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All Journal Journal Pharmaceutical Science and Application (JPSA) Jurnal Kajian Bali Jurnal Ilmu Kefarmasian Indonesia Jurnal Ilmiah Medicamento Sevanam: Jurnal Pengabdian Masyarakat Jurnal Yoga Dan Kesehatan
I Gusti Agung Ayu Kartika
Yoga And Health Study Program, Faculty Of Brahma Widya, Universitas Hindu Negeri I Gusti Bagus Sugriwa Denpasar, North Denpasar, Bali 80237, Indonesia
Religion Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences

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ANTI-INFLAMMATORY ACTIVITIES OF PEPEROMIA PELLUCIDA [L.] KUNTH.: A REVIEW I Gusti Agung Ayu Kartika; Ni Ketut Sinarsih; Ni Made Dwi Mara Widyani Nayaka
Journal Pharmaceutical Science and Application Vol 4 No 1 (2022): Journal Pharmaceutical Science and Application
Publisher : Departement of Pharmacy, Faculty of Mathematic and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JPSA.2022.v04.i01.p06

Abstract

Background: Inflammation is a natural body response, but when it reaches the systemic chronic inflammation stage, it can cause more dangerous complications. Many natural ingredients have been developed as anti-inflammatory agents. One of them is sirih bumi (Peperomia pellucida [L.] Kunth). Objective: This study aims to summarize and examine the research results related to the anti-inflammatory activity of the sirih bumi. Methods: Research articles were collected from various online databases such as Google Scholar, Google, Medline, Pubmed, and Science Direct. Inclusion and exclusion criteria were applied to obtain original research articles relevant to the desired topic, published in the last ten years, the full text was accessible, and the research methods and results were well explained and valid. Results: In total, only six articles are eligible to be discussed. The research was conducted in Indonesia, Nigeria, and Malaysia. In vitro and in vivo methods with various models and parameters were used to test the anti-inflammatory activity. All parts of the plant are proven to have anti-inflammatory effects that can be presented in extracts or herbal teas. The activity of sirih bumi is determined by the dose or concentration of administration, processing process, and harvest time. The combination with other samples must be reconsidered to maintain the desired anti-inflammatory effect. Conclusion: Anti-inflammatory activity of sirih bumi has been proven through various studies. The development of the sirih bumi product is expected to help handle inflammation and other diseases related to inflammation. Keywords : peperomia pellucida, inflammation, extract, tea
Kombinasi Yoga dan Herbal dalam Pengobatan Beserta Efektivitasnya I Gusti Agung Ayu Kartika; Made Krisna Adi Jaya
Jurnal Yoga dan Kesehatan Vol 5 No 2 (2022): Volume 5 No. 2 Tahun 2022
Publisher : UHN IGB Sugriwa Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (699.171 KB) | DOI: 10.25078/jyk.v5i2.1896

Abstract

Yoga is often combined with other types of therapy to maximize the patient's treatment. Combinations of yoga and herbs is one of the possible combinations. This study aims to summarize and review research results related to the combination of yoga and herbs. Research articles are collected from various online databases such as Google Scholar, Google, Medline, Pubmed, and Science Direct. Inclusion and exclusion criteria were applied to obtain clinical research articles that were original, relevant to the topic of interest, published in the last 10 years, full text accessible, also methods and results were described well and valid. In total there are only 5 articles that qualify for discussion. The research was conducted in Indonesia and India. The herbs were used in inhalation and oral forms. Indications for the use of a combination of yoga and herbs are reducing dismenorrhea pain, cronic joint pain, helping treat type 2 diabetes mellitus, hypertension, and improving sleep quality. The combination of yoga and herbs is still not widely applied and studied. It opens up great opportunities for further research.
Profil Fitokimia dan Aktivitas Antibakteri dari Massoia aromatic Becc., Acorus calamus L., dan Allium sativum L. terhadap Bakteri Penyebab Rinosinusitis Sugata, I Made; Darmo Suputra, I Kadek; Emy Suryanti, Putu; Juniartha, Made G.; Kartika, I Gusti Agung Ayu
Jurnal Ilmiah Medicamento Vol 9 No 2 (2023): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v9i2.5961

