Journal of Pharmaceutical and Sciences.
Vol 4 No 1 (2021): JPS Volume 4 Nomor 1 (2021)

Aktivitas Antimikroba Jangjingki (Oxalis corniculata L.) Terhadap Pertumbuhan Bakteri Staphylococcus Aureus, Escherichia coli Dan Jamur Candida albicans

Misrahanum Misrahanum (Jurusan Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Syiah Kuala)
Syarifah Dhea Almunawwarah (Jurusan Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Syiah Kuala)
Hira Helwati (Jurusan Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Syiah Kuala)
Hilda Maysarah (Jurusan Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Syiah Kuala)
Sadli Sadli (Jurusan Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Syiah Kuala)



Article Info

Publish Date
26 Jun 2021

Abstract

Jangjingki (Oxalis corniculata L.) is a plant from Oxalidaceae that has potential as a natural antimicrobial agent. The purpose of this research is to see the antimicrobial activity of methanol extract of jangjingki against the growth of Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922, and Candida albicans ATCC 10231. The thick extract of jangjingki was obtained by the maceration method with methanol solvent. At the same time, the antimicrobial activity test on S. aureus and E. Coli bacteria was carried out using the hole diffusion method. The simplicia characterization showed 7.17% water, 9.68% of total ash, 11.67% water-soluble extract, and 9.17% of the ethanol-soluble section. At the same time, the methanol extract of jangjingki characterization showed 22.5% of water, 10.16% of total ash, 55.83% water-soluble extract, and 62.91% of the ethanol-soluble section. Phytochemical test results showed that the methanol extract of jangjingki contains alkaloids, saponins, flavonoids, tannins, and steroids. The results of the antimicrobial activity test with variations in the concentration of jangjingki methanol extract 15, 20, 30, and 40% on S. aureus and E. Coli bacteria showed growth inhibition activity of these two bacteria, the largest diameter of the inhibition zone was formed when the extract was given a concentration of 40% with a diameter of the area. Resistance of 8,07 mm and 11 mm, respectively. Meanwhile, the test results of inhibition of growth of the fungus C. Albicans by presenting variations in the concentration of jangjingki methanol extract of 5, 10, 15, and 20% could not inhibit the growth fungus C. Albicans.

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Journal Info

Abbrev

jps

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

Description

Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, ...