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All Journal Syntax Idea Proceeding of International Conference Health, Science And Technology (ICOHETECH) JURNAL FARMASI DAN KESEHATAN INDONESIA Jurnal Medika Nusantara Parapemikir Jurnal Ilmiah Farmasi

Tatiana Siska Wardani

Universitas Duta Bangsa Surakarta

Author-ID : 5831589

Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Nursing Physics Public Health

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Literature Review: Antioxidant Test of Basil Leaves (Ocimum Sanctum) Noka Riyani; Kusumaningtyas Siwi Artini; Tatiana Siska Wardani
Proceeding of International Conference on Science, Health, And Technology 2021: Proceeding of the 2nd International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Basil leaves is family of lamiaceace, which is known as daun kemangi (Indonesia). This plant is widely use as a herb. Indonesian also used basil leaves as a seasoning in their food. It has chemical compound such as flavonoid so it has an antioxidant effect. The aim of this reseach is to find out the antioxidant effect of the basil leaves, the chemical compound of basil leaves. The method by reviewing online articles at Pubmed, sciencedirect and Google Scholar. Cemichal compound wes identified in some reseach. It show different potential base on the extraction proses. The antioxidant effect was tested using the DPPH method for determination of IC50. By reviewing articles, we can conclude that basil leaves have an antioxidant effect.

Literature Review: The Potencial Effect of Dandang Gendis Leave (Clinacanthus nutans Lindau) Kusumaningtyas Siwi Artini; Weri Veranita; Tatiana Siska Wardani
Proceeding of International Conference on Science, Health, And Technology 2021: Proceeding of the 2nd International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Indonesian are used to use herb to medicate a disease. One of the medicinal plants used is Clinacnathus nutans (Burm.f.) Lindau. Clinacnathus nutans Lindau is a traditional plant, commonly known as dandang gendhis (Java – Indonesia), ki tajam (Sunda – Indonesia), belalai gajah (Malaysia), Sabah Snake Grass (Singapore), and phaya yo (Thailand). It belonging to the Acanthaceae family. This study aimed to find out the the effect of giving the extract of Clinacnathus nutans Lindau to subject. This research method was using literature review. The information about Clinacanthus nutans Lindau collected from an online database such as Pub Med, Scient direct and Google Scholar. The number of chemical compound were identified from leaves. It contain of alkaloid, flavonoid, polifenol, saponin and tanin Some of the potential effect shown such as antihypoglycemic, antioxidant and anticancer, and analgetic. In this study,we can conclude that in the future Clinacnathus nutans Lindau is valuable to use as herbal medicine with more investigation.

Increased Levels of Fermented Soy Milk Amino Acids And Effectivenes Helping Reduce Uric Acid Serum In Male White Rats Danang Raharjo; Veranita Weri; Wardani tatiana siska
Proceeding of International Conference on Science, Health, And Technology 2021: Proceeding of the 2nd International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Soybean is one of the most important foodstuffs for the people of Indonesia, which is consumed to meet the nutritional needs of protein. Soybeans are consumed by the public as a side dish and snack. Soy milk is a form of processed soybean. Previous research has shown that tempeh, which is a form of fermented soybean, can reduce purine levels in soybeans, and can increase nutritional value, especially amino acid content. The purpose of this study was to determine the increase in amino acid content of fermented soy milk with the help of Lactobacilus Kasei bacteria, and its effect in helping to reduce serum uric acid levels in the blood of male white rats. Fermented soy milk is made of 250 grams of soybeans and squeezed in 5 liters of water, then heated. Lactobacilus kasei is used as a battery for fermentation and 500 grams of palm sugar is used as a source of nutrition for bacteria. The test to reduce uric acid levels was carried out in vivo by giving male white rats drinking as much as 10 mL, 20 mL, 30 mL, 40 mL, 50 mL for 14 days, then taking the blood through the tail vein, then measuring the uric acid levels using the strip method. test with the GCU easy tooch tool. To increase uric acid levels in male white rats was done by induction with chicken's liver. The results of measuring the levels of amino acids in the fermentation of soy milk increased between 1-2% with the following levels: Lysine 4.7%, Histidine 2.3%, Arginine 4.9%, Asparkate 7.8%, Treonine 2.9%, Serine 2.9%, Glutamate 14.2% , Proline 3.8%, Glycine 3.7%, Alanine 2.8%, Cystine 1.6%, Valine 3.2%, Methionine 1.2%, Isoleucine 3.8%, Leucine 5.9%, Tyrosine 2.7% , Phenylalanine 3.3%. Testing of uric acid levels in the blood of male white rats after fermented soy milk with various volume series were as follows: 6.70 mg/dL ± 1.16; 5.88 mg/dL ± 0.81; 4.63 mg/dL ± 0.92; 4.18 mg/dL ± 0.71; 4.16 mg/dL ± 0.96. Based on the results of the study, it can be concluded that fermented soy milk with the help of lactobacillus kasei bacteria can increase amino acid levels ranging from 1-2%, and the provision of drinking fermented milk can help reduce blood uric acid levels in male white rats with blood uric acid levels by 4.16 mg/dL ± 0.96.

