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Efek Spermatogenesis Dan Aprodisiaka Herba Purwoceng (Pimpinella alpina K. D. S.) Pasar Terhadap Tikus Putih Jantan Galur Wistar Suhartinah Suhartinah
Jurnal Farmasi Indonesia Vol 8 No 2 (2011): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (108.514 KB) | DOI: 10.31001/jfi.v8i2.44

Abstract

Purwoceng is one of the plants that used traditionally by people in Dieng mountains as aphrodisiac. The use of purwoceng as an aphrodisiac now been extended to other areas and traditional market, usually known as mountain purwoceng, and the part used are the root. The price of purwoceng Dieng is relatively high, while the market purwoceng is relatively affordable. The aim of the experiment was to know the spermatogenesis and aphrodisiac effect of purwoceng herbs infuse from market in Surakarta. Spermatogenesis and aphrodisiac activity test was done using 15 male white mice Wistar strain divided in 3 groups and each group consists of 5 mice. Group I was negative control (water), group II was positive control (purwoceng powder + pasak bumi), group III was purwoceng herbs infuse from market in Surakarta. They were given orally to the mice for 5 days, observed every 2 days. Test of sperm quality was observed on days 0, 2, 4 and 6 which include the number, motility and morphology of spermatozoa. On the 6 th day do weights the testes and seminal vesicles. The aphrodisiac effect was observed behavior of the male white mice by counting the climbing frequency (the male mice climbing on the female mice). The experiment result showed that Purwoceng herb market infuse had an effect on spermatogenesis of male rats and the aphrodisiac on male white mouse wistar strain.
Sediaan Ekstrak Kering dari Maserat Kombinasi Herba Pegagan (Centella asiatica, [L.] Urban) dan Rimpang Temulawak (Curcuma xanthorrhiza, Roxb.) terhadap Peningkatan Daya Ingat Mencit Putih Nuryani Nuryani; Suhartinah Suhartinah; Vivin Nopiyanti
Jurnal Farmasi Indonesia Vol 11 No 1 (2014): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (886.061 KB) | DOI: 10.31001/jfi.v11i1.56

Abstract

Pegagan (Centella asiatica, [L.] Urban) gives positive effect on the cerebral nerve stimulation, and to smooth the blood transportation to the cerebral vessels. Wild ginger (Curcuma xanthorrhiza, Roxb) potentially protects the cell from oxidative damage and increases appetite. This study was aimed to find out effect of the combination of pegagan herb and wild ginger rhizome extracts in instant preparation to increase the memory. The step through passive avoidance method was used by analysis pretest and posttest latency time interval parameter from the length of time the mice needed to enter the dark compartment from bright compartment. The dose of 0.195 mg Ginkgo biloba as positive control, and 5.2 mg aerosol as negative control, combination of dry extract preparation at 2.6 mg (0.91 mg pegagan extract and 0.98 wild ginger extract), 5.2 mg (1.82 mg pegagan extract and 0.98 wild ginger extract), and 7.8 mg (2.73 mg pegagan extract and 2.94 wild ginger extract) doses. The data was analyzed using two-way ANOVA, followed by Tamhan’s T2 test. The result showed that the combination of macerated pegagan herb and wild ginger rhizome in dry extract preparation can improce memory of the white mice.
Pemanfaatan Daun Belimbing Wuluh (Averrhoa bilimbi L) dalam Bentuk Infusa dan Sediaan Celup terhadap Penurunan Berat Badan Inaratul Rizkhy Hanifah; Suhartinah Suhartinah; Opstaria Saptarini
Jurnal Farmasi Indonesia Vol 11 No 2 (2014): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1296.98 KB) | DOI: 10.31001/jfi.v11i2.60

Abstract

Obesity is excess weight due to the accumulation of fat cells. The adverse effects of obesity are high chances for the spread of degenerative diseases and in terms of aesthetic body look unattractive. This research was aimed to use bilimbi leaves as weight loss with varying doses in two dosage forms, namely infusion and tea bag. The test animals used were female white rats were grouped into: negative control group were given 0.5% CMC; positive control group were given xenical® a dose of 2.16 mg / 200 g BB rats; and a test group with a dose preparations bilimbi 5.0 mg/200 g BW, 10 mg/200 g BW, and 20 mg/200 g BW. The treatment were given for 30 days and observed weight. At the end of the treatment, animals dissected after anesthetized. Fats contained around abdominal weighed and the results recorded and compared. Results this study were the bilimbi leaves that has been made in the form of infusions and steeping tea bags in which both had effect as a weight loss in female rats wistar strain.
Penetapan Kadar Omega-3 Undur-Undur Laut (Emerita emeritus) dalam Bentuk Granul, Bubur, dan Mentah secara Kromatografi Gas Angelina Desio Lisarni; Endang Sri Rejeki; Suhartinah Suhartinah
Jurnal Farmasi Indonesia Vol 12 No 1 (2015): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (488.139 KB) | DOI: 10.31001/jfi.v12i1.74

Abstract

Mole crab is the coastal of biological resources are spreading quite extensive and has a high nutrient content, especially omega-3 fatty acids are good for memory. Omega-3 fatty acids consist of linolenic acid, EPA, and DHA. Mole crab is processed into a granule and instant baby puree with a variety of cooking and processing. This study aims to compare the levels of omega-3 content of granule and puree that has been cooked with mole crab raw without cooking. Mole crab that was acquired, cleaned and dried and then processed into mole crab raw, the roasted dried granule, the granule sun dried, instant puree with the addition of a mole crab, and the instant puree without addition of mole crab (placebo). Samples are extracted using soxhlet with solvents chloroform:methanol (2:1). Analysis using gas chromatography with Nitrogen gas as phases of motion. The content of omega-3 was calculated based on the relative percent and analyzed by Shapiro wilk test for normality test. The result of the experiment showed that total content of omega (linolenic acid, EPA, and DHA) extract of mole crab raw was 44,416 g/100 g, extract of granuleroasted was 52,280 g/100 g, extract of granule-sundried was 29,489 g/100 g, extract of mole crabpuree and extract of puree as a placebo was not detected of omega-3.