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Contact Name
Raymond Pranata
Contact Email
raymond_pranata@hotmail.com
Phone
+6282112918892
Journal Mail Official
ijc@inaheart.org
Editorial Address
Editorial Office: Heart House, Jalan Katalia Raya No. 5, Kota Bambu Utara West Jakarta, 11430 - Indonesia Telephone: +62 21 5681149, Fax: +62 21 5684220 Email: ijc@inaheart.org
Location
Kota adm. jakarta barat,
Dki jakarta
INDONESIA
Indonesian Journal of Cardiology
ISSN : 28303105     EISSN : 29647304     DOI : -
Core Subject : Health,
Indonesian Journal of Cardiology (IJC) is a peer-reviewed and open-access journal established by Indonesian Heart Association (IHA)/Perhimpunan Dokter Spesialis Kardiovaskular Indonesia (PERKI) [www.inaheart.org] on the year 1979. This journal is published to meet the needs of physicians and other health professionals for scientific articles in the cardiovascular field. All articles (research, case report, review article, and others) should be original and has never been published in any magazine/journal. Prior to publication, every manuscript will be subjected to double-blind review by peer-reviewers. We consider articles on all aspects of the cardiovascular system including clinical, translational, epidemiological, and basic studies. Subjects suitable for publication include but are not limited to the following fields: Acute Cardiovascular Care Arrhythmia / Cardiac Electrophysiology Cardiovascular Imaging Cardiovascular Pharmacotherapy Cardiovascular Public Health Policy Cardiovascular Rehabilitation Cardiovascular Research General Cardiology Heart Failure Hypertension Interventional Cardiology Pediatric Cardiology Preventive Cardiology Vascular Medicine
Articles 14 Documents
Search results for , issue "Vol. 28, No. 2 Maret 2007" : 14 Documents clear
Pengembangan Riset Kardiovaskular: Quo Vadis Indonesia? Sunu Budhi Raharjo
Jurnal Kardiologi Indonesia Vol. 28, No. 2 Maret 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i2.249

Abstract

Saat ini, derajat kesehatan masyarakat dunia meningkat beberapa kali lipat dibanding setengah abad yang lalu. Tentunya banyak faktor yang mempengaruhi, namun menurut WHO dan World Development Report ada dua kontributor terpenting yang tingkat peranannya setara (50% - 50%). Faktor pertama adalah meningkatnya tingkat pendidikan dan tingkat ekonomi masyarakat, sedangkan kontributor kedua adalah penemuan baru, pengetahuan baru serta pengembangan alat-alat baru (diagnostik, obat-obatan dan vaksin).  Sementara itu, di Amerika Serikat sendiri, dikatakan bahwa mening-katnya usia harapan hidup sampai 25 tahun dalam satu abad terakhir ini, serta membaiknya kualitas hidup masyarakatnya sangat ditentukan oleh penemuan dan pengetahuan baru dari riset biomedis. Dan, semua mafhum bahwa pengetahuan dan penemuan baru tidak mungkin terwujud tanpa adanya investasi yang  besar dan kontinyu dalam bidang riset.
Epidemiologi untuk Klinisi Eva Suarthana
Jurnal Kardiologi Indonesia Vol. 28, No. 2 Maret 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i2.250

Abstract

Pasien adalah sentrum dalam praktik klinis. Ada lima tantangan yang diberikan oleh pasien kepada dokternya, yaitu (1) berdasarkan profil dan keadaan klinisnya, apa penyakit yang sedang dialami oleh pasien? (2) mengapa penyakit ini terjadi pada pasien ini, pada saat ini? (3) bagaimana kelanjutan penyakit ini pada pasien ini? (4) apa saja pilihan terapi untuk penyakit pada pasien ini yang mungkin dapat mempengaruhi perjalanan penyakit ini. Selanjutnya, setelah diagnosis serta evaluasi kemungkinan perjalanan penyakit ditegakkan dan terpikir beberapa alternatif terapi yang ada (termasuk pilihan untuk tidak memberikan terapi sama sekali), maka tantangan terakhir adalah (5) penentuan pilihan terapi dan pelaksanaannya.
Minuman Yang Bermanfaat Untuk Kardiovaskular Anna Ulfah Rahajoe
Jurnal Kardiologi Indonesia Vol. 28, No. 2 Maret 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i2.251

