Jurnal Riset Kefarmasian Indonesia
Vol. 8 No. 3 (2026): Jurnal Riset Kefarmasian Indonesia

Formulation and Evaluation of Antibacterial Activity of Roll-On Deodorant Based on Arab Jujube Leaf Extract (Ziziphus spina-christi L.) against Staphylococcus epidermidis

Muhammad Fauzi Anwar (STIKes KHAS Kempek, Cirebon, Jawa Barat, Indonesia)
Dwi Retno Sari (STIKes KHAS Kempek, Cirebon, Jawa Barat, Indonesia)
Indah Shaliha (STIKes KHAS Kempek, Cirebon, Jawa Barat, Indonesia)



Article Info

Publish Date
30 Sep 2026

Abstract

Body odor is a common issue that arises when excessive sweat interacts with microorganisms on the skin particularly Staphylococcus epidermidis. One practical and economical way to address this problem is through the use of deodorants, especially in roll on form. This study explores the potential of sidr tree leaves (Ziziphus spina-christi L.) as a natural ingredient for deodorant formulation, owing to their rich content of antibacterial compounds such as flavonoids, saponins, tannins, alkaloids, and terpenoids. The active compounds were extracted using maceration with 70% ethanol, chosen for its polarity and skin friendly properties. A phytochemical screening was conducted afterward to verify the presence of these bioactive compounds in the extract. The resulting extract was incorporated into roll-on deodorant formulations at three concentration levels: F1 (5 grams), F2 (10 grams), and F3 (20 grams). The formulations were evaluated for their physical characteristics, including organoleptic properties, pH, homogeneity, viscosity, and spreadability. Furthermore, antibacterial activity against Staphylococcus epidermidis was assessed using the disk diffusion method to determine the effectiveness of each formula.  

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Journal Info

Abbrev

jrki

Publisher

Subject

Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Description

JURNAL RISET KEFARMASIAN INDONESIA adalah jurnal yang diterbitkan online dan diterbitkan dalam bentuk cetak. Jurnal ini diterbitkan 3 kali dalam 1 tahun (Januari, Mei dan September) Jurnal ini diterbitkan oleh APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) Lingkup jurnal ini mencakup ...