Article Per Year (5 Year)
p-Index From 2020 - 2025
2.554
P-Index
This Author published in this journals
All Journal Jurnal Kimia Riset Jurnal Surya Medika Biota Jurnal Abdi Insani SIMBIOSA Humanism : Jurnal Pengabdian Masyarakat Journal Pharmasci (Journal of Pharmacy and Science) Journal of Experimental and Clinical Pharmacy (JECP) NUSANTARA: Jurnal Pengabdian Kepada Masyarakat Jurnal Masyarakat Madani Indonesia Jurnal Komunitas Farmasi Nasional
Wulansari, Silvi ayu
Akademi Farmasi Surabaya
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

Published : 16 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 16 Documents
Search

 1   2 
Pengaruh Variasi Kombinasi Konsentrasi Surfaktan Non Ionik (Span 60 Dan Peg-40 Hco) Terhadap Stabilitas Fisik Mikroemulsi Koenzym Q10 Silvi Ayu Wulansari; Umarudin Umarudin
Jurnal Surya Medika (JSM) Vol 6 No 1 (2020): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v6i1.1534

Abstract

Coenzyme Q10 is a compound that functions as an antioxidant with a large molecular weight of 863.36 g / mol and has lipophilic properties. This makes coenzyme Q10 need to be formulated to improve the solubility of the material and the delivery system in the skin. This study aims to determine the effect of various combinations of non-ionic surfactant concentrations (span 60 and PEG-40 HCO) on the physical stability of microemulsions. In this study Coenzyme, Q10 was formulated in oil-type microemulsion preparations in water. The oil used as the oil phase is rice bran oil with a combination of surfactant span 60 and PEG-40 HCO and 96% ethanol as a cosurfactant. the microemulsion was made in 4 microemulsion formulas namely FI, F2, F3, and F4, each formula was made 3 replications. Microemulsion preparations were evaluated after 24 hours after the preparations were made, observations made included organoleptic (shape, color, and phase formed), pH, viscosity, droplet size, zeta potential, and polydispersity index before and after centrifugation test with 10,000 rpm for 30 minutes. The research data were processed statistically using the Kruskal-Wallis analysis and Mann-Whitney follow-up tests. The results showed that the surfactant concentration affected physical characteristics (viscosity, droplet size, zeta potential, and polydispersity index) with a significantly different result (p <0.05) but the surfactant concentration did not affect the pH with the results not significantly different (p> 0, 05).
PENGARUH KONSENTRASI SURFAKTAN TERHADAP KARAKTERISTIK FISIK NANOEMULSI DAN NANOEMULSI GEL KOENZYM Q10 Silvi ayu Wulansari; Ririn Sumiyani; Ni Luh Dewi Aryani
Jurnal Kimia Riset Vol. 4 No. 2 (2019): Desember
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v4i2.16164

Abstract

Coenzyme Q10 is a compound that functions as an antioxidant with a large molecular weight of 863.36 g/mol and has lipophilic properties. This makes coenzyme Q10 need to be formulated to improve the solubility of the material and the delivery system in the skin. This study aims to determine the effect of surfactant variations (a combination of PEG-40 HCO and Span 80) on the physical characteristics of nanoemulsion and nanoemulsion gel preparations. Coenzyme Q10 is formulated using the rice bran oil oil phase with the combination surfactant. This research was made in 3 nanoemulsion formulas  FI, F2, F3 and 3 nanoemulsion gel formulas  F4, F5, F6. Evaluation of physical characteristics is done after 24 hours after the preparation is complete, observations made include organoleptic (shape, color and phase formed), pH, viscosity, droplet size, zeta potential and polydispersity index. The research data were processed statistically using the Kruskal-Wallis analysis and Mann-Whitney follow-up tests. The results showed that the surfactant concentration affected physical characteristics (viscosity, droplet size, zeta potential and polydispersity index) with a significantly different result (p <0.05) but the surfactant concentration did not affect the pH with the results not significantly different (p> 0.05)
VALIDASI METODE ANALISA PADA PENETAPAN KADAR KOENZIM Q10 DALAM SEDIAAN MIKROEMULSI MENGGUNAKAN METODE SPEKTROPHOTOMETER UV-VIS Silvi ayu Wulansari; Eziah Ika Lubada
Jurnal Kimia Riset Vol. 5 No. 1 (2020): Juni
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v5i1.19241

