<![CDATA[Stroke is a non-communicable disease that remains a leading cause of death and disability worldwide. The risk of stroke is influenced by several modifiable factors, including a history of comorbidities, stress levels, and physical activity. This study aimed to analyze the relationship between a history of comorbidities, stress levels, and physical activity with the incidence of stroke among patients at RSU Royal Prima Medan in 2026. A quantitative method with a cross-sectional design was employed. The sample comprised all 53 stroke patients treated between January and April 2026, selected through total sampling. Data were collected using questionnaires and analyzed univariately and bivariately using the Chi-Square test at α = 0.05. Results showed that the majority of respondents were over 56 years old (67.9%), male (54.7%), and had ischemic stroke (52.8%). Bivariate analysis revealed p-values of 0.509 for comorbidities, 0.027 for stress levels, and 0.402 for physical activity. Stress levels were significantly associated with stroke incidence, whereas comorbidities and physical activity were not. Efforts to control chronic diseases, manage stress, and adopt a healthy lifestyle remain essential to reduce stroke risk.]]>
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