Antioxidant peel off mask formulation of tamarind seeds ethanol extract Putri Djatmiko Marchia Afifah; Veranita Weri; Wardani Siska Tatiana
Proceeding of International Conference on Science, Health, And Technology 2021: Proceeding of the 2nd International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

The human body does not have excess reserves of antioxidants, so if a lot of radicals are formed, the body needs exogenous antioxidants. In an effort to get healthy skin we also must not forget about antioxidants to protect our skin. The adequacy of antioxidants is a bulwark to prevent the harmful effects of free radicals that damage the skin. But there are concerns about the possible side effects that have not been known from synthetic antioxidants, causing natural antioxidants to become a much needed alternative, one of which comes from plants. One plant that has antioxidant properties is tamarind seeds. Tamarindus indica L seeds contain polyphenol compounds and high antioxidant potential. The methanol extract of tamarind seeds has a higher content of polyphenol compounds and antioxidant potential than the methanol extract of other parts of the Tamarindus indica plant. Based on antioxidant research, the ethanol extract of tamarind seeds has an IC50 value of 40.21 ± 4.07262. The purpose of this study was to formulate an antioxidant peel off mask from tamarind seed extract using ethanol solvent with the maceration method. Furthermore, the extract obtained was formulated into a peel off preparation using 3 formulas with 5%, 10%, and 15% concentrations, respectively. The preparation is then tested for the evaluation of organoleptic preparations, homogeneity, pH, viscosity and flow properties, dispersibility, drying time, stability test, and irritation test

Existence Test Of Escherichia Coli and Pseudomonas Aeruginosa Bacteria in Packaging Drinking Water in Cemani Village, Sukoharjo Regency Nuraini Putri Rahmawati; Wardani Siska Tatiana; Veranita Weri
Proceeding of International Conference on Science, Health, And Technology 2021: Proceeding of the 2nd International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Clean, potable fresh water is becoming scarce in cities, the river which is the source of it is polluted with various wastes ranging from organic waste, household waste, to industrial waste. The quality of drinking water also affects public health, especially bottled drinking water. One of the parameters for the quality requirements of bottled drinking water is the test for Escherechia coli and Pseudomonas aeruginosa bacteria. The purpose of this study was to identify the contamination of Escherechia coli and Pseudomonas aeruginosa bacteria in bottled drinking water samples, using the MPN (Most Probable Number) method. The research method uses descriptive research. The research population of bottled drinking water in stalls around the Duta Bangsa University Surakarta campus is as many as 7 samples. Collecting data by laboratory observation, data analysis with descriptive analysis. The results of the study were carried out from seven samples of bottled drinking water, all samples were not detected by the Escherechia coli and Pseudomonas aeruginosa bacteria. The conclusion of this study is that there are no Escherechia coli and Pseudomonas aeruginosa bacteria in bottled drinking water sold in stalls around the campus of Universitas Duta Bangsa Surakarta.

