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International Journal of Cardiovascular Practice

ijcp
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Published by Shahid Beheshti University of Medical Sciences

ISSN : 24767174 EISSN : 2476468X DOI : -

Core Subject : Health,

Medicine & Pharmacology

International Journal of Cardiovascular Practice(IJCP) is an international quarterly journal dedicated to a broad spectrum of topics in cardiology. All manuscripts must be prepared in English, and are subject to a rigorous and fair peer-review process. Accepted papers will immediately appear online followed by printed hard copy.

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Articles 198 Documents

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Correlation of platelet indices with TIMI frame count in patients undergoing primary PCI due to ST-segment elevation myocardial infarction Salehi, Ayoub; Namazi, Mohammad Hasan; Safi, Morteza; Vakili, Hossein; Saadat, Habibollah; Alipour Parsa, Saeed; Akbarzadeh, Mohammad Ali; Moshtaghi, Ameneh; Khaheshi, Isa
International Journal of Cardiovascular Practice Vol 4, No 3 (2019)
Publisher : International Journal of Cardiovascular Practice

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (605.876 KB)

Introduction: Given the fundamental role of platelet indices in the development of atherosclerotic plaque, these indices may play a predictive role for the occurrence of disturbed coronary reperfusion. The present study evaluated the relationship between platelet indices and coronary reperfusion status based on TIMI frame count.Methods: This cross-sectional study was conducted on 98 consecutive patients with STEMI who were candidate for primary PCI at Modarres Hospital in Tehran between January 2016 and January 2018. Venous samples were extracted from all patients before primary PCI. To assess the condition of coronary reperfusion after primary PCI, TIMI frame count related to culprit artery in acute myocardial infarction was determined.Results: The TIMI frame count was positively associated with platelet count (r = 0.320, p = 0.001) and more strongly with platelet to lymphocyte ratio (r = 0.375, p < 0.001), but not with other platelet indices such as PDW, MPV, or PLCR. According to the ROC curve analysis, platelet to lymphocyte ratio was introduced as a valuable parameter for differentiating complete from disturbed reperfusion (AUC = 0.735, 95%CI: 0.613 ? 0.858, P = 0.001). The best cutoff value for platelet to lymphocyte ratio in predicting disturbed reperfusion was 146.5 yielding a sensitivity of 81.8% and a specificity of 60.5%. However, other platelet indices could not present this predictive role. Conclusion: From different platelet indices, the platelet to lymphocyte ratio with predictive accuracy and sensitivity predict coronary perfusion impairment based on the increase in TIMI frame count.

Idiopathic Chylopericardium: A case Report and Breif Review of Literature Haraka, Majda; Mourid, Monia El; Boutaleb, Amine Mamoun; Khay, Khadija; Azzouzi, Leila; Habbal, Rachida
International Journal of Cardiovascular Practice Vol 4, No 3 (2019)
Publisher : International Journal of Cardiovascular Practice

Chylopericardium is the accumulation of chylous fluid in the pericardial space. Many etiologies can be found and the treatment depends on the etiology and remains unclear. This rare entity needs some tests to determine its causes. Diagnosis is based on many tools; the pericardial biopsy puncture and lymphoscintigraphy are the most important ones. The treatment requires low fat diet, lipid lowering therapy and surgery in some cases. We here report the first case in the IBN ROCHD university hospital?s Cardiology department of Casablanca, Morocco. It deals with a 32-year-old patient who consulted for dyspnea exacerbation for 18 months, becoming at rest. Chest X-ray and echocardiography were performed discovering pericardial effusion. Pericardiocentesis was performed to confirm the nature of liquid and lymphoscintigraphy showed no abnormal communication between the thoracic duct and pericardium.

