Jurnal Farmasi Indonesia
Vol 11 No 1 (2014): Jurnal Farmasi Indonesia

Sediaan Ekstrak Kering dari Maserat Kombinasi Herba Pegagan (Centella asiatica, [L.] Urban) dan Rimpang Temulawak (Curcuma xanthorrhiza, Roxb.) terhadap Peningkatan Daya Ingat Mencit Putih

Nuryani Nuryani (Unknown)
Suhartinah Suhartinah (Faculty of Pharmacy, Setia Budi University)
Vivin Nopiyanti (Faculty of Pharmacy, Setia Budi University)



Article Info

Publish Date
30 Mar 2014

Abstract

Pegagan (Centella asiatica, [L.] Urban) gives positive effect on the cerebral nerve stimulation, and to smooth the blood transportation to the cerebral vessels. Wild ginger (Curcuma xanthorrhiza, Roxb) potentially protects the cell from oxidative damage and increases appetite. This study was aimed to find out effect of the combination of pegagan herb and wild ginger rhizome extracts in instant preparation to increase the memory. The step through passive avoidance method was used by analysis pretest and posttest latency time interval parameter from the length of time the mice needed to enter the dark compartment from bright compartment. The dose of 0.195 mg Ginkgo biloba as positive control, and 5.2 mg aerosol as negative control, combination of dry extract preparation at 2.6 mg (0.91 mg pegagan extract and 0.98 wild ginger extract), 5.2 mg (1.82 mg pegagan extract and 0.98 wild ginger extract), and 7.8 mg (2.73 mg pegagan extract and 2.94 wild ginger extract) doses. The data was analyzed using two-way ANOVA, followed by Tamhan’s T2 test. The result showed that the combination of macerated pegagan herb and wild ginger rhizome in dry extract preparation can improce memory of the white mice.

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Journal Info

Abbrev

farmasi-indonesia

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Immunology & microbiology Medicine & Pharmacology

Description

Jurnal Farmasi Indonesia (e-ISSN : 2302-4291 dan ISSN : 1693-8615) merupakan jurnal yang dikelola oleh Fakultas Farmasi, Universitas Setia Budi yang terbit sejak Februari 2004 dan terbit 2 kali dalam setahun yaitu periode bulan Maret dan November. Jurnal Farmasi Indonesia menerima naskah tentang ...