Journal Pharmasci (Journal of Pharmacy and Science)
Vol. 10 No. 2 (2025): Journal Pharmasci (Journal of Pharmacy and Science)

The Effect of HPMC (Hydroxypropyl Methylcellulose) on the Physical Stability of Peel-Off Gel Masks Containing Aloe Vera (Aloe vera) and Moringa Leaves (Moringa oleifera L.): Pengaruh HPMC (Hydroxy Propyl Methyl Cellulose) Terhadap Stabilitas Fisik Masker Gel Peel-Off Ekstrak Lidah Buaya (Aloe vera) dan Daun Kelor (Moringa oleifera L.)

Soraya Isvandaria Devie (Akademi Farmasi Surabaya)
Fitria Abbas Thalib (Akademi Farmasi Surabaya)
Silvi Ayu Wulansari (Akademi Farmasi Surabaya)



Article Info

Publish Date
08 Jul 2025

Abstract

P Researchers prepared the peel-off gel mask formulation, which combines Aloe vera and moringa leaf extract (Moringa oleifera L.), in three different formulas with varying concentrations of HPMC. Stability testing was conducted using the freeze-thaw method for six cycles at temperatures of 4? and 40?. Physical stability parameters evaluated included organoleptic properties, homogeneity, pH, spreadability, and drying time. Organoleptic observations revealed color differences among the three formulas: Fm1 and Fm2 appeared dark green, while Fm3 exhibited a moss green color. No differences were observed before and after the freeze-thaw test in terms of color; however, consistency changed, becoming slightly more liquid from cycle 2 through cycle 6. Homogeneity testing showed phase separation in formulas Fm1 and Fm2 during the second cycle and in Fm3 during the fourth cycle. There were no significant differences in pH, spreadability, or drying time after undergoing the freeze-thaw stability test.

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Journal Info

Abbrev

jps

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

Description

Journal of Pharmacy and Science (Pharmasci) publishes full-length original articles and reviews. The scope of the journal is pharmaceutical and basic science, including its research and application. The editors, therefore, welcome contributions on the following topics: 1. Clinical pharmacy 2. ...