Abstract

Koenzim Q10 banyak digunakan dalam bidang kosmetika karena dapat digunakan sebagai antioksidan, namun koenzim Q10 memiliki kekurangan yaitu hanya dapat larut dalam minyak dan memiliki ukuran partikel yang besar sehingga sulit untuk masuk pada kulit. Koenzim Q10 diformulasikan dalam sediaan mikroemulsi untuk memperbaiki penetrasi dalam kulit. Untuk menunjang efek terapetik dari sediaan mikroemulsi perlu dikembangkan penetapan kadar Koenzim Q10 menggunakan spektrofotometer Uv-Vis, menggunakan pelarut [Acetonitril : 2-propanol (84:16)] dan diukur pada panjang gelombag 275 nm. Hasil penelitian menunjukkan bahwa koenzim Q10 linier pada rentang konsentrasi 25,5 – 153,0 ppmdengan LOD dan LOQ sebesar 5,25 µg/ml dan 17,48 µg/m. Metode peetapan kadar koenzim Q10 pada sampel mikroemulsi memiliki nilai akurasi dan presisi yang cukup baik dengan rata-rata perolehan kembali 100,70% dan SD 0,41% . Spektrofotometer UV-Vis dapat digunakan sebagai metode dalam penetapan kadar koenzim Q10 dalam sediaan mikroemulsi yang memenuhi persyaratan validasi penetapan kadar sediaan farmasi.
Aplikasi Hand Sanitizer Kitosan Cangkang Bekicot Sebagai Antibakteri dan Upaya Preventif Covid 19 Umarudin Umarudin; Surahmaida Surahmaida; Syukrianto Syukrianto; Silvi Ayu Wulansari; Siti Nurhaliza
SIMBIOSA Vol 9, No 2 (2020): JURNAL SIMBIOSA
Publisher : Universitas Riau Kepulauan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33373/sim-bio.v9i2.2669

Abstract

Salah satu infeksi akibat bakteri yang dapat menyebabkan saluran pernapasan  adalah Klebsiella pneumonia. Desain yang digunnakan pada penelitian ini adalah true eksperimental. Tahapan penelitian dengan isolasi kitosan cangkang bekicot yaitu deproteinasi, demineralisasi, depigmentasi, dan deasetilasi, pembuatan hand sanitizer kitosan cangkang bekicot. Analisa data yang digunakan deskriptif kualitatif dan kuantatif untuk uji evaluasi organoleptis dan jumlah koloni bakteri dan uji ANOVA satu arah jika terdapat perbedaan dilakukan uji lanjut dengan uji LSD. Hasil penelitian menunjukan bahwa uji organoleptis hand sanitizer selama 28 hari dan didapatkan hasil sesuai spesifikasi yaitu berbentuk gel, warna transparan dan tidak ada aroma yang dikeluarkan, pH sediaan hand sanitizer sesuai dengan standart pH kulit, sediaan hand sanitizer kitosan cangkang bekicot homogen, jumlah koloni formula 2 (6%) dengan rata-rata 0,67 koloni, 3% dengan rata-rata 2,67 koloni lebih efektife alam menghambat pertumbuhan bakteri jika dibandingkan dengan K (-) dengan rata-rata 107,67. Perlakuan hand sanitizer 3% berbeda nyata secara signifikan dengan kontrol dan 6%, perlakuan hand sanitizer 6% berbeda nyata signifikan dengan kontrol dan 3%. Semakin tinggi konsentrasi cangkang bekicot semakin besar kemampuan daya hambat dan bersifat bakterisidal.
Antioxidant Activity Test of Ubiquinone Microemulsion with DPPH (1,1-Diphenyl-2-picrylhydrazyl) Method : Uji Aktivitas Antioksidan Mikroemulsi Ubiquinone dengan Metode DPPH (1,1-Difenil-2-pikrilhidrazil) Silvi Ayu Wulansari; Umarudin; Floreta Fiska Yuliarni
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 7 No. 2 (2022): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v7i2.286