Abstract

Triketuka, an herb with multiple therapeutic activities, is featured in Balinese medicinal texts. This herb is composed of Massoia aromatic Becc. (masoyi), Acorus calamus L. (dringo), and Allium sativum L. (garlic). The antibacterial activity of these ingredients against bacteria causing rhinosinusitis has not been fully evaluated. Hence, this study seeks to determine the potential of these three components, especially with regards to their effectiveness against rhinosinusitis. In this research, an in vitro antibacterial test was conducted against Streptococcus aureus, Staphylococcus epidermidis, Escherichia coli, and Pseudomonas aeruginosa. The phytochemical profile of each plant was determined using Liquid Chromatography-Mass Spectrometry. The Minimum Inhibitory Concentration value was determined by carrying out the antibacterial test via the microdilution method. The detected compounds were analyzed for their contributions through the prediction of activity spectra for biologically active substances (PASS) online and Antibac-Pred. As a result of the in vitro antibacterial test, the samples were found to have MIC > 4096 ppm against all bacteria except Massoia aromatic and Acorus calamus against Staphylococcus aureus in MIC 4096 ppm each. This discovery was further verified through PASS online and Antibac-Pred. The studies indicate that certain compounds found in the samples exhibit antibacterial activity, albeit with low efficacy against the tested bacteria. In conclusion, the plants exhibit low antibacterial potential against bacteria that cause rhinosinusitis. Further research on the combination of the three plants is required to enhance their antibacterial efficiency.
Pelatihan Kesehatan Kerja Kepada Pemangku Di Kota Denpasar Purnamawati, Dr. Made Sri Putri; I Made Dwitayasa; Wika, I Made; Ni Ketut; Dewi, Ni Made Umi Kartika; Wiguna, I Nyoman Agus Pradnya; Suputra, I Kadek Darmo; Diaris, Ni Made; Kartika, I Gusti Agung Ayu
Sevanam: Jurnal Pengabdian Masyarakat Vol 2 No 1 (2023): Maret
Publisher : Universitas Hindu Negeri I Gusti Bagus Sugriwa Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25078/sevanam.v2i1.2130

Abstract

Occupational health is very much needed by stakeholders because of the prevalence of infectious diseases due to the spread of globalization. Stakeholders are very vulnerable to disease transmission because they are face to face and even come into contact with the community. In addition, stakeholders need an understanding of religious knowledge because in general stakeholders carry out professions because of heredity so that they need to be given guidance so that they have an understanding of the function, meaning of the profession and ritual ceremonies. Community service carried out by the health yoga study program aims to provide guidance and training to stakeholders in Denpasar City both from the social, religious and health aspects so that stakeholders can follow modernity standards, especially in the health sector without losing the sanctity and meaning of religious ceremonies or yadnya. The implementation methods for this activity are method I (presentation), method II (demonstration), method III (demonstrations and distribution of materials/tools) and method IV (demonstration). The results of the evaluation at the end of this activity, there was a significant increase in knowledge of the participants with the average posttest score above 90 points. In general, the implementation of this service was well received by the participants and went smoothly. Obstacles such as the schedule of activities that clash with holy holidays and the limited space for the implementation can be overcome through good cooperation from all parties. During the service, it was found that the enthusiasm of the participants to deepen the teachings of Hinduism and knowledge related to health was very high.
Edukasi Perilaku CERDIK Sebagai Upaya Pencegahan Dini Penyakit Tidak Menular Wiguna, I Nyoman Agus Pradnya; Diaris, Ni Made; Suputra, I Kadek Darmo; Dewi, Ni Made Umi Kartika; Apsari, Dewi Puspita; Sinarsih, Ni Ketut; Kartika, I Gusti Agung Ayu; Juniartha, Made G.
Sevanam: Jurnal Pengabdian Masyarakat Vol 3 No 1 (2024): Maret
Publisher : Universitas Hindu Negeri I Gusti Bagus Sugriwa Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25078/sevanam.v3i1.3596

Abstract

Currently, Indonesia is not only bearing the burden of Communicable Diseases (PM) but also the burden of Non-Communicable Diseases (PTM). One of the strategies in the guidelines for non-communicable diseases management by the Prevention and Control Directorate of Non-Communicable Diseases of the Republic of Indonesia Health Ministry in 2019 is to carry out promotive, preventive, curative, rehabilitative and palliative actions as a whole , one of which is with the CERDIK principle. CERDIK behavior is a necessary behavior to prevent various kinds of non-communicable diseases. The behavior in question is regular health checks, getting rid of cigarette smoke, diligent physical activity/exercise, and a healthy and balanced diet. Therefore, Lecturers in the Yoga and Health Study Program at I Gusti Bagus Sugriwa Denpasar State Hindu University carried out community service activities by providing CERDIK behavior education with the target of activities for students at the Bali Kresna Medika Health Vocational High School (SMK). the number of participants were 32 people. The implementation method for this activity was to provide CERDIK material, yoga exercises, and physical measurements which were carried out in 5 meetings. In general, the implementation of activities ran smoothly. The success of the activity is was measured by a questionnaire. The results showed that there was an increase in participants' knowledge regarding CERDIK, namely from the category of knowledge that was quite good to very good. In the future, it is hoped that this activity can be carried out with broader targets and scope.
Penataan dan Inventarisasi Tanaman Obat di UPTD Puskesmas III Dinas Kesehatan Kecamatan Denpasar Selatan Setyawan Guna Dharma; Ayu Nilam Tresna Dewi; Anak Agung Ketut Sri Trisna Dewi Widhiani; Nyoman Eva Sri Wahyuni; I Gusti Agung Sri Astuti; Putu Judy Satyawati Sudarmo; I Gusti Agung Ayu Kartika
Sevanam: Jurnal Pengabdian Masyarakat Vol 3 No 2 (2024): September
Publisher : Universitas Hindu Negeri I Gusti Bagus Sugriwa Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25078/sevanam.v3i2.3827

