<![CDATA[This study aims to develop an e-module of reaction rate based on Learning Cycle 7E integrated with STEM (science, technology, engineering, and mathematics) to improve students' higher-order thinking skills in class XI-G of SMA Negeri 2 Percut Sei Tuan. This study uses the Research and Development (R&D) method with a 4D development model consisting of the define, design, development, and disseminate stages. The results of the study indicate that the developed e-module is feasible and meets the BSNP criteria with an average assessment of material expert validators of 88.83% and media experts of 89.03%. The effectiveness of the e-module in improving students' higher-order thinking skills is shown through the results of the hypothesis test, where the t-count (2.89) is greater than the t-table (1.70), and the N-Gain result is 0.77 (high category). Furthermore, student responses to the reaction rate e-module based on the 7E Learning Cycle integrated with STEM were very positive, as evidenced by the average student response questionnaire score of 92.41%, which is categorized as very practical. Thus, the developed reaction rate e-module based on the 7E Learning Cycle integrated with STEM (science, technology, engineering, and mathematics) is declared valid, effective, and practical for improving students' higher-order thinking skills.]]>
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