Journal of Midwifery and Health Science of Sultan Agung
Vol. 5 No. 2 (2026): JMHSA

Hemoglobin Profile, Leukocyte Differential Count, and Red Blood Cell Distribution Width in Drug-Resistant Tuberculosis Patients Before and After Antituberculosis Treatment

Alma Devara (Universitas Mulawarman)
Marwan Marwan (Universitas Mulawarman)
Hoopmen Hoopmen (Universitas Mulawarman)



Article Info

Publish Date
25 Aug 2026

Abstract

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. Indonesia ranks second globally in TB cases, contributing approximately 10% of the global burden. This condition is further complicated by Drug-Resistant Tuberculosis (TB RO), in which patients develop resistance to first-line antibiotics. This study aims to analyze hemoglobin (Hb) profiles, leukocyte differential counts, and Red Blood Cell Distribution Width (RDW-CV) in TB RO patients before and after antituberculosis treatment (OAT) at RSUD Abdoel Wahab Sjahranie Samarinda. This study employed a descriptive observational design with a cross-sectional approach. Data were obtained from medical records involving 16 patients who met the inclusion criteria. The results showed that most patients were aged 36–45 years (50%), male (68.75%), received a short-term treatment regimen (75%), and underwent treatment for nine months (37.5%). Anemia was found in 75% of patients, while 68.8% had normal RDW-CV levels. Most leukocyte differential parameters were within normal ranges, including eosinophils (87.5%), neutrophils (100%), lymphocytes (56.3%), monocytes (68.8%), and basophils (100%). Most parameters improved after treatment. In conclusion, monitoring Hb, RDW-CV, and leukocyte differential counts may help identify hematological changes before and after treatment and support early detection of potential complications and treatment failure.

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Journal Info

Abbrev

jmhsa

Publisher

Subject

Health Professions Medicine & Pharmacology Nursing Public Health

Description

This journal accepts and publishes academic articles focusing on theory, methods, and applications in Midwifery Maternal Newborn Child and Adolescent Health Womens health Reproductive health Nursing Public ...