Jurnal Kesehatan
Vol 11 No 2 (2018): JURNAL KESEHATAN

FORMULASI DAN UJI EFEKTIVITAS ANTIOKSIDAN KRIM EKSTRAK ETANOL DAUN BOTTO’-BOTTO’ (Chromolaena odorata L.) dengan METODE DPPH

Gemy Nastity Handayany (Universitas Islam Negeri Alauddin Makassar)
Irna Umar (Universitas Islam Negeri Alauddin Makassar)
Isriany Ismail (Unknown)



Article Info

Publish Date
18 Dec 2018

Abstract

A research have been done formulations and test the effectiveness of ethanol leaf extract antioxidant cream botto'-botto (Chromolaena odorata L.) by DPPH method. This study aims to determine the antioxidant activity of cream preparation containing ethanol extract of leaves botto'-botto '(Chromolaena odorata L.) against DPPH and to find out how the concentration of the ethanol extract of leaves botto'-botto' (Chromolaena odorata L.) is effective as an antioxidant the cream preparation. Botto'-botto (Chromolaena odorata L.) was extracted by maceration using 96% ethanol and cream preparations made using various concentration of extract in the formula I, II and III respectively 0.0008%, 0.0016% and 0 , 0024%. Then tested antioxidant activity against DPPH and calculated the average percent reduction of each formula. The results showed an average percent reduction in formula I, II, and III respectively 15.07%, 36.09% and 41.62%. Of the three most effective formulas that antioxidant activity at a concentration of 0.0024% extract.ABSTRAKTelah dilakukan penelitian formulasi dan uji efektivitas antioksidan krim ekstrak etanol daun botto’-botto (Chromolaena odorata L.) dengan metode DPPH. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan sediaan krim yang mengandung ekstrak etanol daun botto’-botto’ (Chromolaena odorata L.) terhadap DPPH dan untuk mengetahui berapa konsentrasi ekstrak etanol daun botto’-botto’ (Chromolaena odorata L.) yang efektif sebagai antioksidan pada sediaan krim. Daun botto’-botto’ (Chromolaena odorata L.) diekstraksi dengan metode maserasi  menggunakan pelarut etanol 96% dan dibuat sediaan krim menggunakan variasi konsentrasi ekstrak pada formula I, II dan III berturut-turut 0,0008%, 0,0016% dan 0,0024%. Kemudian diuji aktivitas antioksidannya terhadap DPPH dan dihitung rata-rata persen peredaman masing-masing formula. Hasil yang diperoleh menunjukkan rata-rata persen peredaman pada formula I, II, dan III berturut-turut 15,07%, 36,09% dan 41,62%. Dari ketiga formula yang paling efektif aktivitas antioksidannya yaitu pada konsentrasi ekstrak 0,0024%.

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Journal Info

Abbrev

kesehatan

Publisher

Subject

Health Professions Medicine & Pharmacology Nursing Public Health

Description

Jurnal Kesehatan is an academic journal that publishes medical and health scientific articles. We regularly publish the issues in June and December. The journal accepts research-based papers, literature/health research regarding of pharmacy, nursing public science and midwifery. This journal ...