Orthodontic mini-implants are widely used as temporary anchorage devices, and their biomechanical performance is influenced by implant material and applied orthodontic load. This study aimed to provide a standardized biomechanical comparison of commercially pure titanium (CP-Ti), Ti6Al4V alloy, and stainless steel 316L orthodontic mini-implants under different orthodontic loads using three-dimensional FEA. A standardized mini-implant was modelled and inserted into layered cortical-cancellous bone model. Simulations were performed in Autodesk Fusion version 2702.1.58. All materials were assumed to be homogeneous, isotropic, and linearly elastic. Lateral load of 2 N, 4 N, 6 N were applied to simulate orthodontic force. Von Mises stress, displacement, and contact pressure at the bone-implant interface were evaluated. Increasing the applied load from 2 N to 6 N produced a proportional increase in all evaluated mechanical parameters. At the maximum load of 6 N, the maximum Von Mises stress reached 38.67 MPa for CP-Ti, 37.90 MPa for Ti6Al4V, and 44.44 MPa for SS316L. The corresponding maximum displacement values were 1.5x10-5 mm, 1.5x10-5 mm, and 1.1x10-5 mm, respectively. Maximum contact pressure at the bone implant interface reached 55 MPa, 56 MPa and 52 MPa, respectively. Increasing orthodontic load increased stress, displacement and contact pressure regardless of the material. The results indicate that orthodontic loading magnitude has a greater influence on biomechanical response than implant material, although material properties affect stress and mechanical behavior. This study provides biomechanical evidence that may support material selection for orthodontic mini-implants and guide future experimental and clinical investigations.
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