Enterprise supply chains spanning ERP, WMS, TMS, MES, B2B/EDI platforms, and IoT event sources face a fundamental integration challenge that becomes more critical as operations move toward autonomous decision-making. Autonomous supply chain systems require data that are consistent, current, semantically aligned, and resilient to integration failures, whereas conventional enterprise architectures were largely designed for human-mediated workflows in which planners and operators could identify and correct inconsistencies before they propagated. This study proposes the Intelligent Enterprise Integration Architecture (IEIA), a framework designed to establish an integration foundation for autonomous supply chain operations. IEIA is structured around four mutually reinforcing principles: API-led connectivity, canonical data model governance, event-driven orchestration, and fault-tolerant pipeline design. The framework addresses four integration failure modes that can compromise autonomous decisions: silent data corruption, cascade pipeline failure, duplicate message processing, and schema drift. API-led connectivity establishes stable and versioned interfaces across heterogeneous enterprise systems, while canonical data governance provides semantic consistency across ERP, WMS, TMS, B2B/EDI, and IoT data sources. Event-driven orchestration improves data freshness for high-frequency operational signals while preserving centralized coordination for transaction-dependent processes. Fault-tolerant pipeline design incorporates idempotency, deduplication, dead-letter queues, and integration observability to support reliable processing under distributed-system failures. The framework is further mapped to Oracle Integration Cloud (OIC) capabilities and a phased implementation strategy is proposed to support progressive adoption without requiring immediate replacement of existing enterprise systems. The study demonstrates that autonomous supply chain capability is constrained not only by the intelligence of decision algorithms but also by the architectural reliability of the integration layer supplying their operational data. IEIA therefore provides a practical architectural foundation for scalable, resilient, and progressively autonomous enterprise supply chain operations
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