Background: Performance is the result of a person's ability to complete tasks and responsibilities competitively. There are many factors that affect a person's performance, each of which affects their own performance. This study aims to analyze the variables that affect the performance of health center employees. Subjects and Method: This study is an observational analytical study with a cross-sectional design. This research was conducted on 11 health centers in Metro City, Lampung in March-April 2024. A sample of 200 health center employees was selected by simple random sampling. The dependent variable in this study is the performance of health center employees. The independent variables in the study were age, training, incentives, motivation, leadership perceptions, and the strata of the health center. Data collection was carried out using a questionnaire and analyzed by multiple linear regression. Results: Employee performance in service at the health center was influenced by age (b= -0.01; CI 95%= -0.01 to -0.02; p= 0.008), training (b=1.08; CI 95%= 1.03 to 1.13; p< 0.001), incentives (b= 1.02; CI 95%= 0.98 to 1.05; p< 0.001), motivation (b= 1.16; CI 95%= 1.08 to 1.22; p<0.001), leadership perception (b= 0.98; CI 95%= 0.93 to 1.03; p<0.001), and the strata of the health center (b= 0.33; CI 95%= 0.10 to 0.54; p=0.003). Conclusion: The performance of health center employees is positively influenced by age, training, incentives, motivation, leadership perception, and strata of the health center.
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