Abstract

Ubiquinone is an antioxidant formulated in cosmetic preparations. It is necessary to test the atioxidant activity to ensure the quality of the preparation. The purpose of this study was to determine the antioxidant activity of the ubiquinone formulated in microemulsion preparations. The Ubiquinone were formulated into mikroemultion with cocentrations 0.25%, 0.5%, 0.75% and 1%, separately. The DPPH method was selected as the atioxidant activity test.. The data analysis in this study was descriptive to determine the IC50 value of ubiquinone microemulsion preparations F1, F2, F3 and F4 and ubiquinone as a comparison. The result shows that the antioxidant value of IC50 ubiquinone microemulsion of F1, F2, F3, and F4 are 56.48 ppm, 49.92 ppm, 32.76 ppm, and 20.71 ppm, respectively. The average value of ubiquinone microemulsion is 59.16 ppm. This research concludes that the microemulsion formula F1-F4 of ubiquinon has a very strong antioxidant activity compared to ubiquinone.
Penyuluhan Pemanfaatan Ekstrak Daun Mimba sebagai Sabun Kertas Antiseptik Silvi Ayu Wulansari; Lailatus Sa’diyah; Umarudin Umarudin
Humanism : Jurnal Pengabdian Masyarakat Vol 3, No 3 (2022): Desember
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/hm.v3i3.14595

Abstract

COVID-19 (Corona Virus Diseases-19) yang ditetapkan oleh World Health Organization (WHO) sebagai pandemi di level dunia mulai tahun 2020.  Provinsi Jawa Timur memiliki jumlah kasus positif Covid-19 nomor urut dua setelah DKI Jakarta. Berbagai  upaya telah dilakukan pemerintah untuk menekan angka kasus Covid-19 dengan cara menjaga prokes seperti mencuci tangan dengan sabun. Sabun perperan penting dalam pencegahan dan penurunan angka penyebaran Covid-19, upaya penyebaran tersebut perlu adanya solusi pemanfaatan daun nimba sebagai zat aktif pada sabun. Daun mimba terdapat senyawa yang bersifat antibakteri dan antivirus, sehingga daun mimba dapat dijadikan sebagai senyawa bioaktif pada sabun kertas dengan dilakukan penyuluhan program pengabdian mengenai pemanfaatan herbal untuk pencegah penyebaran Covid-19. Program pengabdian masyarakat ini mendukung Sustainable Development Goals (SDGs). Sasaran kegiatan pengabdian ini pada siswa SMK Farmasi Kapasari Surabaya. Kegiatan ini dilakukan secara luring dengan metode penyuluhan. Target dari kegiatan pengabdian kepada siswa untuk meningkatkan kepedulian terhadap kesadaran mengenai bahan alam yang diolah untuk dapat menghasilkan suatu produk yang bermanfaat dalam ikut serta mencegah penyebaran Covid-19. Berdasarkan hasil yang didapatkan dari sepuluh aspek penilaian pada pre-test, terdapat kenaikan pada setiap aspek setelah di lakukan penyuluhan. Hal ini menunjukkan siswa dari Sekolah Menegah Farmasi lebih memahami pemanfaatan bahan alam sebagai sabun kertas untuk mencegah penyebaran Covid-19.
Comparison and Evaluation of Fermentation Results of Probiotic Products by Acenobacter xylinum: Komparasi dan Evaluasi Hasil Fermentasi Produk Probiotik dengan Kultur Acenobacter xylinum Kinanti Lestari; Floreta Fiska Yuliarni; Lailatus Sa’diyah; Silvi Ayu Wulansari; Selvyronica Eka Agustine; Fatma Ariska Trisnawati; Silfiana Nisa Permatasari
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 8 No. 1 (2023): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v8i1.334

