<![CDATA[Background: Patients with urinary catheters are at risk of developing catheter-associated urinary tract infections (CAUTIs), which may require antibiotic therapy. Rational antibiotic use involves appropriate indications, dosage, route, and duration of administration while considering potential side effects. Irrational use of antibiotics can lead to antimicrobial resistance. Antibiotic rationality in hospitals can be evaluated using the Gyssens method. This study aims to assess the rationality of antibiotic use in inpatients with urinary catheters at HAMBA Regional Hospital. Methods: This descriptive observational study with a retrospective approach was conducted from July to September 2024 at HAMBA Regional Hospital. A total of 41 samples were selected using total sampling. Data were collected from medical records and urine culture results, then analyzed univariately for patient characteristics, types of antibiotics, and antibiotic rationality using the Gyssens flowchart. Results: A total of 70.7% of antibiotic use in CAUTI patients was classified as rational. Irrational use (29.3%) was categorized into VI (incomplete data), V (no indication), IVa (more effective alternative antibiotics), and IVc (cheaper alternative antibiotics). Conclusion: The rationality of antibiotic use in inpatients with urinary catheters at RSUD HAMBA is generally good; however, there are cases where antibiotic selection can be optimized for cost-effectiveness and treatment safety.]]>
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