Impact of Cardiopulmonary Resuscitation on Cardiac Transplantation outcome Mojtabaee, Meysam; Naghashzadeh, Farah; Ghorbani, Fariba; Ghafarian, Shahrzad; Shahryari, Shagin; Sadegh Beigee, Farahnaz
International Journal of Cardiovascular Practice Vol 4, No 3 (2019)
Publisher : International Journal of Cardiovascular Practice

Introduction: Donor heart shortage limits heart transplantations programs while the number of patients waiting for cardiac transplant continues to increase. Optimizing the use of all available donor hearts is a vital key to reduce waiting list mortality. Among different extended criteria, prolong cardiopulmonary resuscitation (CPR), i.e. more than 20 min, has been considered under doubt to be a selection criterion in donor selection. The aim of this study was to compare the outcomes of heart transplantation from cardiopulmonary-resuscitated donors to those who received hearts from donors who did not require cardiopulmonary resuscitation.Methods: This study was a retrospective analysis of adult heart transplantation program in Masih Daneshvari Hospital in Tehran, Iran from 2010 to 2019. Donors and recipients? demographics, cause of end-stage heart disease and brain death, duration of hospitalization for both donors and recipients and also the duration of cardiopulmonary resuscitation and other factors related to it were investigated. Qualitative variables were compared using Chi-square test. Quantitative variables were compared using T-test. Patient and graft survival rates were calculated using the actuarial method and compared using Wilcoxon's test.Results: Among 92 recipients, 39 were transplanted with cardiac grafts from CPR-suffering donors. There were no significant differences regarding sex, age, donor and recipient hospitalization periods, early rejection and 1-year-survival rate considering CPR and non-CPR grafts. However, we detected a strong negative correlation between the duration of CPR and 3-year-survival rate (P = 0.02 and R-value = -0.62) and also its association with post-transplant arrhythmias (P = 0.04).Conclusion: There is a negative possible influence of long-lasting CPRs (especially more than 20 minutes) in midterm survival and post-transplant complications.

STâ€“Segment elevation: Not always an acute coronary syndrome Costa, Érico; Meireles, Elsa; Rodrigues, Catarina; Teixeira, Tiago Godinho; Silva, Dulce
International Journal of Cardiovascular Practice Vol 2, No 1 (2017)
Publisher : International Journal of Cardiovascular Practice

Cardiac tumors can be primary or metastatic, the latter being more frequent and usually of pulmonary or hematologic origin. These patients? clinical signs are non-specific and the electrocardiogram (ECG) can assume many patterns, among which, ST-segment elevation. Nevertheless, associated occlusion of the coronary arteries is rare in these situations.We present a 79-year-old woman with a history of pulmonary neoplasia who was admitted to the emergency department due to atypical chest pain, cough and worsening dyspnea in the previous 3 days. The ECG revealed an ST-segment elevation in the anterolateral and inferolateral leads, despite normal blood work, namely normal troponin. Due to the disparity between the patient?s symptoms and the ECG findings, a decision was made not to proceed to primary angioplasty, but to further investigate with echocardiography, which revealed a mass localized in the anterolateral and inferolateral left ventricle walls, confirmed by computed tomography. The patient was admitted in the medical ward for symptomatic management. Her clinical condition gradually deteriorated due to the disease?s natural evolution and she died two weeks later.This case highlights the importance to keep in mind differential diagnoses to acute coronary syndromes, when a ST-segment elevation is encountered on an ECG.

DIFFERENT POLYMORPHISMS OF PLACENTAL GROWTH FACTOR (PLGF) GENE IN IRANIAN WOMEN'S POPULATION WITH PRE-ECLAMPSIA Pourroostaei Ardakani, Parisa; Ramezani, Arezoo; Piravar, Zeinab; Asgharimoghadam, Nastaran; Behzadi, Roudabeh; Jafari Fesharaki, Mehrdad
International Journal of Cardiovascular Practice Article in Press
Publisher : International Journal of Cardiovascular Practice