Abstract

products with Acetobacter xylinum starter included Nata and Kombucha. The large number of studies on probiotic product innovation should be followed by a survey on public acceptance of the products. This research aim to compare of the yield of probiotic products after fermentation process which was evaluated from a physical perspective, pH and public acceptance. This research is an experimental study to compared the fermented results of two types of probiotic products, nata and kombucha which are differentiated based on their raw ingredients. The nata products sample which had the largest thickness and weight of cellulose biofilm was NDC, while the kombucha products sample which had the largest thickness and weight of cellulose biofilm was KGF. pH of all samples, both nata and kombucha, decreased during the fermentation process. The samples of nata products that were most accepted by the panelists were NDC and NDM in terms of color, smell and taste. The samples of kombucha products that were most accepted by the panelists were KAF and KMF in terms of color, smell and taste.
Pelatihan Pengolahan Minyak Jelantah Sebagai Dasar Pembuatan Lilin Warna-Warni Di Kelompok Ibu PKK Karang Menjangan Devianti, Vika Ayu; Sa'diyah, Lailatus; Silvi Ayu Wulansari
Nusantara: Jurnal Pengabdian kepada Masyarakat Vol. 4 No. 1 (2024): Februari : Jurnal Pengabdian Kepada Masyarakat
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/nusantara.v4i1.1849

Abstract

The community service carried out by the Surabaya Pharmacy Academy team aims to increase public awareness about the dangers of used cooking oil regarding the potential diseases that can occur if consumed continuously. The waste cooking oil produced is processed into colorful candle products. The colorful candles produced can be used as lighting at home or can also be used as room decoration because of their attractive colors and shapes. Based on the results of this community service, the community was very enthusiastic and gave a positive response to this training. The community has new insight into processing used cooking oil waste into colorful candles. People can practice making colorful candles again at home. This product can also be a creative and innovative business idea.
Pengaruh Variasi Jenis dan Konsentrasi Gelling Agent Terhadap Karakteristik Fisik Emulgel Koenzim Q10 Wulansari, Silvi Ayu; Umarudin, Umarudin; Sa’diyah, Lailatus
Journal of Experimental and Clinical Pharmacy (JECP) Vol 2, No 2 (2022): August 2022
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v2i2.464

Abstract

Koenzim Q10 berperan sebagai antioksidan untuk mencegah penuaan akibat radikal bebas. Koenzim Q10 untuk memenuhi kebutuhan sel jumlahnya terbatas, sehingga untuk mencegah timbulnya penuaan dengan menggunakan skin care secara topical, salah satu bentuk sediaan topikal yaitu emulgel. Penggunaan bahan pembentuk gel merupakan komponen penting dalam sediaan gel, karena jenis dan konsentrasi bahan pembentuk gel dapat mempengaruhi karakteristik fisik gel. Penelitian ini bertujuan untuk mengetahui pengaruh variasi jenis dan konsentrasi gelling agent terhadap sifat fisik emugel koenzim Q10. Pada penelitian ini dibuat 6 formula dengan variasi jenis dan konsentrasi gelling agent. F1, F2, F3 mengandung carbopol 940 (0,5; 0,75 dan 1%) F4, F5, F6 mengandung CMC-Na (3; 3,5 dan 4%) dan semua formula emugel mengandung koenzim Q10 0,5%. Parameter yang diamati adalah karakteristik fisik emulgel koenzim Q10 (pengamatan organoleptis dan homogenitas, pengujian pH, daya sebar, pengujian viskositas, dan pengujian daya lekat). Analisa data penelitian ini dengan One Way Anova. Hasil penelitian karakteristik fisik sediaan pada formula 1-6 emulgel koenzim Q10 dari segi organoleptis memiliki karateristik sesuai dengan spesifikasi dari bentuk sediaan, warna, aroma dan homogenitas. Temuan penelitian ini sediaan emulgel yang mengandung carbopol 940 pada F1, F2, F3 memiliki nilai pH (5,91c; 5,77b; 5,32a) daya sebar (6,4c; 6,1b; 5,8a) viskositas (2.445a; 2.976b; 3.083c) dan daya lekat (18a; 21b; 29c) dan sediaan emulgel yang mengandung CMC-Na pada F4, F5, F6  memiliki nilai pH (6,25a ; 6,28a; 6,27a) daya sebar (6,6c; 6,3b; 5,1a) viskositas (2.379a; 2.926b; 3.157c) dan daya lekat (13a; 19b; 37c). Simpulan penelitian ini gelling agent yang digunakan pada emulgel koenzim Q10 dapat berpengaruh terhadap karakteristis fisik sediaan, dari keenam formula (F1-F6) formula F2 yang menggunakan gelling agent carbopol 940 merupakan formula yang paling optimum.Coenzyme Q10 acts as an antioxidant to prevent aging caused by free radicals. Coenzyme Q10 to meet the needs of cells is limited in number, so to prevent aging by using skin care topically, one of the topical dosage forms is emulgel. The use of gelling agents is an important component in gel preparations, because the type and concentration of gelling agents can affect the physical characteristics of the gel. This study aims to determine the effect of variations in the type and concentration of gelling agent on the physical properties of emugel coenzyme Q10. In this study, 6 formulas were made with variations in the type and concentration of gelling agent . F1, F2, F3 contained carbopol 940 (0.5 ; 0.75 and 1%) F4, F5, F6 contained CMC-Na (3; 3.5 and 4%) and all emugel formulas contained coenzyme Q10 0.5% . Parameters observed were physical characteristics of coenzyme Q10 emulgel (organoleptic and homogeneity observations, pH testing, dispersion, viscosity testing, and adhesion testing). Analysis of this research data with One Way Anova . The results of the research on the physical characteristics of the dosage form 1-6 emulgel coenzyme Q10 in terms of organoleptic have characteristics in accordance with the specifications of the dosage form, color, aroma and homogeneity. The findings of this study were that the emulgel preparation containing carbopol 940 at F1, F2, F3 had a pH value (5.91 c ; 5.77 b ; 5.32 a ) dispersion (6.4 c ; 6.1 b ; 5.8 ). a ) viscosity (2,445 a ; 2,976 b ; 3,083 c ) and adhesion (18 a ; 21 b ; 29 c ) and emulgel preparations containing CMC-Na at F4, F5, F6 had a pH value (6.25 a ; 6 ,28 a ; 6.27 a ) dispersibility ( 6.6 c ; 6.3 b ; 5.1 a ) viscosity ( 2,379 a ; 2,926 b ; 3,157 c ) and adhesion (13 a ; 19 b ; 37 c ). The conclusion of this research is that the gelling agent used in emulgel coenzyme Q10 can affect the physical characteristics of the preparation, of the six formulas (F1-F6) formula F2 using the gelling agent carbopol 940 is the most optimum formula.
Antibacterial Potention and pH Analysis of Kombucha with Anna Apple (Malus domestica) Peel as Its Substrate Lestari, Kinanti Ayu Puji; Wulansari, Silvi Ayu
Biota Vol 15 No 1 (2022)
Publisher : Universitas Islam Negeri Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20414/jb.v15i1.363

