<![CDATA[This study aims to determine differences in higher order thinking skills and science process skills of students learn who use guided inquiry learning with Flow Diagram strategy and guided inquiry learning. The research design uses quasi-experimental with Pretest-Posttest Control Group Design. The population in this study were students of class X MIA SMA Negeri 1 Kalitidu the academic year 2015/2016. The sample used in this research is class X MIA 4 as an experimental class and class X MIA 2 as the control class with a total of 2 class of 64 students. Instruments used include high-level thinking skills tests and observation sheets science process skills of students. Data analysis technique used is the multivariate analysis (MANOVA) at the 5% significance level with SPSS 17.0 for Windows. Based on the analysis obtained the following results. (1) There is the influence of higher-order thinking skills to learn to use guided inquiry learning with Flow Diagram strategy (0.000 <0.05); (2) There is the influence of science process skills that students learn to use guided inquiry learning strategy with Flow Diagram strategy (0.000 <0.05).]]>
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