Jurnal Gizi Klinik Indonesia
Vol 9, No 4 (2013): April

Asupan makan, sindrom metabolik, dan status keseimbangan asam-basa pada lansia

Nurmasari Widyastuti (Program Studi S1 Ilmu Gizi, Fakultas Kedokteran Universitas Diponegoro)
Muhammad Sulchan (Program Studi S1 Ilmu Gizi, Fakultas Kedokteran Universitas Diponegoro)
Andrew Johan (Bagian Biokimia, Fakultas Kedokteran Universitas Diponegoro)



Article Info

Publish Date
01 Apr 2013

Abstract

Background: Metabolic syndrome prevalence increases with age and obesity. The metabolic syndrome is associated with alterations in renal function. Low urine pH has been described as a renal manifestation of the metabolic syndrome. Urine pH is a simple and inexpensive method for determining acid-base status. Recent studies suggest that acid-base status is associated with dietary intake.Objective: To examine relationship between dietary intake, components of metabolic syndrome and urine pH among the elderly.Method: Subjects of this cross-sectional study consist of 49 elderly that were collected consecutively. Height, weight, waist circumference (WC), dietary intake, blood pressure (BP), fasting blood glucose and urine were obtained. Rank Spearman correlation test was used to examine the correlation of components of metabolic syndrome and dietary intake with urine pH. Mann-Whitney test was used to compare the urine pH of the metabolic syndrome group and the normal group. Chi-Square/fisher test was used to calculate prevalence ratio (PR) of metabolic syndrome components to low urine pH. Multivariate analysis was done by multiple linear regression.Results: The mean urine pH of the metabolic syndrome group was 6,06 and significantly lower than the normal group (6,50). WC was the only component of metabolic syndrome that related to urine pH (r=-0,325; p=0,023). Abdominal obesity significantly increases the risk of low urine pH (RP=1,6; p=0,023; CI=1,005-2,442). Urine pH was negatively associated with protein intake and proportion of protein on diet. In multivariate analysis, WC is the most significant factor that predicted urinary pH.Conclusion: Urine acidification is a characteristic of abdominal obesity and the metabolic syndrome. Protein intake and proportion of protein on diet contribute to urine pH.

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Journal Info

Abbrev

jgki

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Nursing Public Health

Description

Jurnal Gizi Klinik Indonesia merupakan jurnal ilmiah nasional terakreditasi yang memuat artikel penelitian (research article) di bidang gizi dan kesehatan, yang terkait aspek gizi klinis, gizi masyarakat, gizi olahraga, gizi molekular, biokimia gizi, pangan fungsional, serta pelayanan dan manajemen ...