Vitamedica: Jurnal Rumpun Kesehatan Umum
Vol. 4 No. 4 (2026): Oktober : VitaMedica : Jurnal Rumpun Kesehatan Umum

Analisis Korelasional Skor Child-Pugh dan lama Perdarahan pada Pasien yang Menerima Terapi Oktreotid di RSUP Dr.Kariadi

Anita Tri Widiati (Unknown)
Tri Murti Andayani (Unknown)
Woro Harjaningsih (Unknown)



Article Info

Publish Date
01 Oct 2026

Abstract

Gastrointestinal bleeding due to esophageal variceal rupture is a life-threatening complication of liver cirrhosis. Octreotide is widely used as a first-line pharmacological therapy to control bleeding. However, bleeding duration varies among individuals and may be correlated with liver functional reserve. This study aimed to analyze the correlation between Child-Pugh score, its constituent components, transfusion characteristics, and bleeding duration in liver cirrhosis patients receiving octreotide therapy at Dr. Kariadi Central Hospital. A cross-sectional analytical study was conducted involving 80 liver cirrhosis patients with esophageal variceal bleeding treated with octreotide. Data on demographics, Child-Pugh class, constituent clinical/laboratory parameters, transfusion types, co-medications, and bleeding duration were recorded. Data non-normality was established, and Spearman's rank correlation test (Spearman's rho) was applied to evaluate the correlation between Child-Pugh score and bleeding duration. Patients were predominantly aged 40–60 years (58.8%) and male (72.5%). Most patients belonged to Child-Pugh Class B (56.3%), followed by Class A (23.8%) and Class C (20.0%). Packed Red Cells (PRC) were the most frequently transfused blood component (73.8%, mean 3.59 units). The overall mean bleeding duration was 2.93 ± 1.92 days, with Class A averaging 2.53 ± 2.04 days, Class B 2.76 ± 1.43 days, and Class C 3.88 ± 2.68 days. Spearman's correlation analysis revealed a statistically significant positive correlation between Child-Pugh score and bleeding duration (r = 0.252, p = 0.024). There is a statistically significant positive correlation between Child-Pugh score and bleeding duration in liver cirrhosis patients receiving octreotide therapy. Higher Child-Pugh scores are associated with prolonged duration of bleeding.

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Journal Info

Abbrev

VitaMedica

Publisher

Subject

Health Professions Public Health

Description

Jurnal ini adalah Jurnal Asclepius : Jurnal Rumpun Kesehatan Umum yang bersifat peer-review dan terbuka. Bidang kajian dalam jurnal ini termasuk riset Ilmu Kesehatan ...