Abstract

Sejak tahun 1921 penyakit jantung merupakan penyebab kematian utama di Amerika Serikat (USA), sedangkan stroke merupakan penyebab kematian nomor tiga mulai tahun 1938; kedua penyakit ini menduduki proporsi 40% dari seluruh penyebab kematian. Namun, pada tahun 1950 angka kematian akibat penyakit kardiovaskular turun 60%; keberhasilan yang luar biasa dari program kesehatan masyarakat USA di abad 20. Keberhasilan ini tercapai berkat pemahaman masyarakat yang lebih mendalam tentang faktor risiko penyakit kardiovaskular, intervensi prevensi yang dikembangkan untuk menurun-kan faktor risiko tersebut, dan tentunya juga berkat teknologi pengobatan yang semakin maju. Masyarakat di negara-negara maju kini banyak berpaling pada makanan dan minuman yang telah dibuktikan ber-manfaat untuk kesehatan kardiovaskular. Para ahli semakin faham bahwa disfungsi endotel dan aktivasi platelet, merupakan patogenesis utama aterotrombosis, yang mendorong terjadinya vasokonstriksi, pembentukan trombus dan inflamasi.
Pengaruh Pemberian Pentoksifilin Terhadap Perubahan Kadar Platelets Activating Factor pada Cedera Reperfusi-Iskemik Tungkai Akut Daf Juzar; Manoefris Kasim; Nani Hersunarti; RWM Kaligis
Jurnal Kardiologi Indonesia Vol. 28, No. 2 Maret 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i2.252

Abstract

Background. In Acute limb ischemia reperfusion causes further damage to the ischemic tissue through local compartment syndrome, and systemic syndrome: multiorgan dysfunction and failure. Several method and attempt had been studied and performed to prevent and attenuate reperfusion injury such as, ischemic preconditioning, antioxidant, and anti-cytokine therapy, but their clinical benefit were not satisfactory. Pentoxifylline (PTX) a nonspesifik phosphodiesterase derivate of xanthine has emerged as a promising agent that may attenuate inflammation response through several mechanism. However, studies on PTX and its function to prevent and attenuate inflammation response through attenuating Platelet-Activating Factor (PAF) in acute limb ischemic were not consistent. The aim of this study is to investigate the effect of PTX on PAF in rabbits with acute limb ischemic-reperfusion injury.Methods and results.Acute limb Ischemia were performed by direct occlusion of the left femoral artery of 10 New Zealand White male rabbit using non traumatic clamp, and followed by releasing the clamp after 3 hours of occlusion. The rabbits were randomly separated into 2 groups of five (PTX group and control group). The PTX group was given PTX 40 mg/kg bolus half an hour prior to reperfusion, followed by maintenance dose 1 mg/kg/hour until 2 hour post reperfusion, while the control group was given normal saline solution with comparable volume and rate administration. Level of PAF were measured after 2.5 hour of ischemic period and after 2 hours of reperfusion period. After 2.5 hours of ischemic period, the mean PAF levels did not show any significant difference (p=0.754), the mean PAF level of PTX group 13.09±0.41 pg/mL, while the control group 13.38±0.28 pg/mL. After 2 hours period of reperfusion, there were significant differences of mean PAF level between the two groups (p=0.009). The mean PAF level in the control group increase by 12.11±0.79 to became 25.5±0.78 pg/dL, while the mean PAF level of the PTX group decrease by 1.73±1.1 pg/mL and became 11.36±0.78 pg/mL.Conclusions. Pentoxifylline attenuate the production Platelet-Activating Factor level in rabbits with acute limb ischemic-reperfusion injury.
Efek Latihan Fisik Jangka Pendek yang Teratur dan Terukur terhadap Kadar High Sensitivity C-Reactive Protein pada Pasien Infark Miokard Akut Kurniawan Iskandarsyah
Jurnal Kardiologi Indonesia Vol. 28, No. 2 Maret 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i2.253

Abstract

Background. Inflammation process plays an important role in the mechanism of acute coronary syndrome (ACS).  High-sensitive C-reactive protein (hs-CRP) is an inflammatory marker and a strong predictor for cardiovascular events in patients with ACS. Previous studies have shown that half of the patients with ACS has high levels of hsCRP. This study aim to prove that the short-term, low-intensity exercise training will reduce the plasma levels of hs-CRP in patients with acute myocardial infarction.Methods and results.Thirty two male patients with acute myocardial infarction were randomized into 2 groups. The first group acquired programmed exercise training with low intensity for 5 days, while the control group did not get exercise training. Before and after this exercise training, all patients in both group did treadmill test with modified Bruce protocol. Plasma hs-CRP was examined before and after the treatment. The baseline characteristics of patients in both groups did not differ significantly. There was no significant different in the baseline levels of hs-CRP between treatment and control groups. Treadmill test significantly decreased the hs-CRP levels in both groups. Although exercise training also reduced hs-CRP levels, the reduction of hs-CRP were not different between treatment group and controls.Conclusions. This study showed that short-term, low-intensity exercise training has no effect on the levels of hs-CRP in patients with acute myocardial infarction.
Pengaruh Teh Hijau Terhadap Fungsi Endotel Dinilai dari Flow Mediated Dilatation pada Pasien Penyakit Jantung Koroner Faris Basalamah; Adnil Basha; Dede Kusmana
Jurnal Kardiologi Indonesia Vol. 28, No. 2 Maret 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i2.254

