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Journal of Applied Pharmaceutical Research

joapr
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Published by Creative Pharma Assent

ISSN : - EISSN : 23480335 DOI : 10.18231

Core Subject : Health,

Medicine & Pharmacology

Journal of Applied Pharmaceutical Research (JOAPR) is an official publication of Creative Pharma Assent (CPA). It is an open access, peer review online international journal. JOAPR is primarily focused on multiple discipline of pharmaceutical sciences (Pharmaceutics, Pharmaceutical Technology, Biopharmaceutics, Cosmetic Technology, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy and Phytochemistry, Herbal drugs/ formulations, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest) which publish quarterly. JOAPR also includes evaluation of pharmaceutical excipients & their practical application to research & industry based efforts. The aim of the scientific journal, JOAPR is to present a wide area for the current researchers to share their noble works and ideas in terms of the research papers, review articles and short communications. JOAPR only publish the original research works with a definite innovation and novelty after thorough reviewing. The paper must have a suitable and proper scientific background.

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Articles 5 Documents

Search results for , issue "Vol. 6 No. 1 (2018)" : 5 Documents clear

Synthesis of some dihydropyrimidinone derivatives and study of their anti-inflammatory activity Podilla, Naresh; Choudhury, Tirthankar
Journal of Applied Pharmaceutical Research Vol. 6 No. 1 (2018)
Publisher : Creative Pharma Assent

This research revealed that the numbers of available heterocyclic compounds are mainly focused on nitrogen containing compounds, such as quinazolines, indoles, benzimidazole, quinoxalines, coumarins and pyrimidines etc. A mixture of substituted aldehydes (0.01 mol) like acetyl acetone (method 1) or ethyl acetoacetate (method 2), urea or thiourea (0.01 mol) and lemon juice (0.5 ml) were taken into a round bottom flask and reflux for 1 hour at 800C under continuous stirring. After completion of the reaction the final product was recrystalized for purification. Simultaneously toxicity and anti-inflammatory activity were performed. But in case of using ethyl acetoacetate in method 2, the percentage yield was more as compare to using of acetyl acetone in method 1. So the derivatives obtained from method 2 were selected for further toxicity and anti- inflammatory activities.

Pharmacognostical, physiochemical and phytochemical evaluation of leaf, stem and root of orchid Dendrobium ochreatum Banerjee, Janmajoy; Chauhan, Neelmani; Dey, Biplab K.
Journal of Applied Pharmaceutical Research Vol. 6 No. 1 (2018)
Publisher : Creative Pharma Assent

The present work was aimed to carry out pharmacognosical and phytochemical evaluation of individual root, stem, and leaves of orchid “Dendrobium ochreatum.” The plant was sun dried and was grounded to fine powder using mechanical grinder followed by sieving. The fine powder was collected and subjected to different pharmacognostical studies like fluorescence analysis under uv light at different wavelength. Physiochemical parameters were also evaluated of the dried plant parts like ash values, loss on drying. Each part of plant like root, stem and leaves were separated and subjected to extraction using soxhletion using different polarity solvents i,e hexane, chloroform, ethanol in gradient elution technique. All total nine plant extracts were obtained, phytochemical screening revealed the presence of important phytoconstituents like alkaloid, glycoside, saponins etc whereas only chloroform extracts of stem exhibited the presence of steroid/phytosterol.

Bio-medical waste management in different hospitals of Guwahati and its effect on environment Changmai, Arabinda; Islam, Tofiqul; Nongsiang, Dibarlan; Deka, Manoj Kumar; Saharia, Bhargab Jyoti; Choudhury, Ananta; Dey, Biplab K.
Journal of Applied Pharmaceutical Research Vol. 6 No. 1 (2018)
Publisher : Creative Pharma Assent

Biomedical waste may be defined as the waste which is produced during the diagnosis, research activities, treatment of patients, treatment of animals, production and testing of biological product and including articles as mentioned in schedule I of the Biomedical Waste (Management and handling) (second amendment) Rules 2000, as per Ministry of Environment and Forests notification. Proper treatment, handling, and disposal of biomedical wastes is essential for healthcare infection control program. There may be a high risk of infections in patients due to the poor management of biomedical waste which can lead to antibiotic resistance. It is not only the health of the patient, but also the health of persons who are associated with health care industry equally important. This article speaks about how the hospitals present in Guwahati treat their waste material and the effect of the waste in the environment

Investigation of anti-diabetic potential of Diodia sarmentosa in alloxan-induced diabetic albino rats Rosalie, Ijomone Oghogho; Ekpe, E L
Journal of Applied Pharmaceutical Research Vol. 6 No. 1 (2018)
Publisher : Creative Pharma Assent

Purpose: Natural remedies from medicinal plants are considered to be effective and safe alternative treatments for diabetes mellitus. Diodia sarmentosa (Rubiaceae) commonly called tropical button weed, has been used locally in the treatment of diabetes. This study demonstrates the hypoglycaemic and anti-diabetic activity of the aqueous ethanol extract and ethylacetate fractions of Diodia sarmentosa in alloxan-induced diabetic rats. Methods: 1000g of the leaves (air dried at 250C for 7days) was subjected to extraction using 80% aqueous ethanol and then fractionated with ethylacetate. This gave a percentage yield of 13.299%w/w, 28.30%w/w, and 11.62%w/w for aqueous ethanol extract, ethylacetate soluble and insoluble fraction respectively. Three doses (1000mg/kg, 500mg/kg and 250mg/kg body weight) of the three samples were administered to the test groups while Glibenclamide at dose of 2.5mg/kg body weight was administered to the control group. Comparing the activity of the plant to the standard drug, the activity of all the doses of the aqueous ethanol extract and ethylacetate insoluble fraction was comparable with that of the standard drug (Glibenclamide). Result: As regard to the dose response, the highest activity resides in the highest dose of sample administered (i.e 1000mg/kg body weight) followed by the 500mg/kg and the 250mg/kg body weight (1000mg/kg>500mg/kg>250mg/kg). The aqueous ethanol and ethylacetate soluble fractions caused a significant (p>0.05) reduction in blood glucose of the diabetic rats. Conclusion: Thus, this present study validates the medicinal potential of Diodia sarmentosa in diabetes treatment

Effect of primary packaging on microbiological status of oral solid dosage form Khana, Meenal; Teotia, U. V. S; Siingh, Yogendra
Journal of Applied Pharmaceutical Research Vol. 6 No. 1 (2018)
Publisher : Creative Pharma Assent

The emergence of microbial contaminants in non-sterile drugs caused not only the degradation of many products, but also proved to be a potential risk to consumer health. The aim of this study was to test microbial load of non sterile solid pharmaceutical product and investigate the effects of different packaging system on microbial status of pharmaceutical product. A total of 18 sample of solid dosage form packaged in different packaging were procured from market. All samples have been tested for the presence of specific microorganisms, Total aerobic microbial counts (TAMC) and Total yeast and mold counts (TYMC) using compendial procedures. Out of 18 sample 72.22 % (n=13) had shown microbial growth and only 16 % (n=3) of samples were non-compliant. Sample containing herbal ingredients, were the most heavily contaminated, showing a bacterial load > 104 CFU/g. The result showed that all the tested samples were free from E. coli. There was no significant difference (p>0.05) in microbial load of product packaged in different primary packaging

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Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
japr.editor@gmail.com

Editorial Address
Plot No. 105/42, Opposite electricity sub station, Changorabhata, Raipur (Chhattisgarh), India 492001

Location
,

INDONESIA