<![CDATA[Based on a Taylor Nelson Sofres (TNS) survey of 1,800 women aged 20–39 years in five Asian countries, it is known that the average signs of aging in Asian women begin to appear around the age of 25. Dry skin is one of the indicators of premature aging triggered by increased transepidermal water loss (TEWL). Guava leaves (Psidium guajavaL.) contain flavonoids and phenolic compounds which have potential as natural moisturizing active ingredients. This study aims to formulate guava leaf ethanol extract into a body lotion, determine the best formula for skin hydration activity, and evaluate its stability. Laboratory experimental research. The extract was obtained by maceration using 70% ethanol and formulated at a concentration of 6% with three propylene glycol:glycerin ratios, namely F1 (8:10), F2 (8:8), and F3 (10:8), compared with the base (F0) and positive control (K+). Evalua-tions included physical quality, hedonic test, irritation test, accelerated stability test (6-cycle cycling test), and skin hydration test on 30 respondents using a digital skin analyzer. Hydration data were analyzed using the Friedman and Wilcoxon tests. All formulas met the requirements for pH, viscosity, spreadability, and oil-in-water emulsion type, and did not cause irritation. F1 provided the highest moisture increase (19.14%), which was not significantly different from K+ (20.75%; p = 0.304), while F2 (15.27%) and F3 (13.82%) were lower. F2 and F3 were less homo-geneous during testing. Guava leaf ethanol extract has the potential to be used as a natural moisturizing active ingredient in body lotion, with F1 as the optimal formula.]]>
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