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All Journal Buletin Farmatera Indonesian Food Science and TechnologyJournal Owner : Riset dan Jurnal Akuntansi Jurnal Riset Hesti Medan Akper Kesdam I/BB Medan Best Journal (Biology Education, Sains and Technology) Nommensen Journal of Medicine Pengmasku Wahana Jurnal Ilmiah Ilmu Terapan Universitas Jambi Jurnal Kedokteran STM (Sains dan Teknologi Medik) Jurnal Kedokteran Ibnu Nafis Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara International Journal of Sustainability in Research (IJSR) Medicina Biomedica Journal Medistra Medical Journal (MMJ)
Pangestuti, Dewi
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PENGARUH PEMBERIAN AIR PERASAN JERUK NIPIS (CITRUS AURANTIFOLIA SWINGLE) TERHADAP KADAR KOLESTEROL PADA MENCIT HIPERKOLESTEROLEMIA Pangestuti, Dewi
Jurnal Riset Hesti Medan Vol 4, No 1 (2019)
Publisher : Akademi Keperawatan Kesdam I/Bukit Barisan Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (427.32 KB) | DOI: 10.34008/jurhesti.v4i1.88

Abstract

Lime (Citrus Aurantifolia) contains of main flavonoid in limes, that is herperidin. Hesperidin can help reducing total Cholesterol level and has the property of hypercholesterolemic. Hypercholesterolemia is the main factor independent risk factor of coronary heart disease (CHD). This study intend to determine whether or not the effect od water lime extract orally with cholesterol level in the hypercholesterolemia mice. This isi an experimental study designed following randomize control design and post test only control group design by using 24 mice (Mus musculus) adult male strain DD Webster divided into 4 groups: control group (P0) that Given adlibitum, (P1) that given hypercholesterolemia 0,2 cc, (P3) that given hypercholesterolemia 0,2 cc and water lime extract 0,3 cc by gastric sonde once a day for 15 days. In the day46 mice are done neck dislocation. Data result was analyzed by One Way- Anova test and continuous and continued with post-hoc test. Result of this study showed that giving of water lime extract 0,3 cc orally per mice could reduced cholesterol level of mice hypercholesterolemia than giving water lime extract 0,1 cc orraly per mice. 
COMPARISON OF THE EFFECTIVENESS BETWEEN RED GALANGAL RHIZOME'S (Alpinia purpurata k.schum) EXTRACT AND KETOCONAZOL 2% TO INHIBIT GROWTH OF DERMATOPHYTE ​​FUNGI IN VITRO Pangestuti, Dewi; Harris, Bilkes; Rahman, Tuti Khairani
Buletin Farmatera Vol 5, No 1 (2020)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (802.324 KB) | DOI: 10.30596/bf.v5i1.3091

Abstract

Red galangal rhizome (Alpinia purpurata k. Scum) has a larger size and has more therapeutic properties. Red galangal has compounds that can inhibit fungal growth namely flavonoids and saponins which can interfere with the function of the fungal cytoplasmic membrane, besides that they can cause leakage and aggregation of the outer cell membrane, which can inhibit the growth of dermatophytes. This study is a laboratory experimental study, using antifungal activity test with diffusion method using paper discs to see the comparison of the red galangal extract effectiveness and ketoconazole 2% on the growth of dermatophytes fungi Microsporum canis, Microsporum gypseum, and Trichophyton metagrophytes by measuring the inhibition zone around the fungal colonies. The concentrations of red galangal extract used were 10%, 20%, 30%, 40%, and 50% and used 2% ketoconazole as control. The data was analyzed using the One Way Anova test. Result of this study shown that all concentrations without 10 % of red galangal have inhibited zones of Microsporum canis, Microsporum gypseum, and Trichophyton metagrophytes but not better than ketoconazole 2 % activities.
Analysis of Incompatible Crossmatch Results Based on Autoimmune Haemolytic Anemia Characteristics (Aiha) at Pmi Semarang City in 2021-2022 syarifah, Syarifah; Prasetyaswati, Betty; Pangestuti, Dewi
International Journal of Sustainability in Research Vol. 1 No. 1 (2023): May 2023
Publisher : MultiTech Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59890/ijsr.v1i1.129

