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INDONESIA
Buletin Farmatera
Published by Universitas Muhammadiyah Sumatera Utara
ISSN : 2528410X     EISSN : 2528410X     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Arjuna Subject : -
Articles 6 Documents
 1 
Search results for , issue "Vol 5, No 1 (2020)" : 6 Documents clear
PROFILE OF MICROORGANISMS CAUSING VAGINAL DISCHARGE IN REPRODUCTIVE WOMEN AT DR. PIRNGADI HOSPITAL IN MEDAN Iqrina Widya Zahara; Irma Damayanti Roesyanto; Sri Amelia
Buletin Farmatera Vol 5, No 1 (2020)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (481.09 KB) | DOI: 10.30596/bf.v5i1.3934

Abstract

Leucorrhoea or Fluor albus or leukorrhea vaginal discharge is the discharge of fluid other than blood from the vaginal canal out of the ordinary, either smelling or not, and accompanied by local itching. There are two factors that cause leucorrhoea, namely endogenous factor such as abnormalities in the vagina and exogenous factor which are infection and non-infection. The aim of this study is to find the profile of microorganisms causing vaginal discharge in reproductive women. This is a descriptive study with cross-sectional method conducted at the Skin and Genital Polyclinic of the Sexually Transmitted Infectious Disease Division and the Obstetrics and Gynecology Clinic of Pirngadi Hospital, Medan. Populations that have met the inclusion and exclusion criterias were included in the study. Vaginal discharge samples will be sent to the microbiology laboratory and the parasitology laboratory of faculty medicine of University of North Sumatera to examine the gram staining, KOH staining, bacterial and fungal cultures and wet preparations for parasites. Out of a total of 50 people, the majority of the sample are in aged 31-40 years, with a history of high school education and working women. The most types of vaginal discharge are pathological (84%) and the most common cause of vaginal discharge is a fungal infection by Candida sp (90%) followed by bacterial infection by Staphylococcus aureus (64.8%) and Klebsiella (20.3%)
ANTIHIPERGLICEMIC THERAPY COMPLIANCE WITH HbA1C LEVELS IN TYPE 2 DIABETES MELLITUS PATIENTS AMONG PEKANBARU PROLANIS PARTICIPANTS Dimas Pramita Nugraha; Eni Karmila Asni; Ligat Pribadi Sembiring Pribadi Sembiring
Buletin Farmatera Vol 5, No 1 (2020)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v5i1.4203

Abstract

One of the pillars in the management of Type 2 Diabetes Mellitus (DM) is pharmacotherapy, i.e. the use of antihyperglycemic drugs. Success in DM management is influenced by patient compliance to the pharmacotherapy given. One indicator of controlling Type 2 DM is HbA1c levels. This study aimed to analyze the relationship between antihyperglycemic therapy compliance and the HbA1c levels in Type 2 DM patients in the Chronic Disease Management Program in Pekanbaru. Method. This was a cross-sectional study. Samples were taken by consecutive sampling method. Laboratory examination was carried out to obtain HbA1c levels, the value of which was categorized controlled if <7%. The compliance with the use of antihyperglycemic drugs was assessed using Medication Possession Ratio (MPR). Patients were considered compliant if they had an MPR of ≥80%. Data were analyzed using the Fisher Exact test. Results. Most of the 48 patients had uncontrolled HbA1c levels (87,5%). The level of non-compliant patients was also very high (91,7%). This study showed a significant relationship between pharmacotherapy compliance and HbA1c levels (p <0.05). Discussion. There was a relationship between pharmacotherapy compliance and the level of HbA1c in Type 2 DM patients.  Physicians should pay more attention to patients with low compliance as it may increase the risk to a high HbA1c level
CORRELATION OF NUTRITIONAL STATUS WITH THE INCIDENCE OF ACUTE DIARRHEA IN ONE TO THREE YEARS CHILDREN AT AMPLAS HEALTH CENTER IN 2015 Ashry Ramadhana Ginting; Amelia Eka Damayanty
Buletin Farmatera Vol 5, No 1 (2020)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (328.907 KB) | DOI: 10.30596/bf.v5i1.2327

Abstract

Nutritional status is a body condition as a result of food consumption and infection status. Nutritional status can be a risk factor of diarrhea. The aim is to determine the correlation of nutritional status with the occurrence of acute diarrhea in children beetween one to three years old at Puskesmas Amplas in 2015. This research is an analytic method of cross sectional and analysis of Chi Square. Using a secondary data from medical records of Puskesmas Amplas. All of bad-nourished respondence often suffering an acute diarrhea within one month. A well-nourished respondence who often suffer from acute diarrhea is 16,7%, and all of obese respondence often suffering an acute diarrhea. There is a correlation between the nutritional status with the occurrence of acute diarrhea with p value is 0,000 (p<0,05) in this research
THE EFFECT OF WORK STRESS ON NURSE PERFORMANCE IN THE INPATIENT WARDS TANJUNG PURA HOSPITAL ON 2016 Nopa, Ika; Zulfendri, Zulfendri; Fauzi, Fauzi
Buletin Farmatera Vol 5, No 1 (2020)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (418.832 KB) | DOI: 10.30596/bf.v5i1.2679

