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Jurnal Penelitian Farmasi Indonesia

jpfi
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Published by Sekolah Tinggi Ilmu Farmasi Indonesia Riau

ISSN : 2302187X EISSN : 26563614 DOI : -

Core Subject : Health,

Medicine & Pharmacology

Jurnal Penelitian Farmasi Indonesia adalah publikasi ilmiah berkala yang terbit dua kali dalam satu tahun (September dan Maret) dan menggunakan sistem peer-riview dalam seleksi makalah. Jurnal Penelitian Farmasi Indonesia menerima naskah publikasi tentang hasil penelitian, survei dan telaah pustaka yang erat kaitanya dengan bidang kefarmasian dan kesehatan.

Arjuna Subject : -

Articles 7 Documents

Search results for , issue "Vol. 8 No. 2 (2019)" : 7 Documents clear

Isolasi Metabolit Sekunder dan Uji Aktivitas Antibakteri dan Antioksidan Ekstrak Metanol Kulit Batang Meranti Buaya (Shorea uliginosa Foxw) fella eka putri; enda mora
Jurnal Penelitian Farmasi Indonesia Vol. 8 No. 2 (2019)
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Telah dilakukan penelitian isolasi metabolit sekunder, uji aktivitas antibakteri dan antioksidan dari ekstrak metanol kulit batang meranti buaya (Shorea uliginosa Foxw). Ekstraksi dilakukan dengan metode maserasi menggunakan pelarut methanol. Isolasi metabolit sekunder dari ekstrak metanol dilakukan dengan menggunakan kromatografi kolom dengan metoda bergradien (Step Gradient Polarity). Hasil isolasi yang diperoleh berupa senyawa murni yang diberi label RS5 sebanyak 6 mg dengan titik leleh 240-242 ℃. Berdasarkan analisis spektroskopi UV, spektroskopi IR, dan pemeriksaan fitokimia dengan menggunakan pereaksi Liebermann-Bourchard menghasilkan warna merah bata dan disimpulkan senyawa RS5 adalah golongan Terpenoid. Hasil penelitian uji aktivitas antibakteri menunjukan bahwa ekstrak metanol kulit batang meranti buaya (Shorea uliginosa Foxw) memiliki daerah diameter hambat terhadap bakteri Staphylococcus aureus dan Escherichia coli pada kategori sedang hingga lemah, dan terhadap bakteri Bacillus cereus dan Salmonella typhi pada kategori kuat hingga lemah. Sedangkan hasil uji aktivitas antioksidan ekstrak metanol memiliki aktivitas antioksidan yang kuat dengan nilai IC50 40.1513 µg/ml dan senyawa RS5 memiliki aktivitas antioksidan sedang dengan nilai IC50 107.1968 µg/ml.

Identifikasi dan Uji Resistensi Bakteri pada Pasien Ulkus Diabetikum di Bangsal Interne RSUP Dr. M. Djamil Padang Ringga Novelni
Jurnal Penelitian Farmasi Indonesia Vol. 8 No. 2 (2019)
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Diabetic ulcers is one of diabetic mellitus’s chronic complication such as open wound on the skin and can be accompanied by necrotic tissues. High blood glucose levels become a strategic area to the development of bacteria. This study aims to determine the bacterial agent that cause of diabetic ulcer and its resistance to antibiotics. The design of this study was true experiment with diabetic ulcers patients as the subject in the ward interne at RSUP Dr. M. Djamil Padang on period February - April 2019. In this study 10 samples of diabetic ulcer patients were obtained, then bacterial identification and antibiotic resistance test was done against 5 types of antibiotics ciprofloxacin, cefotaxime, meropenem, gentamicin and vankomicin. Consecutively most of bacteria found were Klebsiella pneumonia (40%), Staphylococcus epidermidis (60%). Proteus vulgaris (10%), Proteus mirabilis (10%), Pseudomonas aeruginosa (10%) and Staphylococcus aureus (10%). Ciprofloxacin and Cefotaxime had the highest level of bacterial resistance (40%), while Vancomicin is effective to used in Staphylococcus aureus and Staphylococcus epidermidis.

Pengetahuan Masyarakat tentang Suplemen Minuman Berenergi terhadap Risiko Penyakit Ginjal Kronik di Kelurahan Simpang Baru Kecamatan Tampan Pekanbaru Yolanda Fandra; septi muharni; ratna sari dewi
Jurnal Penelitian Farmasi Indonesia Vol. 8 No. 2 (2019)
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Energy drink supplement is a health product that contains one or more substances that are nutritional (vitamins, minerals and amino acids) or drugs. This study aims to look at public knowledge about the use of energy drink supplements for the risk of chronic kidney disease in Simpang Baru district, Tampan District, Pekanbaru city. This research is an observational / survey research which is descriptive in nature. Sampling was done by purposive sampling, samples obtained in this study were 100 respondents who used energy drink supplements at least once a week. The results showed that community knowledge in the Simpang Baru sub-district was included in the sufficient category (64.83%) with the division of categories of knowledge about the definition of a supplement with enough energy drinks (62%), the content of the supplement with enough energy drinks (65.66%), the purpose / reason consume adequate energy drink supplements (75%), effects / risks after taking adequate energy drink supplements (69.6%) and when consuming energy drink supplement people in the Simpang Baru sub-district community have less knowledge level (52.33%). From these results it can be concluded that public knowledge about the use of energy drink supplements in Simpang Baru village, Tampan sub-district, Pekanbaru city is included in the sufficient category (64.83%).