Abstract

Background: Crossmatch with positive Major, positive Minor, positive Auto Control results, a DCT examination is carried out whose positive results are suspected to indicate an AIHA diagnosis in the patient, if given there must be a letter from the doctor treating the patient requesting blood to be transfused. Method : Observational descriptive design with a cross-sectional approach, the results of incompatible crossmatch of autoimmune haemolytic anemia patients in 97 patients with elderly characteristics at PMI Semarang City in January 2021-December 2022. Data collection methods using secondary data were analyzed using univariate and bivariate with Microsoft Excel 2010 and SPSS Version 26 Results: Most crossmatch incompatibilities were found at age > 56 years (66%), Major Positive (99%), Positive AutoControl (99%), Diagnosis of Autoimmune Haemolytic Anemia (AIHA). The results of the bivariate test showed that the major crossmatch was -0.073 while the Auto Control was 0.142. This indicates that age does not affect the results of incompatible crossmatches. Conclusion: Most of the needs were met by female sex as many as 118 patients with positive rhesus blood type and dominated by the age of 1-10 years. Analysis of incompatible crossmatch results based on the characteristics of patients with autoimmune haemolytic anemia at PMI Semarang City in 2021-2022 with the result that age can affect the results of incompatible crossmatches.
Rahasia Di Balik Kesuksesan: Strategi Cerdas UMKM Kuliner Dalam Mengelola Risiko Pangestuti, Dewi; Senny, Nila; Aurel, Princes; Anayya, Miska; Varga, Fatimah; Putri, Dina Rachma; Nafilaty, Najwa Laila
Pengmasku Vol 4 No 1 (2024)
Publisher : PT WIM Solusi Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54957/pengmasku.v4i1.1064

Abstract

The objective of this community service activity is to evaluate the risk management practices employed by Cahaya Sop Ikan MSME in order to ascertain the efficacy of the strategies utilized to address the inherent risks associated with this culinary enterprise. A qualitative approach is employed in this analysis to identify and assess the various risks faced by the business, including those related to inventory, competition, pricing, reputation, food safety and quality, and financial risk. The results of this abdimas activity demonstrate that, despite the considerable challenges faced by MSMEs, business owners are capable of effectively mitigating these risks through the implementation of strategic measures, including competitive pricing and quality assurance. A comprehensive assessment reveals that a thorough comprehension of risk is pivotal for effective risk management and risk mitigation strategies. Furthermore, this service activity offers invaluable insights into how MSMEs can enhance their operations through risk analysis and feedback from interviews with business owners. One of the pivotal recommendations is the utilization of social media to expand market reach and enhance business reputation. Other suggestions include conducting regular risk analysis, improving branding, and building robust relationships with trusted partners or suppliers. Kegiatan pengabdian pada masyarakat ini bertujuan untuk mengevaluasi manajemen risiko pada UMKM Cahaya Sop Ikan untuk menilai keefektivitasan penanganan risiko yang dihadapi oleh usaha kuliner ini. Dengan pendekatan kualitatif, analisis ini mengidentifikasi dan menilai berbagai risiko yang dihadapi, seperti risiko persediaan bahan masakan, persaingan, harga, reputasi, kesehatan dan kualitas makanan, serta risiko keuangan. Hasil kegiatan abdimas ini menunjukkan bahwa meskipun UMKM menghadapi tantangan signifikan, pemilik usaha mampu mengatasi risiko-risiko tersebut dengan strategi yang efektif, termasuk pemberian harga dan kualitas yang kompetitif. Evaluasi mendalam menunjukkan bahwa pemahaman terhadap risiko adalah kunci untuk pengelolaan yang baik dan mitigasi risiko yang efektif. Selain itu kegiatan pengabdian ini juga memberikan wawasan berharga tentang bagaimana UMKM dapat meningkatkan operasionalnya melalui analisis risiko dan masukan dari wawancara dengan pelaku usaha. Salah satu rekomendasi utama adalah pemanfaatan media sosial untuk memperluas jangkauan pasar dan meningkatkan reputasi usaha. Saran lain termasuk melakukan analisis risiko secara rutin, meningkatkan branding, dan membangun hubungan yang kuat dengan mitra atau supplier terpercaya.
THE RELATIONSHIP OF GRADING AND HISTOPATHOLOGY WITH RESULTS OF HER-2 PATIENTS' IMMUNOHISTOCHEMICAL EXAMINATION BREAST CANCER AT DR PIRNGADI MEDAN REGIONAL GENERAL HOSPITAL IN 2018-2019 Mustika, Suryani Eka; Pangestuti, Dewi
Medicina Biomedica Journal Vol 1, No 1 (2022)
Publisher : Medicina Biomedica Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/mbj.v1i1.8086