Abstract

Nursing care in a hospital is an integral part of health service. A nurse has constant contact with patients within 24 hours, and her work demands can potentially cause stress. The main purpose of the research was to find out the influence of work stress on nurses' performance in the Inpatient Wards.The research was a survey with an explanatory research method to find out the influence of work stress on nurses' performance in the Inpatient Wards of RSUD (Regional General Hospital) Tanjung Pura. The population was 63 nurses in the Inpatient Wards, and all of them were used as the samples since their numbers were relatively small. The data were gathered by conducting in-depth interviews and reporting data were obtained from the hospital. The gathered data were analyzed by using a linear regression statistic test.The result of the research showed that 77.8% of the respondents had moderate performance, 14.3% of the respondents had a good performance, and 7.9% of the respondents had a bad performance. It was also found that the variable of work stress influenced the performance at p-value = 0.00001.It is recommended that the hospital management pay attention to the nurses? condition in each Inpatient Ward. On the other hand, the hospital management should give special attention to the work stress undergone by the nurses in the Inpatient Wards
COMPARISON OF THE EFFECTIVENESS BETWEEN RED GALANGAL RHIZOME'S (Alpinia purpurata k.schum) EXTRACT AND KETOCONAZOL 2% TO INHIBIT GROWTH OF DERMATOPHYTE ​​FUNGI IN VITRO Pangestuti, Dewi; Harris, Bilkes; Rahman, Tuti Khairani
Buletin Farmatera Vol 5, No 1 (2020)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (802.324 KB) | DOI: 10.30596/bf.v5i1.3091

Abstract

Red galangal rhizome (Alpinia purpurata k. Scum) has a larger size and has more therapeutic properties. Red galangal has compounds that can inhibit fungal growth namely flavonoids and saponins which can interfere with the function of the fungal cytoplasmic membrane, besides that they can cause leakage and aggregation of the outer cell membrane, which can inhibit the growth of dermatophytes. This study is a laboratory experimental study, using antifungal activity test with diffusion method using paper discs to see the comparison of the red galangal extract effectiveness and ketoconazole 2% on the growth of dermatophytes fungi Microsporum canis, Microsporum gypseum, and Trichophyton metagrophytes by measuring the inhibition zone around the fungal colonies. The concentrations of red galangal extract used were 10%, 20%, 30%, 40%, and 50% and used 2% ketoconazole as control. The data was analyzed using the One Way Anova test. Result of this study shown that all concentrations without 10 % of red galangal have inhibited zones of Microsporum canis, Microsporum gypseum, and Trichophyton metagrophytes but not better than ketoconazole 2 % activities.
COMPARISON OF ANTIOXIDANT AND ANTI-TYROSINASE ACTIVITY BETWEEN BLACK SOYBEAN (GLYCINE MAX (L.) MERR.) AND DAIDZEIN Delken Kuswanto; I Nyoman Ehrich Lister; Ermi Girsang; Ali Napiah Nasution; Wahyu Widowati
Buletin Farmatera Vol 5, No 1 (2020)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (592.818 KB) | DOI: 10.30596/bf.v5i1.3492

Abstract

Free radicals in the body will increase with excessive of ultraviolet (UV) light exposure, induce oxidative stress with the formation of Reactive Oxygen Species (ROS). A visible effect on skin tissue known as photoaging, including the process of melanogenesis catalyzed by the tyrosinase enzyme, risked for pigmentation or melanoma disorder.The use of natural ingredients has been widely used by the community to prevent the aging process. Natural compounds from a plant can be a source of antioxidants and have anti-aging abilities through inhibition of the tyrosinase enzyme. Black soybean (Glycine max (L.) Merr.) are high in isoflavone compound, one of which is daidzein.This study evaluates the antioxidant and anti-aging potential of black soybean extract with daidzein. Antioxidants using the DPPH method and anti-aging tests carried out, namely the inhibition of the tyrosinase enzyme, are very important in the aging process.Daidzein has an IC50 value of DPPH scavenging activity around 109.34±2.80 µg/mL lower than black soybean extract with 116.52±2.50 µg/mL. Results on tyrosinase enzyme inhibition activity, black soybean extract had an IC50 value of 70.71±1.83 µg/mL lower compared to daidzein with 72.65±2.81 µg/mL. In contrast to the better antioxidant activity of daidzein, the black soybean extract are more potential to inhibit the enzyme tyrosinase

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