PENGARUH PEMBERIAN INFORMASI OBAT TERHADAP KEPATUHAN PENGGUNAAN OAT PADA PASIEN TB PARU DI RUMAH SAKIT TK III IM 07.01 LHOKSEUMAWE

Anggun Syafitri (Institut Kesehatan Deli Husada)
Viktor Edyward Marbun (Institut Kesehatan Deli Husada)
Hazimah Fitriyah Mardatilah (Institut Kesehatan Deli Husada)
Mezz Nazly Siti Rofieqoh (Institut Kesehatan Deli Husada)

Jurnal Penelitian Farmasi dan Herbal
Vol. 9 No. 1 (2026): Jurnal Penelitian Farmasi dan Herbal

Pulmonary tuberculosis (TB) is a contagious disease that requires long-term treatment using anti-tuberculosis drugs (OAT). Non-adherence to OAT treatment can lead to treatment failure, drug resistance, and an increase in morbidity and mortality rates. One important strategy to improve treatment outcomes is the proper provision of drug information (PIO) to patients. This study aimed to determine the effect of drug information provision on adherence to OAT use in pulmonary TB patients. This research employed a quantitative method with a quasi-experimental design involving two groups of patients: those who received drug information and those who did not. Adherence levels were measured using the MMAS-8 questionnaire. The results showed a significant difference in adherence levels between the two groups, with the PIO group demonstrating a higher level of adherence. It can be concluded that drug information provision by pharmaceutical personnel has a positive effect on improving patient adherence to OAT. The study recommends integrating PIO into routine clinical pharmacy services in healthcare facilities to support the success of TB treatment.