Gambaran Perencanaan dan Pengadaan Obat di Puskesmas Rawat Jalan Kabupaten Rokan Hulu Tahun 2018 septia roza; erniza pratiwi
Jurnal Penelitian Farmasi Indonesia Vol. 8 No. 2 (2019)
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

A study was conducted on the description of drug planning and procurement at outpatient health centers in Rokan Hulu Regency in 2018. The purpose of this study was to look at the description of drug planning and procurement at outpatient health centers in Rokan Hulu Regency in 2018 referring to Permenkes number 74 years 2016 and see the suitability of the implementation of planning and procurement in outpatient health centers in Rokan Hulu Regency. This type of research is quantitative descriptive observational with a retrospective data collection from January to December 2018. The sample used was 13 outpatient health centers and 80 drug samples in the LPLPO. The results of his research are based on the Permenkes assessment element number 74 of 2016, the overall outpatient puskesmas drug planning system meets the requirements with a percentage of 97.43% with a very good category and the drug procurement system has reached 100%. Based on the results of conformity assessment, the suitability of drug planning reaches a percentage of 90.3% and suitability of drug procurement reaches a percentage of 79.90%.

Farmakokinetika dan Bioavailability Senyawa Golongan Santon Revew Komprehensif Meri Susanti
Jurnal Penelitian Farmasi Indonesia Vol. 8 No. 2 (2019)
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

The use of herbs for treating various ailment dates back several centuries. Evidence-based verification of the efficacy of Herbal medicines is still frequently lacking. Of particular interest is the question of bioavailability to assess to what degree and how fast compounds are absorbed after administration of herbal. Of further interest is the elucidation of metabolic pathways, and the assessment of elimination routes and their kinetics. These data become an important issue to link data from pharmacological assays and clinical effects. A better understanding of the pharmacokinetics and bioavailability of phytopharmaceuticals can also help in designing rational dosage regimens. To provide provide a detailed picture on ADME parameters (absorption, distribution, metabolism, and excretion) of some xanthone active compound, this article reviews the pharmacokinetic profile of 7 xanthones bioactive compound from the year 2009 onward.

Persepsi Masyarakat Mengenai Obat Tradisional di Kelurahan Simpang Baru Kecamatan Tampan Kota Pekanbaru RATNA SARI DEWI
Jurnal Penelitian Farmasi Indonesia Vol. 8 No. 2 (2019)
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Traditional medicine is medicine that is used empirically for traditional medical derived from plants, animals, minerals, preparations (galenic), or a mixture of these materials that can be made into various dosage forms including capsules, tablets, pills and others, without using medicinal chemicals. This study aims to determine public perceptions about traditional medicine in the Simpang Baru Village, Tampan District, Pekanbaru City. This research is an observational / survey research which is descriptive in nature. Sampling was done by purposive sampling, the sample obtained in this study were 105 respondents who had used traditional medicine the last three months. The results showed that there was still a good public perception of traditional medicine in Simpang Baru Village. From these results it can be concluded that the perceptions that arise in the community regarding traditional medicine are traditional medicines made in Indonesia, the content is safer (halal) (87.8%) and for the perception of the reasons people use traditional medicines because traditional medicines are hereditary (82.7%).

PENGARUH PEMBERIAN INFUSA DAUN KERSEN (Muntingia calabura L.) TERHADAP KADAR GLUKOSA DARAH MENCIT PUTIH (Mus musculus) YANG DIBERI BEBAN GLUKOSA mira febrina
Jurnal Penelitian Farmasi Indonesia Vol. 8 No. 2 (2019)
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

A study on the effect of cherry leaf infusion (Muntingia calabura L.) on glucose levels of male white mice (Mus musculus) given glucose load. This study aims to see the effect of cherry leaf infusion (Muntingia calabura L.) to blood glucose levels of male white mice (Mus musculus) given glucose load as much as 0.65ml / 20gBB. This research used Oral Glucose Tolerance Test (TTGO) method. Animal experiments were divided into 6 groups. The negative control group was given only aquadest, the positive group was given metformin with the dosage of 1.3mg / 20gBB, the comparison group was given 0.65ml / 20gBB glucose solution, the treatment group was given cesen leaves infusion (Muntingia calabura L.) with concentration 5, 10 and 20 %. After each test animal was given 30 minutes treatment then given glucose 0.65ml / 20gBB orally. Then measured blood glucose levels of mice at minute 30-180. Based on the results of testing the infusion of kersen leaf (Muntingia calabura L.) showed that the concentrations of 5, 10 and 20% had decreased levels of white mice blood glucose (Mus musculus) with normal control. However, the results of the two-way ANOVA assay continued with the Post Hoc Tukey test showed that the concentration of 20% differed significantly with the concentrations of 5 and 10%. And the results obtained also indicate that the duration of administration may affect the decrease in blood glucose levels of mice (p <0.05).

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