Abstract

Background. Endothelial dysfunction begins when atherosclerosis developed as what go through on hypertension, diabetes, hyper-homocysteinemia, and also what go through among smoker who hasn’t have CAD until end phase of atherosclerosis. Impairment of endothelial function depends on vasodilatation due to the decreasing of eNOS activity. Green tea has been proved to have positive effect in reversing endothelial dysfunction among healthy smoker. This study aim to prove that the short term green tea consumption improved flow mediated dilatation among coronary artery disease patients, thus reversed endothelial dysfunction. Methods and results.Twenty three coronary artery disease patients which had been confirmed by coronary angiography joined the study. The sample was divided into two groups, first was the group who took green tea, and the second was the group who took placebo (mineral water). Before treatment, the FMD of both two groups were measured and one hour and half after treatment. After 3-7 days of treatment, both groups were crossover. FMD among healthy group of age less than 25 years old was also measured as control group. There was no significant differences in baseline characteristic between the first and the second group (both received green tea but in different time). FMD after treatment was increased among group who took green tea (4.80±5.37 vs 8.68±6.00, p=0.026), while FMD among placebo group was decreased (5.87±3.89 vs 3.34±3.66 p=0.026). There was significant differences of FMD after treatment with green tea and after treatment with placebo (8.68±6.00 vs 3.35±3.66 p = 0.002). There was no differences of brachial artery diameter in both groups (4.60±0.36 vs 4.57±0.41, p=0.8 and 4.57±0.41 vs 4.61±0.36, p=0.601). There was no significant differences on systolic and diastolic blood pressure as well as heart rate in both groups. Conclusions. Green tea had positive effect in reversing endothelial dysfunction among coronary artery disease patient by assessing flow mediated dilatation in short time. The group who took placebo showed the paradoxical effect.
Gambaran Indeks Volum Atrium Kiri pada Disfungsi Diastolik Herawati Isnanijah; Ameliana M Soetanto; Muhammad Munawar
Jurnal Kardiologi Indonesia Vol. 28, No. 2 Maret 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i2.255

Abstract

Background. Diastolic dysfunction is frequently found in hypertension,usually accompanied with left ventricular hypertrophy. Several parameter was developed to assess the diastolic function including left atrial volume index, E/A, DT, IVRT, S/D, E/e’, and e’/a’. There is no data of left atrial volume index for normal subjects or subjects with hypertensive heart disease in Indonesian population. The aim of this study is to prove that left atrial volume index can be used as a parameter for left ventricular diastolic dysfunction in hypertensive heart disease.Methods and results.Fifty hypertensive heart disease patients with normal left ventricular systolic function, who were hospitalized in NCCHK between January-October 2006, and had follow up at the outpatient clinic were examined. We evaluated the correlation between left atrial volume index and E/A ratio, S/D, E/e’, e’/a’. The left atrial volume index in normal subjects is 17.64 ± 1.35, in subjects with grade 1 diastolic dysfunction 23.26 ± 2.55, while in subjects with grade 2 diastolic dysfunction 31.35 ± 2.87. Value among those groups differ significantly with p = 0.001.Conclusions. There is significant difference of left atrial volume index among normal subjects, subjects with grade 1 and grade 2 diastolic dysfunction.
Risiko Dislipidemia Pada Remaja Dengan Berat Badan Lahir Rendah Toni M Aprami
Jurnal Kardiologi Indonesia Vol. 28, No. 2 Maret 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i2.256

