Schizophrenia is a chronic mental disorder that negatively affects individuals' cognitive, emotional, and social functioning, often resulting in a diminished quality of life. While pharmacological interventions remain the primary treatment, complementary spiritual therapies have gained interest for their holistic benefits. This study aimed to evaluate the effect of Gayatri mantra spiritual treatment on the quality of life among patients with schizophrenia. A one-group pretest-posttest design was used, involving 22 participants selected through purposive sampling at a provincial mental hospital in Bali. Participants received daily Gayatri mantra sessions for three consecutive weeks. The World Health Organization Quality of Life-BREF (WHOQOL-BREF) instrument was used to assess outcomes, and data were analyzed using the Wilcoxon signed-rank test. The findings showed a significant improvement in quality of life following the intervention. This study highlights the potential value of integrating spiritual practices into nursing care as a complementary therapeutic strategy to support mental health recovery and enhance overall patient well-being.
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