<![CDATA[Diabetes is a chronic condition that cannot be cured, but it can be managed using synthetic or herbal hypoglycaemic agents. Herbal plants containing phytochemicals serve as an alternative treatment for diabetes due to their lower incidence of side effects. Bhee fruit (Melastoma malabathricum L.) is rich in antioxidants and has potential as a hypoglycaemic agent. This study aims to identify the phytochemical content qualitatively and quantitatively, and to test the effect of bhee fruit extract on blood glucose levels in a diabetic mice model. Qualitative identification was carried out using water, ethanol and methanol as solvents. Quantitative analysis was performed using UV-Vis spectrophotometry and gravimetry. The in vivo test involved 24 mice divided into six groups: normal control, metformin control, diabetic control, and three treatment groups with extract doses of 100, 200, and 400 mg/kg body weight over 28 days. The results showed that the aqueous solvent extracted the highest amount of bioactive components, including steroids, terpenoids, saponins, flavonoids, phenols and tannin. Furthermore, administration of the aqueous extract significantly reduced blood glucose levels in diabetic mice, with the highest reduction at 400 mg/kg body weight (p<0.05). In conclusion, the aqueous extract of bhee fruit is effective as a hypoglycaemic agent in diabetic mice. Keyword: Antioxidants; Alloxan; Hyperglycemia; Secondary metabolites.]]>
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