Abstract

Puskesmas as a health facility that is easily accessible to the community, of course, is a forum in promoting, especially introducing family medicinal plants (TOGA) that have been used for generations as an alternative treatment. Public understanding related to Family Medicinal Plants (TOGA) through the health center is still very minimal, therefore this community service is carried out on the basis of these problems through structuring and inventorying plants with medicinal properties at the UPTD Puskesmas III Health Office of the South Denpasar District Health Office. This community service team consists of 3 people, namely 1 lecturer and 2 students. The method used in this service includes 3 stages, namely: the preparation stage, starting with the submission of applications and discussions regarding the schedule and accompanied by conducting a survey of the location of the toga planting. Furthermore, the implementation stage begins with the cleaning of the planting area, planting new types of medicinal plants, plant care, making toga nameplates, and ending with the submission and installation of toga nameplates. there are 49 nameplates of medicinal plants along with scientific names and efficacy installed. The last stage is the preparation of a report that contains details about this community service activity.
Pelatihan Pijat Tradisional dalam Pengatasan Stunting di Puskesmas 2 Blahbatuh, Gianyar Anton, Sri Sulistyawati; Dewi, Ni Made Umi Kartika; Diaris, Ni Made; Sinarsih, Ni Ketut; Kartika, I Gusti Agung Ayu; Wiguna, I Nyoman Agus Pradnya; Suputra, I Kadek Darmo; Ariani, Ni Nyoman
Sevanam: Jurnal Pengabdian Masyarakat Vol 3 No 2 (2024): September
Publisher : Universitas Hindu Negeri I Gusti Bagus Sugriwa Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25078/sevanam.v3i2.4066

Abstract

Stunting is a major health issue affecting children's physical and cognitive development in Indonesia, particularly in Gianyar, Bali. This condition is often caused by inadequate nutrition and chronic infections in early childhood. This community service program aimed to provide training in traditional Balinese massage as a potential intervention to manage stunting. The method involved direct training and demonstration of massage techniques to the parents of 21 children aged 12-60 months with stunting together with their parents. Evaluation was conducted through measurements of height, weight, and other health parameters such as appetite and sleep quality. The results showed that traditional massage techniques effectively increased appetite and improved sleep quality. Approximately 80% of parents mastered the massage techniques and reported positive changes in their children. In conclusion, traditional Balinese massage holds promise as a culturally relevant intervention for stunting management and could be integrated into formal healthcare programs.
Pelaksanaan Metode Usada Tantra Bali Pada Ibu Hamil Dengan Emesis Gravidarum Di Praktik Mandiri Bidan Ni Luh Sri Rahayuni, A.Md.Keb. Ni luh Sri Rahayuni; I Wayan Redi; I Gusti Agung Ayu Kartika
Jurnal Yoga dan Kesehatan Vol 7 No 2 (2024)
Publisher : UHN IGB Sugriwa Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25078/jyk.v7i2.3503

Abstract

Salah satu keluhan yang dirasakan ibu hamil pada masa kehamilannya yaitu morning sickness atau emesis gravidarum. Pengobatanya masih enggunakam obat-obatan medis, akibat konsumsi secara terus menerus dapat menimbulkan efek samping. Dari permasalahan yang terjadi terhadap, peneliti tertarik untuk melakukan penelitian penyembuhan menggunakan metode Usada Tantra Bali untuk mengobati rasa mual muntah. Penelitian ini merupakan penelitian kualitatif, penelitian ini akan dilaksanakan dengan metode wawancara berupa anamnesa, observasi, literatur, dan dokumentasi. Metode pengobatan Usada Tantra pada ibu hamil dengan emesis gravidarum di PMB Ni Luh Sri Rahayuni mengunakan dua metoda saja yaitu energi dalam bentuk prana dan aksara serta penggunaan bahan mineral dalam bentuk air. Hal ini disebabkan kondisi spiritual dan keyakinan pasien yang ditangani atau diobati. Walaupun demikian hasil wawancara yang didapat bahwa metode pengobatan tersebut memiliki pengaruh terhadap penyembuhan dan kesehatan pada ibu hamil dengan emesis gravidarum.
Potensi Stabilisasi Membran Sel dari Ekstrak Berbeda Kepolaran Sirih Bumi (Peperomia pellucida [L.] Kunth) sebagai Agen Antiinflamasi I Gusti Agung Ayu Kartika; Suryani Suryani; Dwi Hadi Setya Palupi; I Ketut Adnyana
JURNAL ILMU KEFARMASIAN INDONESIA Vol 21 No 2 (2023): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v21i2.1440

