This study examined the prevalence of probable post-traumatic stress disorder (PTSD) and depressive symptoms among Indonesian adults during a public health emergency and investigated whether sleep duration and home quarantine duration mediated the association between crisis-related exposure and psychological distress. A cross-sectional online survey was conducted with 500 Indonesian adults who had experienced health-related home quarantine. PTSD symptoms were measured using the PTSD Checklist–Civilian Version, and depressive symptoms were assessed using the Patient Health Questionnaire-9. Hierarchical regression and mediation analyses were performed. Results showed that 57.8% of participants met the screening cutoff for probable PTSD, while 54.4% met the cutoff for probable depressive symptoms. Distressing media exposure was associated with both outcomes. Sleep duration and home quarantine duration partially mediated the associations between crisis-related exposure and PTSD and depressive symptoms. These findings highlight the importance of media regulation, sleep promotion, and psychological support during future public health emergencies.
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