Abstract

Basic Health Research Data 2019 explains that breast cancer prevalence that occurs in Indonesia is the second malignancy phenomenon that often afflicts women with a percentage of 0.5%, and ranked first cervical cancer as much as 0.8%. To choose and predict the prognosis, immunohistochemical examination becomes part of the mandatory examination effort. The general purpose of this study is to test the relationship of grading histopathology and histopathology types with the results of the HER-2 immunohistochemical examination of breast cancer patients at Dr. Pirngadi Medan Hospital in 2018-2019. This type of research is observational analytics conducted using the Cross- Sectional method. Secondary research data in the form of breast cancer patients in the Anatomical Pathology section of Dr. Pirngadi Medan Hospital year 2018-2019. How to take a sample by total sampling method. The statistical test used in the study is the Chi-square test. The study found 66 cases. Breast cancer cases are most common in the age range between 40 to 49 years (43.9%). The most common stages are in stage III (53.0%). This type of histopathology is found in invasive ductal carcinoma (84.8%). The most histopathological grading was grade II (63.6%). HER-2 test results found that the majority of patients had HER-2 +3 (positive 3) (59.1%). As for the Chi-Square test, if p ≤ 0.05 found a significant association and if p ≥ 0.05 did not have a significant association. There is no significant association between the type of histopathology and the results of HER-2 immunohistochemical examination (p = 0.208) and there is no significant association between grading histopathology results of HER-2 immunohistochemical examination (p = 0.492).
Edukasi Gizi Seimbang untuk Meningkatkan Pengetahuan Kader Posyandu di Kabupaten Batu Bara Ayu, Mayang Sari; Pangestuti, Dewi; Armansyah, Armansyah
Wahana Jurnal Pengabdian kepada Masyarakat Vol. 3 No. 1 (2024): Edisi Juni
Publisher : Ilmu Bersama Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56211/wahana.v3i1.524

Abstract

Pemberdayaan kader melalui edukasi menurunkan masalah gizi merupakan program penting jangka panjang. Posyandu untuk remaja perlu di aktifkan di Kabupaten Batu Bara, karena keluarga membutuhkan pembinaan, seperti pembekalan dengan penyuluhan tentang gizi seimbang untuk keluarga. Remaja putri merupakan periode penting sebagai kelompok rentan pada masalah gizi. Kabupaten Batu Bara di Propinsi Sumatera Utara memiliki prevalensi anemia dan kurang energi kronis terutama pada remaja putri cukup tinggi. Kegiatan pengabdian masyarakat bertujuan meningkatkan pengetahuan kader mengenai gizi seimbang serta makanan mencegah anemia pada remaja putri. Kegiatan ini dimulai menilai pengetahuan kader tentang gizi seimbang dengan memberikan soal pre-test sebelum edukasi, kemudian dilakukan penyuluhan dan diakhiri dengan post-test. Hasilnya dari pengetahuan kader tentang gizi seimbang menunjukkan kenaikan skor rata-rata pengetahuan yang signifikan (p=0,000) sebelum dan sesudah dilakukan edukasi gizi seimbang. Pemberian edukasi gizi seimbang oleh kader yang rutin akan meningkatkan pengetahuan tentang gizi secara signifikan. Perlu dilakukan pembinaan pada remaja putri berkelanjutan untuk menurunkan kasus anemia yang bisa menyebabkan stunting dan kurang energi kronis di masyarakat.
Pemanfaatan Daun Kelor Sebagai Makanan Sehat Pelengkap Nutrisi Dalam Mencegah Stunting Di Kabupaten Batu Bara Pangestuti, Dewi; Ayu, Mayang Sari
BEST Journal (Biology Education, Sains and Technology) Vol 7, No 1 (2024): Juni 2024
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v7i1.8827

