Biology, Medicine, & Natural Product Chemistry
Vol 15, No 1 (2026)

Fractionation and Antibacterial Activity of the Methanol Extract of White Champaka Flowers (Magnolia alba (DC.) Figlar)

Ulil Amna (Universitas Samudra)
Irma Setia Fitri (Universitas Samudra)
Halimatussakdiah Halimatussakdiah (Universitas Samudra)
Mastura Mastura (Universitas Samudra)
Syarifah Yanti Astryna (Universitas Ubudiyah Indonesia)



Article Info

Publish Date
22 Aug 2026

Abstract

Research on fractionation and antibacterial activity test of methanol extract of cempaka putih (Magnolia alba (DC.) Figlar) flower was conducted. This study aimed to investigate the class of chemical compounds contained in the methanol extract of cempaka putih (M. alba (DC.) Figlar) flowers and to test the antibacterial activity of the methanol extract of M. alba (DC.) Figlar flowers against Staphylococcus aureus and Escherichia coli bacteria. Based on the results of phytochemical screening, these showed that the methanol extract and its fractions contained secondary metabolites of alkaloid, terpenoids, steroids, saponins, flavonoids, phenols and tannins. Testing for antibacterial activity was carried out by the Kirby-Bauer method (agar diffusion) against S. aureus and E. coli bacteria, at concentrations of 5, 10, 20 and 40 ppm. The antibacterial activity test showed that the methanol extract gave moderate activity against E. coli and fraction A gave moderate activity against S. aureus. While other fractions showed weak activities against both bacteria.

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Journal Info

Abbrev

BIOMEDICH

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

Description

BIOLOGY, MEDICINE, & NATURAL PRODUCT CHEMISTRY, this journal is published to attract and disseminate innovative and expert findings in the fields of plant, animal, and microorganism secondary metabolite, and also the effect of natural product on biological system as a reference source for ...