Integration of STEM (Science, Technology, Engineering, and Mathematics) in learning combines multiple scientific disciplines to create meaningful and integrated learning experiences. This study aimed to determine the effect of the STEM approach on students’ cognitive learning outcomes and creative attitudes in learning the excretory system at SMAN 1 Sirenja. The research employed a quasi-experimental design involving all students of class XI IPA as the research population. A total of 40 students participated in the study, consisting of 20 students in the experimental class (XI IPA 1) and 20 students in the control class (XI IPA 2). Samples were selected using a saturated sampling technique, in which all members of the population were included as research participants. The collected data were analyzed using SPSS version 22. The findings indicated that the STEM approach significantly improved students’ cognitive learning outcomes, with the experimental class obtaining a mean score of 75.10 compared to 50.45 in the control class. In addition, the STEM approach positively influenced students’ creative attitudes toward learning the excretory system. These findings suggest that STEM-based learning can serve as an effective instructional approach and may be considered by teachers as an alternative strategy to improve learning and creativity.
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