<![CDATA[More than half of 50 million worldwide epilepsy patients expected to live in Asia. Public knowledge and attitudes toward epilepsy patients need to be known to prevent social discrimination. Cross-Sectional study was conducted on 223 samples (lecturers, staff and students) at Dian Nuswantoro University. Data collection used questionnaire. The results showed that, 184 respondents(82.5%) had information about epilepsy, 91 respondents (40.8%) knew the cause of epilepsy, and 164 respondents (73.5%) knew that epilepsy was not contagious. While attitudes toward epilepsy patients, 137 respondents (61.4%) are willing to help, 8 respondents (3.6%) will stay away when seeing epilepsy patients experience a seizure attack. Knowledge about epilepsy affect attitudes toward epilepsy patients (p = 0.003; r = 0.182). Ignorance about the transmission of epilepsy (p = 0,007, r = -0,180) and understanding that epilepsy is a curable disease (p = 0,031, r = -0,145) have more influence on low willingness to give help epilepsy patients when they experience seizure attack. In-depth interviews need to be done on future research to gain a deeper information about public’s attitude toward epilepsy patients.Keywords: epilepsy, knowledge, attitude]]>
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