Literature Study of Three Plant Formulations with Anti-Candida Albicans Activity in Feminine Liquid Soap Preparations Tatiana Siska Wardani; Kusumaningtyas Siwi Artini; Ilham Latansa
Proceeding of International Conference on Science, Health, And Technology 2021: Proceeding of the 2nd International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Candida albicans is a fungus that causes vaginal discharge in women. Leucorrhoea is a discharge from the vagina with a relatively small frequency, odorless, and clear. In Indonesia, there are many plants that have medicinal properties that are used in traditional medicine and are believed to have antifungal activities.Feminine hygiene soap is a liquid cleansing preparation for femininity which is made from basic ingredients and is used to clean the feminine area without causing irritation to the skin.This study aims to provide information about plants that have anti-fungal activity and their formulation as a good female liquid soap preparation with their activity as an anti-candida albicans. The method in this research is by searching literature studies from various journals. The results showed that each female liquid soap preparation with plants as the active substance gave different inhibition diameters. The difference between the active substance and the additive in the formulation affects the resulting inhibition diameter. Based on the results of a literature review, basil,cabbage (Brassica oleracea var. capitata alba) and waru (Hibiscus tiliaceus), has activity as an antifungal against Candida albicans.

Tests for the antibacterial and anti-inflammatory potential of the Asem Tengger plant (Radicula armoracia Robinson) obtained from the ethnomedicine study in the Tengger tribe Yaya Sulthon Aziz; Rony Setianto; Tatiana Siska Wardani; Nurul Nurhayati; Belinda Arbitya Dewi
Proceeding of International Conference on Science, Health, And Technology 2021: Proceeding of the 2nd International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Purpose: Local wisdom, especially in the Tengger Bromo tribe, East Java makes a potential that must be developed sustainably. The Asem Tengger plant (Radicula armoracia Robinson) is a plant that has antibacterial and anti-inflammatory potential in the Tengger tribe. This plant has high ICF and UV values. This study aims to determine the types of plants that have been used by the Tengger Tribe have antibacterial and anti-inflammatory activities with the dilution method and in vitro cell membrane stability. Methodology: Samples were taken from the Tengger Bromo Probolinggo Tribe, extracted by maceration using 95% ethanol. Characterization includes non-specific parameters and specific parameters. Identification of chemical contents includes flavonoids, glycosides, saponins, alkaloids. Antimicrobial test by dilution method, each concentration was tested on Staphylococcus aureus ATCC 2592, Bacillus subtilis ATCC 6633, Pseudomonas aeruginosa ATCC 27853, Salmonella typhi ATCC 13311, and Candida albicans ATCC 10231. The anti-inflammatory activity test using ethanol extract from muscle flour was made up to a concentration of 250 ppm, 500 ppm, 1000 ppm, and 2000 ppm with the in vitro anti-inflammatory test with the human red blood cell (HRBC) method. Results: Based on the antimicrobial test, Asem Tengger has the potential to be antibacterial to Staphylococcus aureus ATCC 2592 in the water and n-hexane fractions with a value of 2.5% MBC. The anti-inflammatory test showed the results of membrane stability of 57.97% from a concentration of 2000 ppm which shows a number that has the potential to be a reference for potential medicinal plants. Value: The Asem Tengger plant used by the Tengger tribe has the potential as new antimicrobials and anti-inflammatory

Ethanol Extract Guava Leaves (Psidium Guajava) Give Antidiabetic Effect On Male Mice With Alloxan Induction Tiara Ajeng Listyani; Aisyah Rabitha Alisi; Tatiana Siska Wardani
Proceeding of International Conference on Science, Health, And Technology Proceeding of the 3rd International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Diabetes mellitus is a chronic condition caused by increasing glucose level in blood. Long term use of antidiabetic drugs can cause various unwanted side effects, which makes people with diabetes try to use natural materials to control blood glucose levels. The aim of this study was to determine the antidiabetic activity of ethanol extract guava leaves (Psidium guajava) on male mice with alloxan induction. Mice were induced intravenously by alloxan dose of 160 mg/kg bw. After 7 days, mice were diabetic (blood glucose levels > 175 mg/dL) and were divided into 5 groups: negative control group (only treated with CMC-Na) ,positive control group (glibenclamide 0.65 mg/kg bw) and the 3 other groups were given ethanol extract guava leaves (Psidium guajava) at doses of 150 ,300 and 600 mg/kg bw. Dosage administered for 15 days and blood glucose levels was checked every 3 days using a glucotest. Data were analyzed by LSD (Least Significant Difference). Ethanol extract guava leaves (Psidium guajava) at doses of 150 ,300 and 600 mg/kg bw can lower blood sugar levels from day 3 to day 15 and was significantly different compared to the negative control group (p<0,05). Ethanol extract guava leaves (Psidium guajava) at doses of 150 ,300 and 600 mg/kg bw showed antidiabetic activity on male mice with alloxan induction.

