Hypertensive heart disease is a significant cause of morbidity and mortality globally that tends to increase with age. The high prevalence of uncontrolled blood pressure leads to an increase in the occurrence of HHD, so the optimal use of antihypertensive drugs is essential in preventing and controlling HHD. This study aims to determine the drug utilization evaluation of antihypertensives in elderly hypertensive heart disease patients at the polyclinic of RSUP Dr. Mohammad Hoesin Palembang, Period of January - June 2023. This research is a descriptive study in the form of a drug utilization evaluation, with a sample of 157 patients. Data were collected using the total sampling technique, using secondary data from patient medical records. The most common therapeutic regimen was a combination of 2 antihypertensive drugs (42.7%), with the most frequent drug class combination being CCB + ARB (21.7%). Based on the PERHI 2021 recommendations, 97.3% of drugs were at the appropriate dose, and 88.8% were administered at the appropriate frequency of administration. Most drug combinations, dosages, and frequencies of antihypertensives administered to patients were appropriate, with the most common combination being two drugs: CCB and ARB.
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