Catfish is one of the fishery commodities that has important economic value in the aquaculture industry. However, the success of cultivation is often constrained by bacterial disease attacks that cause decreased productivity, high mortality, and economic losses. One of the main diseases that affect catfish is Enteric Septicemia of Catfish (ESC) and Motile Aeromonads Septicemia (MAS). This activity aims to evaluate the resistance of catfish to the bacteria Edwardsiella ictaluri and Aeromonas hydrophila. The method used was an experiment with the test treatment of the bacteria Edwardsiella ictaluri and Aeromonas hydrophila on selected Siamese catfish and UPR Siamese catfish. Before the challenge test was carried out, an experiment was first carried out to determine the LD50 value in each bacteria. The parameters observed included clinical symptoms and mortality rates during maintenance. The observation data were tabulated using the Microsoft Excel 2017 program tool and analyzed descriptively. The results of the study showed that the LD50 value of catfish infected with Edwardsiella ictaluri bacteria.obtained at a concentration of 1.2x108 CFU/mL, while in Aeromonas hydrophila bacteria at a concentration of 1.8x109 CFU/mL, the selected Siamese catfish had better resistance to the bacterial pairing of Edwardsiella ictaluri and Aeromonas hydrophila than the Siam catfish UPR.
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