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Journal of Applied Pharmaceutical Research
Published by Creative Pharma Assent
ISSN : -     EISSN : 23480335     DOI : 10.18231
Core Subject : Health,
Medicine & Pharmacology
Journal of Applied Pharmaceutical Research (JOAPR) is an official publication of Creative Pharma Assent (CPA). It is an open access, peer review online international journal. JOAPR is primarily focused on multiple discipline of pharmaceutical sciences (Pharmaceutics, Pharmaceutical Technology, Biopharmaceutics, Cosmetic Technology, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy and Phytochemistry, Herbal drugs/ formulations, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest) which publish quarterly. JOAPR also includes evaluation of pharmaceutical excipients & their practical application to research & industry based efforts. The aim of the scientific journal, JOAPR is to present a wide area for the current researchers to share their noble works and ideas in terms of the research papers, review articles and short communications. JOAPR only publish the original research works with a definite innovation and novelty after thorough reviewing. The paper must have a suitable and proper scientific background.
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Articles 3 Documents
 1 
Search results for , issue "Vol. 6 No. 3 (2018)" : 3 Documents clear
Design and optimization of immediate release tablet of salbutamol sulphate by direct compression technique Saha, Suman
Journal of Applied Pharmaceutical Research Vol. 6 No. 3 (2018)
Publisher : Creative Pharma Assent

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (407.472 KB) | DOI: 10.18231/2348-0335.2018.0010

Abstract

This study is about a tablet, which disintegrates or dissolves quickly when placed in the oral cavity. Studies on formulation development of Salbutamol Sulphate Immediate Release Tablet, suitable for manufacturing by direct compression have been carried out. Trial formulations using various excipients were developed and evaluated for various qualities like hardness, friability, disintegration time, content uniformity and dissolution. Study concluded that Immediate Release Tablet of Salbutamol Sulphate can be prepared successfully with added patient benefit and increased consumer satisfaction.
Pharmacognostical, phytochemical and anthelmintic activity of Polygonum muricatum Goswami, Priyanka; Islam, Rajibul; Khongmalai, Everlasting; Sarkar, Bapi Ray; Sen, Saikat; Choudhury, Ananta; Dey, Biplab Kumar
Journal of Applied Pharmaceutical Research Vol. 6 No. 3 (2018)
Publisher : Creative Pharma Assent

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (454.541 KB) | DOI: 10.18231/2348-0335.2018.0009

Abstract

Polygonum muricatum is widely used by the local people of Meghalaya for anthelmintics. An attempt has been made to evaluate the pharmacognostical, preliminary phytochemical and pharmacological parameters of leaves of Polygonum muricatum. The physicochemical constants like moisture content, ash values such as total ash, acid insoluble ash and water soluble ash, extractive values such as water soluble extractive value and alcohol soluble extractive value were determined. The extract obtained by successive solvent extraction was subjected to preliminary phytochemical analysis to find out the presence of compounds. The plant Polygonum muricatum leaves were extracted with the solvent benzene, acetone, ethanol and water by soxhlet apparatus method. The extract was evaluated for anthelmintic activity with Indian earthworm. Ethanol extract of the plant Polygonum muricatum has shown the significant activity.
Assessment of Calamus tenuis fruits extract on blood glucose level elevation and its antibacterial potency Sarkar, Hema; Sharin, Tasfia; Mamun, Muhammad Shamim Al
Journal of Applied Pharmaceutical Research Vol. 6 No. 3 (2018)
Publisher : Creative Pharma Assent

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (953.335 KB) | DOI: 10.18231/2348-0335.2018.0008

Abstract

Investigation of anti-hyperglycemic and antibacterial activity of the fruit extract of Calamus tenuis was carried out. Soxhlet extraction was done using petroleum ether, ethyl acetate and methanol. Anti-hyperglycemic activity was done by Oral Glucose Tolerance Test.The results indicated that methanol extract (500 mg/Kg) showed nearly same potency of blood glucose lowering capacity (4.82 ± 0.730 mmol/L) compared to the glibenclamide (standard drug). Antibacterial activity was investigated using disc diffusion method. Antibacterial tests revealed that S. aureus was resistant to all the solvent extracts. Ethyl acetate and methanol extracts showed moderate antibacterial capacity against both Micrococcus and V. cholerea whereas petroleum ether showed nothing. Zone of inhibition of Ethyl acetate and methanol extracts (200 mg/mL dose) for E. coli were very close to positive control (17.00 ± 0.816 and 18.75 ± 1.258 mm respectively; positive control value was 19.00 ± 1.414 and 21.00 ± 1.414 respectively ). In case of methanol zone of inhibitions were greater than other solvent extracts against all tested bacterial species. From the present research it can be recapitulated that due to the biological activity of C. tenuis fruit it may satisfy as a new candidate for the emergence of medicines.

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