Reproductive health knowledge and attitudes in adolescents remain a major public health concern, particularly in developing countries where access to comprehensive sexuality education is still limited. This systematic literature review (SLR) aims to identify and analyze the factors that influence the level of knowledge and attitudes of adolescents toward reproductive health. Literature searches were conducted using Google Scholar, PubMed, ScienceDirect, and Scopus databases using keywords such as "reproductive health knowledge adolescents", "student attitude reproductive health", and "factors influencing adolescent reproductive health". Inclusion criteria included articles published between 2015 and 2024, focusing on adolescent or student subjects aged 10–19 years, and reporting quantitative, qualitative, or mixed-method results. After a systematic screening and eligibility process following the PRISMA framework, a total of 15 articles were included for final analysis. The results identified four major categories of influencing factors: (1) educational factors, including school curriculum quality, teacher competence, and peer education programs; (2) family factors, including parent-adolescent communication quality and parental supervision; (3) media and technology factors, including social media use and digital literacy; and (4) socio-cultural factors, including social norms, cultural taboos, and peer pressure. Educational and family communication factors emerged as the most consistently influential across studies. Gaps were identified in research focusing on the Indonesian context and studies specifically targeting attitudes rather than knowledge. These findings have implications for the design of school-based reproductive health programs that are culturally sensitive and family-inclusive.
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