TINGKAT KEPUASAN PASIEN TERHADAP PELAYANAN KOMUNIKASI, INFORMASI, DAN EDUKASI (KIE) OBAT OLEH TENAGA KEFARMASIAN DI APOTEK NOGOSARI FARMA Novalisa Nindhi Soraya; Era Wandira; Nadia Aisy Andika; Nasya Bella Salsabilla; Aris Prio Agus Santoso; Tatiana Siska Wardani
JURNAL FARMASI DAN KESEHATAN INDONESIA Vol. 2 No. 1 (2022): Jurnal Farmasi dan Kesehatan Indonesia
Publisher : Universitas Kristen Immanuel

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61179/jfki.v2i1.270

Telah dilakukan penelitian tentang tingkat kepuasan pasien terhadap pelayanan komunikasi, informasi, dan edukasi (KIE) obat oleh tenaga kefarmasian di apotek nogosari farma.Penelitian dilakukan dengan metode deskriptif dengan model penelitian observasi. Data dikumpulkan dari 50 responden melalui kuesioner pada bulan November 2021. Metode pengambilan sampel yang digunakan yaitu random sampling. Hasil penelitian menunjukkan bahwa dari 50 responden masih ada kekurangan dari tenaga teknis kefarmasian apotek dalam melakukan pelayanan KIE sesuai standart. Adapun hasil rata- rata presentase kepuasan pasien yakni 82% puas dan 12% pasien tidak puas.

Uji Aktivitas Anti Bakteri Ekstrak Etanol Dan Fraksi n-Heksana, Etil Asetat, Air Dari Kulit Buah Kakao (Theobroma cacao L.) Terhadap Bakteri Staphylococcus epidermidis ATCC 12228 Dengan Metode Difusi Dan Dilusi Regita Fortunata; Tatiana Siska Wardani; Desy Ayu Irma Permatasari
Jurnal Medika Nusantara Vol. 1 No. 4 (2023): November : Jurnal Medika Nusantara,
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/medika.v1i4.610

Cacao fruit peel (Theobroma cacao L.) is a plant that can be used as an antibacterial. Cocoa pod shell contains chemical alkaloids, flavonoids, tannins, saponins, triterpenoids. The purpose of this study was to determine the antibacterial activity of the ethanol extract, n-hexane fraction, ethyl acetate fraction, and water fraction from cocoa pod shells to determine the Minimum Inhibitory Concentration (MIC and Minimum Killing Concentration) of the most active fraction of cocoa pod shell on the growth of staphylococcus bacteria. epidermidis ATCC 12228. Cocoa pod powder was macerated using 96% ethanol, then fractionated using n-hexane, ethyl acetate, and water and tested for antibacterial activity using the diffusion and dilution method.Diffusion and dilution methods used the same concentration of 50% preliminary test 25%; 12.5%; 6.25%; 3.125%; 1.565% against Staphylococcus epidermidis ATCC 12228. The results of the antibacterial activity test using the diffusion method showed that the n-hexane fraction, ethyl acetate fraction, and water fraction from cocoa pod shell Each concentration of 50% inhibited the growth of bacteria in the presence of inhibition.The ethanol extract of cocoa pod shells had the greatest inhibition, namely 13.9 mm. The average diameter of the inhibition zone at a concentration of 25%; 12.5%; 6.25%; 3.125%; 1.565% respectively is 13.43 mm; 6.2mm; 4.23mm; 4.06mm; 3.46mm. The results of the dilution method test showed the MIC and KBM values of the ethanol extract, namely 12.5%, based on the results of the study it can be concluded that the ethanol extract has the most active antibacterial content.

Co-Authors Aisyah Rabitha Alisi Aprilia Rika Alvita Aris Prio Agus Santoso Bangkit Riska Permata Belinda Arbitya Dewi Desy Ayu Irma Permatasari Era Wandira Galuh Puspita Sari Ilham Latansa Kusumaningtyas Siwi Artini Listyani, Tiara Ajeng Musniati Musniati Nadia Aisy Andika Nasya Bella Salsabilla Noka Riyani Novalisa Nindhi Soraya Nuraini Putri Rahmawati Nurul Nurhayati Putri Djatmiko Marchia Afifah Putri Martani Nur Afifah Regita Fortunata Setianto, Rony Veranita Weri Veranita, Weri Yaya Sulthon Aziz

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