Abstract

Tanaman Kelor atau Moringa oleifera merupakan jenis tanaman perdu yang bermanfaat untuk kesehatan Tanaman kelor dapat tumbuh beradaptasi di berbagai iklim, Kelor (Moringa oleifera Lam.) merupakan tumbuhan pohon super nutrisi sebagai sumber nutrisi masyarakat secara murah dan mudah didapat oleh masyarakat.Kegiatan Pengabdian kepada Masyarakat ini bertujuan untuk membuka wawasan dan menambah pengetahuan Masyarakat tentang manfaat daun kelor (moringa oleifera) untuk meningkatkan gizi balita, Metode yang digunakan dalam kegiatan pengabdian masyarakat ini berupa penyuluhan dengan menggunakan power point. Hasil dari kegiatan ini telah memberikan penambahan pengetahuan dan wawasan kepada masyarakat khususnya Masyarakat Desa Perupuk Kec.Lima Puluh Pesisir Kab.Batubara tentang manfaat daun kelor sebagai makanan sehat pelengkap nutrisi. Kegiatan pengabdian Masyarakat ini diharapkan dapat dilakukan secara berkelanjutan, agar penyuluhan yang sudah diberikan dapat dipraktekkan secara nyata, sehingga memberikan manfaat bagi Masyarakat Desa Perupuk Kec.Lima Puluh Pesisir Kabupaten Batubara
UJI EFEKTIVITAS KOMBINASI EKSTRAK JAHE MERAH (Zingiber Officinale Var Rubrum Rhizoma) DAN EKSTRAK KENCUR (Kaempferia Galanga L.) TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus SECARA IN VITRO Pohan, Amelya; Bestari, Ramadhan; Pangestuti, Dewi; Diba, Farah
Jurnal Kedokteran Ibnu Nafis Vol. 12 No. 1 (2023): Juni 2023
Publisher : Fakultas Kedokteran Universitas Islam Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/jkin.v12i1.507

Abstract

Staphylococcus aureus merupakan bakteri gram positif yang menyebabkan berbagai macam penyakit klinis di dunia. Staphylococcus aureus dapat menyebabkan Infeksi seperti infeksi kulit, infeksi luka, infeksi nosocomial dan sindrom syok toksik. Jahe merah dan rimpang kencur merupakan tanaman yang memiliki aktivitas sebagai antimikroba. Kencur (Kaempferia galanga L.) memiliki seyawa aktif yang terkandung didalamnya antara lain saponin, flavonoid, polifenol dan minyak atsiri. Penelitian ini bertujuan untuk mengetahui efektivitas kombinasi ekstrak jahe merah (Zingiber officinale var rubrum rhizoma) dan ekstrak kencur (Kaempferia galanga L.) terhadap pertumbuhan bakteri Staphylococcus aureus secara in vitro. Desain Penelitian ini Menggunakan desain Postest Only Control Group Desain, yang dimulai pada bulan Mei 2022 hingga Februari 2023. Adapun populasi dan sampel dari penelitian ini adalah bakteri Staphylococcus aureus yang hasilnya akan dianalisis dengan menggunakan uji ANOVA. Ekstrak kombinasi jahe merah (Zingiber officinale var rubrum) dan ekstrak Kencur (Kaempferia galanga L.) memiliki efek antibiotik terhadap pertumbuhan bakteri Staphylococcus aureus pada Ekstrak Kombinasi Jahe Merah 100% Kencur 0%, Kencur 100% Jahe merah 0%, Jahe Merah 75% Kencur 25%, Jahe merah 50% Kencur 50% dan Jahe merah 25% dan Kencur 75%.
IDENTIFYING RISK FACTORS FOR STUNTING AMONG UNDER-FIVE INDONESIAN CHILDREN Ayu, Mayang Sari; Rahmadhani, Mayasari; Pangestuti, Dewi; Ibarra, Florante
Jurnal Ilmiah Ilmu Terapan Universitas Jambi Vol. 8 No. 2 (2024): Volume 8, Nomor 2, December 2024
Publisher : LPPM Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jiituj.v8i2.34450

