Background: Health is a very complex field because it focuses on healthcare providers. The quality of healthcare can be determined through the job satisfaction of healthcare workers. Factors that can affect the job satisfaction of healthcare workers can be assessed based on marital status, working conditions, education, gender, and age. The purpose of this study was to estimate the effect of marital status, working conditions, education, gender, and age on job satisfaction among healthcare workers. Subjects and Method: A meta-analysis study was conducted in accordance with the PRISMA flow chart and PICO model. Population: healthcare workers. Intervention: female, >30 years old, bachelor's degree, single, and good working environment. Comparison: male, <30 years old, diploma, married, and poor working environment. Outcome: job satisfaction. Data were obtained from the Google Scholar, PubMed, BMC, ScienceDirect, Elsevier, and Springer Link databases. The keywords used were “gender” AND “age” AND ‘education’ AND “marital status” AND “work environment” AND “job satisfaction” AND “health workers” AND “cross-sectional” AND “aOR”. Data analysis was performed using Review Manager 5.3 software. Results: This meta-analysis included 12 cross-sectional studies from Myanmar and Ethiopia. The sample size was 3,962 health workers. Marital status (aOR= 1.43; 95% CI= 1.03 to 2.00; p= 0.003) and good working conditions (aOR= 1.55; 95%CI= 1.18 to 2.04; p= 0.002) significantly increased job satisfaction among health workers. Bachelor's degree (aOR= 1.51; 95% CI= 0.53 to 4.83; p= 0.400), female gender (aOR= 1.34; 95% CI= 0.87 to 2.05; p= 0.180), and age >30 years (aOR= 1.81; 95% CI= 0.81 to 4.09; p= 0.150) increased job satisfaction among healthcare workers but were not statistically significant. Conclusion: Marital status, work environment conditions, education level, gender, and age affect job satisfaction in health workers.
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