Jurnal Ilmu Kefarmasian Indonesia
Vol 10 No 2 (2012): JIFI

Pengaruh Fermentasi Sari Kedelai dengan Lactobacillus sp. terhadap Kadar dan Profil Kromatografi Lapis Tipis Genistein serta Formulasinya dalam Granul Efervesen

LATIFAH RAHMAN (UNIVERSITAS HASANUDDIN)
HUSNUL WARNIDA (AKADEMI FARMASI SAMARINDA)
NATSIR DJIDE (UNIVERSITAS HASANUDDIN)



Article Info

Publish Date
30 Sep 2012

Abstract

lsoflavones in soybean and unfermented soybean product are in glycoside form which could not be absorbed by the body and should be hydrolyzed before it is metabolized. Hydrolysis by bacteria producing β-glucosidase occur throughout the gastrointestinal tract. Probiotic microorganisms, like Lactobacillus and bfiidobacterium, have an endogenous enzyme , β-glucosidase that plays an important role in changing the profile of isoflavones during fermentation. The study was to investigate TLC profile and genestein content in fermented soybeanmilk and to formulate the freeze-dried fermented soybeanmilk into effervescent granules preparation. Soybeanmilk was fermented with Lactobacillus sp., and then freeze-dried. The soybeanmilk, before and after fermentation, were then extracted and analyzed by TLC-scanner. The freeze-dried fermented soymilk was prepared into four formulations of effervescent granules with variations in citric acid-tartaric acid ratio. Granules were prepared by the wet method and theirs physical characteristics were evaluated. Extracted granules were analyzed by TLC-scanner. Genistein content in the fermented soymilk has increased 145,32% as compared to the unfermented soymilk. All four effervescent granules have good physical characteristics except that the moisture content were above 0.7%. Formula containing citric acidtartaric acid ratio of (1 : 1) produced effervescent granules with the best physical characteristics.

Copyrights © 2012






Journal Info

Abbrev

jifi

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health

Description

Jurnal Ilmu Kefarmasian Indonesia (JIFI) mainly focuses on a current topic in Pharmaceutical Sciences are also considered for publication by the Journal. Discussions on a topic in Pharmaceutical Sciences, Clinical Sciences, and Social Behaviour Administration. Detailed scopes of articles accepted ...