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Acta Pharmaciae Indonesia : Acta Pharm Indo
Published by Universitas Jenderal Soedirman
ISSN : 23378433     EISSN : 26214520     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Journal of Acta Pharmaciae Indonesia is a journal published twice a year by Pharmacy Department, Jenderal Soedirman University, Purwokerto with the Number of ISSN 2337-8433 and E-ISSN 2621-4520. Our journal discusses various pharmaceutical fields in terms of Pharmaceutics & Pharmaceutical Technology, Pharmaceutical Biology, Pharmaceutical Chemistry, and Pharmacology & Clinical Pharmacy.
Arjuna Subject : -
Articles 2 Documents
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Search results for , issue "Vol 13 No 1 (2025): Acta Pharmaciae Indonesia: Acta Pharm Indo" : 2 Documents clear
Hospital pharmacists’ perspectives on diabetes treatment barriers and solutions: A qualitative study from Indonesia Swandari, Mika Tri Kumala; Cholisoh, Zakky; Karuniawati, Hidayah
Acta Pharmaciae Indonesia Vol 13 No 1 (2025): Acta Pharmaciae Indonesia: Acta Pharm Indo
Publisher : Pharmacy Department, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.api.2025.13.1.15716

Abstract

Background: Despite available treatment options, diabetes mellitus (DM) management faces significant barriers affecting patient outcomes. While most research focuses on patient factors, limited attention has been given to healthcare provider perspectives, particularly hospital pharmacists who are key stakeholders in diabetes care. Objective: This study explored treatment barriers and solutions from hospital pharmacists’ perspectives in Indonesia. Methods: This qualitative phenomenological study involved 18 hospital pharmacists at Cilacap Regional General Hospital, Central Java, Indonesia. Participants were selected through purposive sampling and had minimum one-year experience in diabetes patient care. Semi-structured interviews were conducted from January to February 2025, audio-recorded, transcribed verbatim in Bahasa Indonesia, and analyzed using thematic analysis. All interviews were conducted in Bahasa Indonesia and participant quotes were translated to English while preserving original meaning and cultural context. Results: Analysis of three predetermined barrier themes revealed: adverse drug reactions (ADRs) (particularly metformin-related gastrointestinal effects and insulin-associated hypoglycemia), medication non-adherence (influenced by feeling healed, treatment boredom, age-related denial, and therapy burden), and monthly follow-up challenges (geographic barriers, transportation difficulties, physical limitations, and insufficient family support). Pharmacists proposed comprehensive solutions including patient and family education, interprofessional collaboration, technology integration through WhatsApp support, and flexible monitoring approaches. Conclusion: Pharmacist-identified barriers operate as interconnected system components requiring multi-level interventions. Evidence-based solutions emphasizing education, collaboration, family engagement, and technological support can enhance diabetes management outcomes while respecting cultural contexts and resource constraints.
Extraction techniques for phenolic compounds from Zingiber officinale: a review of traditional, microwave-assisted, and ultrasound-assisted methods Febriani, Ni Kadek Dwi; Susanti, Ni Made Pitri; Dewi, Luh Putu Mirah Kusuma
Acta Pharmaciae Indonesia Vol 13 No 1 (2025): Acta Pharmaciae Indonesia: Acta Pharm Indo
Publisher : Pharmacy Department, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.api.2025.13.1.17252

Abstract

Background: The rhizome of Zingiber officinale (ginger) is widely recognized for its pharmacological properties, particularly its antioxidant activity, which is largely attributed to phenolic compounds such as gingerol, shogaol, paradol, and zingerone. Efficient extraction of these compounds requires suitable techniques to maximize yield while maintaining compound stability. Objective: This review aims to evaluate extraction techniques for phenolic compounds from ginger rhizomes, comparing traditional and modern approaches, and to identify methods that produce the highest total phenolic content (TPC). Methods: A literature review was conducted on original research articles published between 2015 and 2025 that reported phenolic extraction from Z. officinale using maceration, soxhlet extraction, reflux, microwave-assisted extraction (MAE), or ultrasound-assisted extraction (UAE). Articles were retrieved from Google Scholar and ScienceDirect databases and assessed against defined inclusion and exclusion criteria. Results: Six eligible studies were included, revealing substantial methodological heterogeneity that complicates direct method comparisons. UAE with 50% ethanol produced the highest TPC (155.19 ± 2.81 mg GAE/g dry weight), followed by Soxhlet extraction (31.10 ± 0.28 mg GAE/g) and MAE (27.89 ± 1.99 mg GAE/g). Reflux and maceration yielded comparatively lower TPC values, with results influenced by solvent type, concentration, temperature, and extraction time. Conclusion: UAE with 50% ethanol is the most effective technique for extracting phenolic compounds from ginger, offering both high yield and compound stability. MAE, while producing lower yields, remains advantageous for its shorter extraction duration.

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