Adolescents are vulnerable to e-cigarette use, yet eighth-grade students at SMP Kerinci have never received structured education on its dangers. To analyze and compare the effectiveness of TikTok-based video and poster health education on knowledge and attitudes regarding e-cigarette dangers. This quantitative quasi-experimental study with a two-group pretest-posttest design was conducted in August 2026 at MTsN 2 Kerinci. Sixty-four eighth-grade students were purposively sampled and divided into TikTok and poster groups (n=32 each). Data were collected using questionnaires and analyzed using Wilcoxon, paired t, Mann-Whitney U, and independent t tests (α=0.05). Mean knowledge scores increased from 5.53 to 8.59 in the TikTok group and from 5.38 to 6.94 in the poster group; mean attitude scores rose from 32.25 to 41.12 and from 31.50 to 37.00, respectively (all p<0.001). Knowledge and attitude gains were greater in the TikTok group than in the poster group (p<0.001). Both media effectively improved students' knowledge and attitudes about e-cigarette dangers, but TikTok-based videos were more effective and are recommended as an educational medium in the School Health Program (UKS).
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