Abstract

Background. Abnormal lipid profile is an independent risk factor for coronary artery disease. Some studies have shown that small for gestationa age (SGA) was associated with abnormal lipid profile in adolescence and adulthood. Since 16 years ago, district Tanjungsari (Sumedang-West Java) became a research area for cohort growth studyof Frontier for Health Foundation,incooperation with Research Unit of Medical Faculty University of Padjadjaran - Bandung. This study aims to assess whether SGA children are more prone to have abnormal plasma lipid profile.Methods and results.This study was performed to cohort population in Kecamatan Tanjungsari Kabupaten Sumedang-West Java, who was born between 1988-1990. The criteria of SGA based on WHO criteria (term infants, gestational age of > 37 weeks with birth weight of < 2500 grams). Inclusion criteria were SGA and AGA with postnatal growth up to 36 month adequately, complete birth weight and birth length records up to 36 months as well and birth weight and birth length during 12-14 years of age, willing to accompany in this study. After lipid profile examination was performed, validity and stratification data of 871 subjects, 229 subjects were complied with including criteria. With the simple random, 105 subjects of dyslipidemia were decided as the group of cases and the same number of control group were included as matching. There was no difference in general character-istic of both group (age, gender, birth weight, and birth length) p > 0.05. No significant difference between total cholesterol and LDL cholesterol level in subject with SGA compared with non-SGA, p > 0.05. Triglyceride level was higher found significant in subject with SGA compared with non-SGA, p=0.00004, however the HDL cholesterol level has a significant more less in subject with SGA compared with non-SGA, p=0.00004. Subject with SGA have an increase risk to develop of dyslipidemia compare with subject non SGA, odd ratio of 3.26, 95% CI 1.77-6.02; p=00003.Conclusions. Subject with prenatal growth retardation have an increase risk for dyslipidemia development.
Efek Ekstrak Teh Rosella Merah (Hibiscus sabdariffa Linn)terhadap Penghambatan Aktifasi NF-KB, Ekspresi Protein TNF-a dan ICAM-1pada Biakan HUVECS yang Dipapar dengan Low Density Lipoprotein Teroksidasi Dwi Sarbini; Djanggan Sargowo; M Saifur Rohman
Jurnal Kardiologi Indonesia Vol. 28, No. 2 Maret 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i2.257

Abstract

Background. Atherosclerosis disease has been a global threat. Ox-LDL was one of major source of atherogenesis process, through the ROS formation which would then activate NF-KB and increase the expression of TNF-a and ICAM-1, leading to the occurrence of inflammation. Recent studies indicate that red Rosella tea is a tropical plant containing antioxidant (protocatechuic acid and antocyanin) and ascorbate acid. This tea is widely distributed in Indonesia. The mechanism of action of this tea on the inhibition of atherogenesis has not been largely known. This study aim to investigate the effect and mechanism of the red Rosella tea on the expression of NF-KB, TNF-aand ICAM-1.Methods and results.Cultured endothelial cell, HUVECs (Human Umbilical Vein Endothelial), is used for a model of endothelial cells. There are 5 groups: 1) HUVECs culture without Ox-LDL as negative control; 2) HUVECs culture with Ox-LDL as positive control; and 3 groups given various dosages of the red Rosella tea (0.001 mg/ml, 0.005 mg/ml and 0.01 mg/ml) and Ox-LDL. OxLDL (40 mg/ml) is added on HUVECs to stimulate responds of endothelial cells mimicking dyslipidemia condition. The Red Rosella tea were given 2 h before Ox-LDL treatment. The NF-KB activaton, the protein expressions of TNF-aand ICAM-1 are detected by immunohistochemistry.Treatment with red rosella tea on Ox-LDL-treated HUVECs resulted in prevention of NF-KB activation which in turn inhibited the increased of TNF-aand ICAM-1 protein expressions. Spearman‘s correlation analysis showed that there is negative correlations between dosages of red tea with NF-KB activation, TNF-aand ICAM-1 protein expressions (p=0.01, Correlation Coeff= -1).Conclusions. This study indicates the benefit of red Rosella tea on the prevention and medication for atherosclerosis disease.
Ablasi Takikardia Ventrikular dengan Pemetaan Elektro-Anatomikal 3 Dimensi Yasmin Tadjoedin; Yoga Yuniadi; Isman Firdaus; Ganesja M Harimurti; Muhammad Munawar
Jurnal Kardiologi Indonesia Vol. 28, No. 2 Maret 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i2.258

Abstract

Tingginya keberhasilan serta rendahnya morbiditas, telah menjadikan ablasi frekuensi radio transkateter sebagai terapi lini pertama pada beberapa jenis aritmia. Angka kesuksesan pada aritmia stabil dengan lokasi anatomis yang dapat diprediksi atau gambaran elektrogram intrakardiak yang khas seperti takikardia ventrikular idiopatik, atau atrial flutter yang bergantung pada ismus telah mencapai 90%.Namun, ablasi dari beberapa aritmia yang lebih kompleks seperti beberapa takikardi atrial, atrial fibrilasi, serta kebanyakan takikardia ventrikular masih merupakan tantangan besar. Hal ini disebabkan antara lain oleh keterbatasan teknik pemetaan kateter konvensional secara fluoroskopi dalam melokalisasi substrat aritmogenik. Ketidak-mampuan untuk menghubungkan secara akurat EKG intrakardiak dengan lokasi endokardium yang spesifik karena gerakan ujung kateter, juga membatasi reliabilitas pemetaan.

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