Abstract

This study aimed to determine the antibacterial abilities of Kombucha with Anna apple peel as the substrate. This study was conducted on the antibacterial assay of Kombucha with the formulation of 10g (formulation A), 15g (formulation B), and 20g (formulation C) apple peels. Each formulation then made three different test concentrations of an antibacterial test by the Kirby Bauer method. There was a decrease in the pH value measured before and after fermentation of kombucha apple peel due to the production of acetic acid formed from metabolic activity between bacteria and yeast as a culture of kombucha beverage. The results of the antibacterial test showed that all of the test concentrations could inhibit the growth of the test bacteria until they were in the category of medium and high inhibition. The largest diameter of the inhibition zone was shown by formula C with a concentration of 100% (17 mm). The diameter of the inhibition zone is directly proportional to the amount of apple peel contained in the formula and the concentration of the sample being tested.
Co-Authors Anidnya, Widya Dara Aryani, Ni Luh Dewi Bawanda, Edward Melfin Devianti, Vika Ayu Evy Aryanti Eziah Ika Lubada Fatma Ariska Trisnawati Galuh Gondo Kusumo Kinanti Lestari Lailatus Sa’diyah Lestari, Kinanti Ayu Puji Ramadhan Renaisansa Ririn Sumiyani Romadhona, Eliza Stepani Sa'diyah, Lailatus Sa’diyah, Lailatus Sa’diyah, Lailatus Selvyronica Eka Agustine Silfiana Nisa Permatasari Siti Nurhaliza Surahmaida Surahmaida Syukrianto Syukrianto Syukrianto Syukrianto, Syukrianto Umarudin Umarudin Umarudin Umarudin Umarudin Umarudin, Umarudin Vika Ayu Devianti Widya Dara Anindya Yuliarni, Floreta Fiska