Introduction: Preeclampsia is a complication affecting pregnant women worldwide, which leads to maternal and fetal morbidity and mortality. Due to the importance of mutations in the PLGF (Placental Growth Factor) gene and the association with the incidence of preeclampsia, this study aimed to evaluate the association of polymorphisms of the PLGF gene with the prevalence of preeclampsia in Iranian women.Methods: Fifty pregnant women with pre-eclampsia diagnosis and 50 healthy pregnant women for determination of genotypes rs1464547123, rs12411, rs1399853427, and rs1312670436 were evaluated using the Sanger sequencing method.Results: There was no significant difference in the frequency of alleles ofrs1464547123, rs1399853427 and rs1312670436 polymorphisms between case and control groups (P > 0.05), but the rate of recessive allele A in rs12411 polymorphism was significantly higher in the case group than in the control group (case = 24%, control = 8%, P-Value = 0.04), while the frequency of the allele T in the control group was higher than that of the patient group (case = 76%, control = 92%, P-Value = 0.04) The frequency of AT genotype in the patient group was a none significantly higher than the control group (case = 8%, control = 4%, P-Value = 0.1) and the frequency of AA genotypes in the case group was none significantly higher than that of the control group (case = 16%, control = 4%, P-Value = 0.1).Conclusions: The results revealed that polymorphism rs12411 of the gene encoding PLGF has a significant difference among individuals with and without pre-eclampsia and can affect the incidence of pre-eclampsia among Iranian women.

PULMONARY CAPILLARY HEMANGIOMATOSIS: A RARE CAUSE OF PULMONARY ARTERIAL HYPERTENSION, PRESENTING AS SUPRAVENTRICULAR TACHYCARDIA Dattaprasad, Ganganpalli; Chandra, Umesh Kumar; Vishwakarma, Sumit Kumar; Pandey, V.P.; Dubey, Sanjay
International Journal of Cardiovascular Practice Article in Press
Publisher : International Journal of Cardiovascular Practice

With a prevalence of less than 1/million, Pulmonary Capillary Hemangiomatosis is a rare disorder of capillary proliferation in the alveolar septae leading to pulmonary arterial hypertension and mimics pulmonary veno-occlusive disease.

PREVALENCE OF NON-THROMBOEMBOLIC INCIDENTAL FINDINGS ON COMPUTED TOMOGRAPHY-PULMONARY ANGIOGRAPHY FOR PULMONARY Bozorgmehr, Rama; Pishgahi, Mehdi; Mohaghegh, Pegah; Bayat, Marziye; Khodadadi, Parastou; Ghafori, Ahmadreza
International Journal of Cardiovascular Practice Article in Press
Publisher : International Journal of Cardiovascular Practice

Introduction: Computed Tomography-Pulmonary Angiography (CTPA) is a noninvasive imaging modality for direct diagnosis of pulmonary thromboembolism. The potential advantage of CTPA is possible alternative and incidental findings in cases that PTE is ruled out. This study was performed to determine the prevalence of incidental findings in CTPA in patients suspected to have PTE.Methods: This cross-sectional retrospective study was performed in patients with suspected PTE admitted to Shohada-e-Tajrish Hospital in 2014 and 2015 and underwent CTPA for final diagnosis. Incidental findings in CTPA and associated clinical symptoms were assessed.Results: According to CTPA performed in 188 patients, PTE was diagnosed in 61 cases (32.4%). Prevalence of incidental abnormal findings in the two groups with and without PTE were 93.7% and 90.9%, respectively. The most common incidental finding was pleural effusion (42%). There was no significant association between clinical symptoms and incidental findings in CTPA in patients with suspected pulmonary embolism (P > 0.05). The only significant finding was association between lung mass and tachypnea (P=0.007).Conclusion: In patients with primary clinical symptoms of suspected pulmonary embolism, in most cases there was a wide range of incidental findings and simultaneous pathologies in CTPA mimicking the primary symptoms of pulmonary embolism. However, in this study there was no significant association between clinical symptoms and incidental findings. Determination of definite indications of CTPA in patients with suspected pulmonary embolism is necessary.

EFFECT OF RETROGRADE AUTOLOGOUS PRIMING ON CLINICAL OUTCOME OF CARDIOPULMONARY BYPASSING ON PATIENTS UNDERGOING CORONARY ARTERY BYPASS GRAFTING Rafiee, Musa; Zia Toutounchi, Mohammad; Yazdani, Rezvan; Mohammadi, Nooredin
International Journal of Cardiovascular Practice Article in Press
Publisher : International Journal of Cardiovascular Practice

