<![CDATA[This research aims to determine the feasibility of an e-module developed using Instagram as a biology instructional media on the topic of immune system and to find out its potential of effectiveness to develop students' argumentation skills. This research was conducted based on Research and Development framework through Analysis, Design, and Development stages. The subjects of the study were two biology experts, two biology instructional media experts, a biology teacher, and 30 grade-11 students of a high school in Yogyakarta province. The research data include the value judgements of the e-module feasibility which were collected using expert judgement sheets for biology experts, instructional media experts, and biology teachers, while data of students' argumentation skill obtained by pretest and posttest. All data were analyzed descriptively. The findings show that based on the feasibility judgements by 92% of biology experts reviews, 81.5% media experts reviews, and 77.5% of teacher review towards the feasibility criteria it is noted that the developed e-module is feasible to be used in biology instruction. Thus, the e-module is noticeably effective in fostering students’ argumentation skills based on the gain score obtained by 0.54 which means reached to medium category of students’ argumentation skill achievement.]]>
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