Abstract

Sirih bumi (Peperomia pellucida [L.] Kunth.) is a medicinal herb. Anti-inflammatory activities are reported. These plant extracts have been shown to reduce inflammation in many studies, but it is unknown which extract works best. The objectives if this study were determine the extract that has the best anti-inflammatory activity from sirih bumi. The activity was assessed from the impact of stabilising red blood cell membranes in vitro. The research was then continued with a literature study on the chemical compounds containing the best extracts. To determine the prediction of the compound responsible for its activity and potency, several in silico tests were carried out, such as PASS online, Pre-ADMET online, and Protox II. The test results showed that the ethyl acetate extract at 200 g/mL concentration showed similar activity to aspirin at the same concentration. The activity of this extract increased with increasing concentration of the extract. Six compounds were reported to be isolated from this type of extract. Dillapiol and its derivative 6-allyl-5-methoxy-1,3-benzodioxol-4-ol are predicted to be compounds that have anti-inflammatory effects by inhibiting the membrane permeability mechanism of ethyl acetate extract. Ethyl acetate extract showed the best anti-inflammatory activity among the other type of extract from sirih bumi. Ethyl acetate extract is a type of extract with the best anti-inflammatory activity from sirih bumi.
Penyuluhan dan Penanaman Tanaman Obat Temulawak Di UPTD Puskesmas I Dinas Kesehatan Kecamatan Denpasar Utara Ayu Nilam Tresna Dewi; Setyawan Guna Dharma; I Gusti Agung Ayu Kartika
Sevanam: Jurnal Pengabdian Masyarakat Vol 4 No 1 (2025): Maret
Publisher : Universitas Hindu Negeri I Gusti Bagus Sugriwa Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25078/sevanam.v4i1.4778

Abstract

Temulawak (Curcuma xanthorrhiza) has been recognised as one of Indonesia’s leading medicinal plants due to its numerous health benefits, particularly in supporting liver function, boosting the immune system, and improving digestion. However, its utilisation in primary healthcare services remains limited due to a lack of knowledge among healthcare professionals regarding its benefits and active compounds, as well as proper cultivation and processing methods. This community service programme aimed to enhance the literacy and practical skills of healthcare personnel at UPTD Puskesmas I Denpasar Utara through educational sessions and hands-on training in temulawak cultivation and simplisia processing. The methodology involved pre-test and post-test assessments to measure participants' knowledge improvement. The evaluation results showed a significant increase, with 75% of participants achieving a perfect score after the training. Additionally, participants’ expectations regarding the benefits of the programme rose from 86.4% to 90%, while satisfaction with the training materials reached 91.36%. These findings indicate that the training effectively improved participants' knowledge and skills. Future programmes should focus on developing more interactive educational modules and conducting advanced practical sessions to ensure the sustainable application of acquired knowledge in primary healthcare services.
Co-Authors Anak Agung Ketut Sri Trisna Dewi Widhiani Anton, Sri Sulistyawati Ariani, Ni Nyoman Ayu Nilam Tresna Dewi Darmo Suputra, I Kadek Dewi Puspita Apsari Dewi, Ni Made Umi Kartika Diaris, Ni Made Dwi Hadi Setya Palupi Emy Suryanti, Putu I Gusti Agung Sri Astuti I Kadek Darmo Suputra, I Kadek Darmo I Ketut Adnyana I Made Dwitayasa I Made Sugata I Nyoman Agus Pradnya Wiguna I Wayan Redi Made G. Juniartha Made Krisna Adi Jaya Mahardika, Ida Bagus Putra Ni Ketut Ni Ketut Sinarsih Ni luh Sri Rahayuni Ni Made Dwi Mara Widyani Nayaka Nugraha, Iwan Saka Nyoman Eva Sri Wahyuni Purnamawati, Dr. Made Sri Putri Puspita Apsari , Dewi Putu Judy Satyawati Sudarmo Setyawan Guna Dharma Sinarsih, Ni Ketut Suryani Suryani Suryani Wartana Putra, I Gusti Ngurah Agung Windra Wika, I Made