekstra jus putih telur terhadap kadar albumin dan Hb pada penderita hipoalbuminemia Nurul Huda Syamsiatun; Tri Siswati
Jurnal Gizi Klinik Indonesia Vol 12, No 2 (2015): Oktober
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.22919

Abstract

Background: Hospitals malnutrition has been reported to occur in almost 40% of patients hospitalized. Hypoalbuminemia is one of sign of malnutrition. Hypoalbuminemia can be resolved with intravenous albumin and a high albumin diet can be done by administering an extra egg white (albumin) on diet. By feeding in the form of a refreshing juice will hopefully can increase the food intake, which is expected to help improve albumin and hemoglobin (Hb) in blood level.Objective: The aim of this research is knowing the effect of egg white juice of the albumin and Hb levels in patients hipoalbumin.Method: This type of research is experimental approach with pretest-posttest control group design. While the treatment effect assessed from differences in measurement results (albumin and Hb level) between the 2 groups. The study was conducted in Sardjito and P. Senopati Bantul Hospital. The  treatment group will be given a hospital standard diet and given extra egg white juice 3x/day for 7 consecutive days. The control group was given a hospital standard diet and extra egg white as a side dish. Data were analyzed using t-test with 95% CI.Results: The mean of albumin increase in the treatment group was higher (0.5215 ± 1.6852) than the control group (0.007 ± 0.4522) (p=0.001). The mean of Hb increase in treatment group (1.685 ± 1.5898) was higher than the control group (0.929 ± 2.3169), but not statistically significant (p=0.163).Conclusion: Giving extra egg white juice 3x/day for 7 days it can be used as an alternative to high-protein diets, they are inexpensive (low cost) and easily administered to the patient, and can increase in albumin levels.
Perbedaan asupan energi, zat gizi makro dan mikro pada mahasiswa S2 IKM reguler yang stress Ice Yolanda Puri; Pernodjo Dahlan; Ita Paramastri
Jurnal Gizi Klinik Indonesia Vol 3, No 1 (2006): Juli
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.17422

Abstract

Background: In general, sufferers of stress lose appetite, although sometimes some of them eat more than usual. If they lose appetite, there will be energy and protein deficiency. This condition will disrupt antibody so that they can get easily infected. Stress causes nutrition absorption disorder and then reduces antibody. Emotional and environmental stress will lose vitamin C as much as 2500 mg within a short period. Another bad impact is reducing supply of vitamin B12, vitamin C, calcium and zinc.Objective: To identify differences of energy, macronutrient (carbohydrate, protein, and fat) and micronutrient (vitamin C, vitamin B12, calcium and zinc) intake among postgraduate students of public health sciences (Health Policy Management and Service, Health Nutrition and Mother and Child Health Reproduction) with low, middle and high stress.Method: The study was an observational type which used a nested case control design. It used a quantitative approach to analyze stress and intake of energy, macronutrient (carbohydrate, protein and fat) and micronutrient (vitamin C, B12, calcium and zinc). Subject of the study were as many as 34 postgraduate students of public health sciences of Gadjah Mada University of academic year 2004/2005. Data of respondents’ identity, intake of protein, macronutrient and micronutrient and stress were achieved directly through questionnaires. Intake data were taken from food record form with multiple record 4 x 24 methods which were collected for a month to represent all days. Anthropometric data used was body weight. Data of stress were collected using stress questionnaires. Intake data analysis used NutriSurvey program. Anova test were used to identify differences of aver-age consumption of macro and micro nutrients.Result: There was no difference of macronutrient and micro-nutrient intake with low, middle and high stress. Result of Anova analysis showed that there was no significant difference be-tween intake of macronutrient and micronutrient and level of stress.Conclusion: There was no significant difference of macronutrient and micronutrient intake with low, middle and high level of stress among postgraduate students of public health sciences of academic year 2004/2005.
Perubahan parameter biologik jaringan kanker payudara mencit akibat pemberian isoflavon tempe Siti Harnina Bintari; Siti Fatimah Moeis; Sarjadi Sarjadi
Jurnal Gizi Klinik Indonesia Vol 9, No 4 (2013): April
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.18368