Abstract

The prevalence of child stunting in Indonesia in 2023 at the national level from 24.5% to 21.6%. Despite declining, the figure is still relatively high, as 28 out of 100 babies suffer from stunting. The study aims to predict stunting risk factors in children under the age of 5. They use bivariate and multivariate logistic regression to identify significant factors associated with stunting risk. Stunting prevalence in Batu Bara District of North Sumatra Province was 18.35% out of 28.716 children under 5 years of age (967 children very short and 3,944 young children). The study was conducted on 100 households with brief and concise children living in rural areas. The results of the study showed maternal education (OR 5.27; 95% CI 1.04-5.62); low maternal nutritional status during pregnancy (OR 2.57, 95% CI 1.22-5.89); formula milk delivery less than 6 months (OR 3.47; 95% CI 1.40-8.28); low birth weight of less than 2500 grams (OR 4.94; 95% CI 1.30-18.80); lack of access to drinkable water (or 3.14; 95% CI 1.29-7.65); low family wealth index (OR 0.13; 95% CI 0.05-0.32). Environmental and household factors have a significant relationship with stunting risk control. Multilateral efforts from the level of family empowerment, increasing the role of health services, and improving nutritional status are access to public health status.
Hubungan Aktivitas Fisik Terhadap Kadar Hemoglobin Pada Pekerja Bangunan Di Kota Medan Damanik, Rosa Zorayatamin; Pangestuti, Dewi; Ozar, Lucia Aktalina; Hanifa, Elza
BEST Journal (Biology Education, Sains and Technology) Vol 7, No 2 (2024): September 2024
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v7i2.10247

Abstract

Pekerja bangunan di Kota Medan memiliki jenis pekerjaannya dengan intensitas pekerjaan sedang sampai berat. Salah satu pekerjaan dengan aktifitas fisik intensitas berat seperti pekerja bangunan. Pada penelitian menganalisis mengenai aktivitas fisik pada buruh dikarenakan pekerjaan buruh yang berat dari mengangkat alat-alat berat hingga waktu kerja yang lama. Penelitian ini bertujuan untuk mengetahui hubungan aktivitas fisik terhadap kadar hemoglobin pada pekerja bangunan di Kota Medan. Jenis penelitian ini kuantitatif menggunakan observasional analitik dengan pendekatan Cross-sectional. Jumlah sampel yang digunakan adalah 30 orang pekerja bangunan di Kota Medan sampel menggunakan total sampling. Instrumen yang digunakan adalah kuisioner IPAQ untuk mengukur aktivitas fisik dan pemeriksaan Kadar Hemoglobin. Analisis data mengunakan Spearman rank. Dari 30 responden sebagian besar responden melakukan aktifitas berat sebanyak 24 orang (80%) dan 8 responden mengalami anemia (26,7%). Analisis bivariat aktivitas fisik dan kadar hemoglobin didapatkan hasil p-value 0,000 (p 0,05)
Co-Authors AA Sudharmawan, AA Akbar, Surya Aktalina, Lucia Anayya, Miska Armansyah Armansyah Aurel, Princes Ayu, Mayang Sari Brando Lubis, Adi Raja Damanik, Rosa Zorayatamin Dania, Ira Aini Fadlil, Muhammad Raihan Hanifa, Elza Harris, Bilkes Heni Nastiti Ibarra, Florante Ira Cinta Lestari Lubis, Adi Raja Brando Lubis, Tiffani Tantina Mayasari Rahmadhani Muhammad Rafli Munasiron, Munasiron Nafilaty, Najwa Laila Nanda Novziransyah Nasution, Halimah Thania Nasution, Iizzatul Aulia Halim Ozar, Lucia Aktalina Pane, Abdul Harris Pohan, Amelya Prasetyaswati, Betty Pratiwi, Munyati Putri, Dina Rachma Rachmania, Nova Rahman, Tuti Khairani Ramadhan Bestari Ritonga, Tiara Arlini Rizkillah, Saadur RR. Ella Evrita Hestiandari Saputra, Donalry Agus Sari Ayu, Mayang Sari, Siti Kemala Senny, Nila Sri Haningsih, Sri Sumilir, Sumilir Suryani Eka Mustika Syarifah Syarifah, Syarifah Varga, Fatimah