Acne is one of the most common skin conditions affecting adolescents. It is a dermatological disorder caused by excessive sebum accumulation that blocks skin pores, leading to bacterial growth and inflammation. One of the most common approaches to managing acne is self-medication, defined as the selection and use of medicines without a physician’s prescription to treat self-recognized health conditions. This study aimed to determine the correlation between the level of knowledge and attitudes toward self-medication for acne among students of State Senior High School 1 of Sendang Agung. This study employed a quantitative research design using a cross-sectional approach. The samples were selected through a simple random sampling technique, resulting in a total of 82 respondents. Data were collected using a questionnaire that had been tested for validity and reliability. The findings showed that the respondents' level of knowledge was categorized as high (17.1%), moderate (56.1%), and low (26.8%). Meanwhile, attitudes toward acne self-medication were classified as good (9.8%), fair (84.1%), and poor (6.1%). Statistical analysis revealed a significant correlation between the level of knowledge and attitudes toward self-medication for acne among students of State Senior High School 1 of Sendang Agung, with a p-value of 0.023. In conclusion, most students demonstrated a moderate level of knowledge and fair attitudes toward acne self-medication. The findings indicate a statistically significant correlation between the level of knowledge and attitudes toward self-medication for acne among students of State Senior High School 1 of Sendang Agung.
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