Introduction: Cardiopulmonary bypass is a standard and low mortality-associated method used across the world. This method allows cardiac surgery to be performed in a bloodless environment. The study aimed to compare Conventional priming and Retrograde autologous prime (RAP) on patients undergoing coronary artery bypass grafting (CABG).Methods: The study population was patients undergoing CABG using cardiopulmonary bypass in Rajaei Hospital, of whom 80 patients were selected by simple random sampling convenience sampling and then were randomly assigned to two groups: Conventional priming and RAP. Demographic information, blood components transfused in the operating room and the intensive care unit, ejection fraction (EF) of left ventricle and changes in blood gases were collect.Results: The mean requirement for red blood cell transfusion bags to the patient during surgery was lower in the RAP group than the conventional priming group (P = 0.002). But the difference after surgery in both groups was not significant statistically (P = 0.2). The difference amount of platelet transfusion during operation the difference was not statistically significant (P = 0.4). The difference postoperative platelet transfusion was not statistically significant (P = 0.7). The fresh frozen plasma transfusion during surgery in the RAP group lower than the usual prime group, but the difference was not statistically significant (P = 0.406). The Fresh frozen plasma (FFP) transfusion after surgery in the two groups was not statistically significant (P = 0.217).Conclusion: RAP is compared with conventional priming a safe and low-cost technique in reducing the priming volume of the CPB system, causes less hemodilution, and reduces the need for intra- and postoperative blood transfusion. Therefore, it is recommended to consider RAP as an effective and low-cost technique of priming Cardiopulmonary bypass circuits.

CARDIOGENIC SHOCK FOLLOWING ACUTE MYOCARDIAL INFARCTION: A RETROSPECTIVE OBSERVATIONAL STUDY Sadeghi, Roxana; Kachoueian, Naser; Maghsoomi, Zohreh; Sistanizad, Mohammad; Soroureddin, Zahra; Akbarzadeh, Mohammad Ali
International Journal of Cardiovascular Practice Article in Press
Publisher : International Journal of Cardiovascular Practice

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (750.902 KB)

Introduction: Cardiogenic shock is a sudden complication that occurs in 5 to 10% of patients with acute myocardial infarction. According to statistics, mortality and morbidity from this event, despite all hospital care, are approximately 70-80%.Methods: This study was conducted over three years (2012 to 2014) in 28 cases of acute myocardial infarction, which was complicated by cardiovascular shock, before or after admission. We compared the outcomes of patients according to the treatment strategy, thrombolytic therapy, primary percutaneous coronary intervention (PCI), or other medical stabilization. The 30-day follow-up was the first endpoint, and the 3- month follow up was the second endpoint of the study.Results: 28 patients with cardiogenic shock included in this study. The mean (± SD) age of the patients was 62.99 ± 13.99 years. The median time to the onset of shock was 648.75 ± 1393.58 minutes after infarction. Most of the patients who underwent coronary angiography had 3-vessel or left main involvement. Two patients missed in follow up and five (80%) patients who received thrombolytic therapy passed away. Nine (100%) patients in the medical stabilization group and six patients (50%) underwent primary PCI group passed away too. The mortality in the primary PCI group was significantly lower than the other groups (P = 0.04).Conclusion: Although cardiogenic shock is a potential risk of early death, it is important that the thrombolytic in these patients doesn't increase survival and the primary PCI is more effective than thrombolytic agents.

ACUTE MYOCARDITIS MIMICKING AN ACUTE CORONARY SYNDROME: CASE REPORT AND MINI-REVIEW OF THE LITERATURE Talhi, Fatima Ezzahraa; Elmourid, Monia; Maaroufi, Anass; Qechchar, Zakaria; Arous, Salim; Bennouna, El Ghali; Azzouzi, Leila; Habbal, Rachida
International Journal of Cardiovascular Practice Article in Press
Publisher : International Journal of Cardiovascular Practice

Acute myocarditis is often a challenging diagnosis due to a lack of specific clinical or paraclinical signs. It can be presented by a severe chest pain and localized ST elevation on Electrocardiogram, in rare cases, misleading the diagnosis towards acute coronary syndrome. After routine coronary angiography, a cardiac magnetic resonance imaging is imposed to correct the diagnosis towards acute myocarditis. We report the observation of a 19 year-old Moroccan male admitted to the cardiology department of IBN ROCHD University hospital of Casablanca, for acute myocarditis misdiagnosed initially as an acute myocardial infarction ST elevation and confirmed by cardiac magnetic resonance imaging.

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