<![CDATA[Anxiety is an emotional mental health challenge that can disrupt psychological and physiological conditions, requiring holistic non-pharmacological interventions such as spiritual dhikr therapy. This study aims to systematically analyze the effectiveness of spiritual dhikr therapy interventions in reducing anxiety levels across various populations and to synthesize its implications for holistic nursing care. This study employs a descriptive literature review method by analyzing ten selected scientific articles published between 2023 and 2026, evaluating quasi-experimental studies, descriptive case studies, and qualitative research. The synthesis indicates that dhikr therapy consistently reduces anxiety scores (evaluated via HARS, ZSAS, AAS, and DAS scales) across diverse age groups, ranging from final-year students and preoperative patients to chronically ill patients and the elderly experiencing death anxiety. Conceptually, the rhythmic recitation of thayyibah sentences induces a religious relaxation response that helps stabilize autonomic nervous system activity. The study concludes that dhikr therapy is an effective non-pharmacological adjunctive intervention. Recommendations for standardizing dhikr therapy into nursing Standard Operating Procedures (SOPs) are proposed as developmental guidelines requiring further longitudinal clinical evaluation.]]>
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