Abstract

Background: Cancer is severe diseases caused by the changing of deoxyribonucleic acid (DNA) structure. Women who consume soy products have a lower risk for breast cancer, but it cannot be explained the kind of biomolecular aspects of soy product which gives this role.Objective: The aim of this research was to analyze the biological parameter changing of AgNORs, p53, Cas-3 and Bcl-2 in mouse (Mus musculus) C3H strain with breast cancer, as the impact of injecting isoflavone of tempeh.Method: The laboratory experimental research was done by posttest only randomized controlled group design. Subject of study were 18 mice (Mus musculus) C3H strain that were divided into 3 groups, each of which consists of 6 mice. The first group, the control (K), was not injected by isoflavone, while the second group (P1) and the third group (P2) were injected by 1.000 mg and 10.000 mg of tempeh isoflavone/kg diet/day, respectively. All groups were given the transplanted breast cancer cells. AgNORs parameters were selected to determine the level of proliferation and p53 parameters, Cas-3 and Bcl-2 to determine the appearance of apoptosis. Data were analyzed by using Manova and discriminant test for each parameter of cell proliferation.Results: Concentration of isoflavones supplementation with 1,000 and 10,000 mg / kgdiet / day gave effect to the reduction of AgNORs blots, expression of p53 and Cas-3 and increased expression of Bcl-2 in group P1 and P2 compared with control group, as indicated by high statistical values (p=0.000) between both groups or within the group. Results of discriminant test showed that Bcl-2 and AgNORs had dominant role in increased apoptosis and inhibition of cancer cell proliferation in experimental animal.Conclusion: Tempeh isoflavones can be used as a biological parameter change agent that marks the proliferation and apoptosis of mice (Mus musculus) C3H strain towards the normal cell cycle progression.
Pelaksanaan asuhan gizi dengan pendekatan terapi gizi medis (TGM) berpengaruh terhadap asupan gizi pasien di RSUD Kota Bekasi Ika Yuliati C; I Made Alit Gunawan; R Dwi Budinigsari
Jurnal Gizi Klinik Indonesia Vol 5, No 1 (2008): Juli
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.17508

Abstract

Background: Medical nutrition therapy (MNT) is one of nutrition care models which focuses on integrated patient management involving active participation of doctors, nutritionists, nurses, and other professions within nutrition care team. An indicator of success in nutrition intervention is nutrition intake. Bekasi Municipal Hospital has not implemented integrated nutrition care within a team. The result of monitoring and evaluation during the first quarter of 2006 showed that average patient nutrition intake was only 65-70% (inadequate).Objective: To identify the influence of nutrition care implementation using MNT approach to nutrition intake and length of stay at Bekasi Municipal Hospital.Method: The study was quaci-experimental which used static-group comparison. Samples were patients hospitalized at internal medicine ward of class VIP, 1, 2, and 3. Data obtained consisted of conventional nutrition care and MNT, data of nutrition intake using Comstock visual and 24 hour recall methods. T-test and Mann Whitney statistical test were used to analyze the influence of types of nutrition care to nutrition intake.Results: Average percentage of total nutrition intake of hospital food and outside hospital food sample with MNT nutrition care was better than conventional nutrition care. Total nutrition intake was 91.71% for energy, 92.12% for protein, 111.83% for fat, and 85.41% for carbohydrate. The result was significant for energy intake (p<0.05). Nutrition intake of sample hospital was 86.08% for energy, 88.91% for protein, 108.55% for fat, and 78.91% for carbohydrate. Nutrition intake of outside hospital was 21.94% for energy, 13.77% for protein, 12.22% for fat, and 35.43% for carbohydrate. They were not significant statistically.Conclusion: There was difference in nutrition intake between samples with MNT and conventional nutrition care. Nutrition intake of samples with MNT was better than conventional nutrition care and statistically significant (p<0.05).
Prevalensi kasus dehidrasi pada mahasiswa Universitas Gadjah Mada Mirza Hapsari Sakti Titis Penggalih; Zaenal Mutaqien Sofro; Eka Roshifita Rizqi; Yuniko Fajri
Jurnal Gizi Klinik Indonesia Vol 11, No 2 (2014): Oktober
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.19008

Abstract

Background: Involuntary dehydration can lead to body function of disturbances. Orthostatic measurements were performed to determine the involuntary dehydration caused by orthostatic hypotension. Dehydration is also influenced by the high level of activity and ambient temperature without sufficient fluid intake. Students are prone to dehydration due to their activity, they have to be well hydrated to achieve their academic and nonacademic performances.Objective: To determine the prevalence of dehydration among students of Gadjah Mada University.Method: An observational study with the cross-sectional design were conducted and involved 274 students of Gadjah Mada University. Orthostatic measurement and interview of their activity and smoking habit were performed on all subjects.Results: The prevalence of dehydration were 60.9%. Type of activity and smoking habit did not affect the hydration status.Conclusion: Dehydration prevalence rate is still high on the students. As almost all students are dehydrated, then the factors that should be able to distinguish the condition of dehydration such as a type of activity and smoking habit, seems to give no effect in this study.
Asupan zat gizi, status gizi dan motivasi serta hubungannya dengan produktivitas pekerja perempuan pada bagian pencetakan di Pabrik Bakpia Pathuk 25 Yogyakarta Rina Kusriyana; Siti Helmyati; R Dwi Budiningsari
Jurnal Gizi Klinik Indonesia Vol 7, No 1 (2010): Juli
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.17614

