Acne is a common skin disorder that is often associated with the bacterium Propionibacterium acnes. Centella asiatica and Jasminum sambac contain bioactive compounds with potential antibacterial properties. This study aimed to evaluate the physicochemical quality and antibacterial activity of traditional face masks formulated from Centella asiatica, Jasminum sambac, and their combinations against P. acnes. The evaluations included organoleptic properties, homogeneity, pH, spreadability, adhesiveness, drying time, stability, irritation, and in vitro antibacterial activity. This research employed five test formulations and two positive controls, comprising a commercially available anti-acne medication and a commercially available traditional anti-acne mask. The results showed that Formula 1, containing 30% Centella asiatica, 40% rice, and 30% oat, fulfilled all physicochemical quality requirements. However, the formulation did not demonstrate antibacterial activity against P. acnes. Further studies regarding its potential role in acne treatment are needed to support the development and application of this traditional face mask product.
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