Abstract

Background: Employees’ productivity is closely related with nutritional condition. Nutritional condition can be physically assessed by determining nutrition status. One’s nutrition status is directly influenced by nutrient intake. However, health and nutrition status of an employee in general have not got proper attention that lead to decreasing productivity. Productivity is not only influenced by nutrition status but also by psychological factor that involves motivation.Objectives: To identify association between nutrient intake, nutrition status and motivation and productivity of female workers at production department of Bakpia Pathuk 25 Factory Yogyakarta.Method: The study was a survey that used cross sectional design. Subject of the study were female workers at production department as many as 40 people taken through proportional stratified random sampling technique. Data of subject assessed were nutrient intake (energy, carbohydrate, fat, protein, and Fe), nutrition status, motivation, and productivity. Nutrient intake was assessed using food recall 24 hours within 4 days, nutrition status was specified using anthropometric approach using body mass index (weight/height), motivation was assessed through motivation questionnaire and productivity through quantity of production (raw bakpia) produced by the worker at a time observation (44 minutes for workers at crust production and 1 hour for workers at filing department) within 3 times observation.Result: The result of linear regression analysis showed that association between nutrient intake (energy, carbohydrate, fat, protein and Fe), nutrition status and productivity was r<0.25 and p>0.05 whereas between motivation and productivity was r=0.901; R2= 0.812; and p=0.000 for variables of wages, intake of energy, Fe and motivation and productivity.Conclusion: There was no significant association between nutrient intake (energy, carbohydrate, fat, protein and Fe) and nutrition status and productivity; there was signifiant association between motivation and productivity. Concurrently only motivation had significant association with productivity.
Potensi glukomanan pada tepung porang sebagai agen anti-obesitas pada tikus dengan induksi diet tinggi lemak Choirun Nissa; Indah Juliana Madjid
Jurnal Gizi Klinik Indonesia Vol 13, No 1 (2016): Juli
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.22751

Abstract

Background: Epidemiological studies indicate that the global prevalence of obesity has increased. Glucomannan is a water-soluble, non-starch polysaccharide, known as soluble fiber. Glucomannan has the ability to lower blood cholesterol levels and blood glucose levels, weight loss and affects the activity of intestinal and immune system function.Objective: The purpose of this study was to determine the effect of glucomannan derived from konjac flour as antiobesity agent on body weight and food intake in rats induced by high-fat diet.Method: Research was conducted in the Pharmacology Laboratory, Faculty of Medicine, University of Brawijaya. This study uses a true experimental research design. Animals were divided into six groups, normal group, normal + konjac flour, obese group, obese group + konjac flour 100 mg/kg body weight, obese group + konjac flour 200 mg/kg body weight, obese group + konjac flour 400 mg/kg.Results: Based on One-way ANOVA test, there is a significant difference (p: 0.000) on body weight after konjac flour treatment in all groups. Based on the Kruskal-Wallis test, there is a difference in food intake in various groups (p = 0.000).Conclusion: It can be concluded that glucomannan derived from konjac flour can decrease body weight and food intake in rats induced by high-fat diet. 
Pangan yang difortifikasi zat gizi mikro pada ibu hamil meningkatkan perkembangan motorik bayi Bernatal Saragih; Hidayat Syarief; Hadi Riyadi; Amini Nasoetion
Jurnal Gizi Klinik Indonesia Vol 9, No 1 (2012): Juli
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.15365

Abstract

Background: Many factors infl uence the growth and development of an infant but nutrition was undeniably one of the most important factors. One way to improve the nutritional status of infants was by providing supplementary foods fortifi ed with multiple micronutrients to mothers during pregnancy. Nutritional interventions during pregnancy provided better nutrient reserves for mothers and fetus.Objective: To analyze the impact of multi micronutrient-fortifi ed supplementary foods provision in pregnant mothers on motor development and anemia status of infants in three sub-districts of Bogor District namely: Leuwiliang, Leuwisadeng and Ciampea.Method: A total of 120 infants were followed up in a prospective cohort study. The subjects were divided into three groups, i.e: 40 infants in fortifi ed group (pregnant mothers received supplementary foods (vermicelli, milk and biscuit) fortifi ed with multi-nutrients i.e. iron, iodine, zinc, folic acid, vitamin C and vitamin A), 40 infants in non-fortifi ed groups (pregnant mothers received non fortifi ed foods) and 40 infants in the control groups (pregnant mothers did not receive any supplementary foods). Motor development was measured by methods developed by the Ministry of Health, Republic of Indonesia. Hb was measured by Cyanmethemoglobin method. Ancova and linear logistic regression were used to analyze the data.Results: Provision of multi micronutrient-fortifi ed supplementary foods in pregnant mothers substantially improves infant’s motor development (77% better than other groups). In addition, supplementation of multi micronutrient-fortifi ed foods in pregnant mothers reduced the rate of hemoglobin and hematocrit decline in infants up to the age of 6 months. There were no infants aged 6 months with Hb < 90 g / L in the fortifi ed group, while in the non-fortifi ed group and control group the prevalence of anemia was 8.3% and 11.11%, respectively.Conclusion: Provision of multi micronutrient-fortifi ed supplementary foods in pregnant mothers improved infant’s motor development.

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